Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J. R. Rouleau"'
Publikováno v:
Canadian Journal of Kidney Health and Disease, Vol 2 (2015)
Purpose of review: Bidirectional inter-organ interactions are essential for normal functioning of the human body; however, they may also promote adverse conditions in remote organs. This review provides a narrative summary of the epidemiology, physio
Externí odkaz:
https://doaj.org/article/1381bf1a5a844ed9acab64a108bb15a0
Publikováno v:
Canadian Journal of Physiology and Pharmacology. 74:701-705
La pression tissulaire intramyocardique peut influencer la distribution du debit sanguin ventriculaire et la dynamique durant le cycle cardiaque. Les pressions tissulaires sous-endocardiques et sous-epicardiques de la paroi anterieure du ventricule g
Publikováno v:
Journal of Applied Physiology. 77:113-120
The effects of coronary flow on cardiac capillary permeability-surface area products and interstitial spaces were examined at rest and after hemodilution in the canine heart. Multiple-indicator-dilution experiments and left atrial injections of micro
Publikováno v:
Experimental physiology. 96(12)
Myocardial perfusion and contraction are closely coupled; however, the effect of recurrent no-flow ischaemia on perfusion-contraction matching remains to be established. In the present studies, we examined the influence of modulating nitric oxide ava
Publikováno v:
Canadian journal of physiology and pharmacology. 78(11)
The renin-angiotensin system plays a critical role in regulating vasoconstriction and vasodilatation that can influence myocardial blood flow and its transmural distribution. We tested the hypothesis that angiotensin inhibition can induce a leftward
Myocardial blood flow regulation relative to left ventricle pressure and volume in anesthetized dogs
Publikováno v:
Canadian journal of physiology and pharmacology. 77(11)
The influence of left ventricle pressure and volume changes on coronary blood flow was investigated in eight anesthetized dogs. Coronary artery pressure-flow relationships were determined at two levels of left ventricular pressure and volume. The dis
Autor:
M A, Pfeffer, F M, Sacks, L A, Moyé, C, East, S, Goldman, D T, Nash, J R, Rouleau, J L, Rouleau, B A, Sussex, P, Theroux, R J, Vanden Belt, E, Braunwald
Publikováno v:
Journal of the American College of Cardiology. 33(1)
We sought to assess the influence of baseline lipid levels on coronary event rates and the effectiveness of pravastatin therapy in the Cholesterol And Recurrent Events (CARE) study.The CARE study cohort provided a relatively unique opportunity to exa
Publikováno v:
The American journal of physiology. 267(1 Pt 2)
Instantaneous diastolic left coronary artery pressure-flow relations (PFR) shift during acute tamponade as pressure surrounding the heart increases. Coronary pressure at zero flow (Pf = 0) on the linear portion of the PFR is the weighted mean of the
Autor:
J. R. Rouleau, B. Cantin
Publikováno v:
Journal of applied physiology (Bethesda, Md. : 1985). 73(5)
To determine whether coronary sinus outflow pressure (Pcs) or intramyocardial tissue pressure (IMP) is the effective back pressure in the different layers of the left ventricular (LV) myocardium, we increased Pcs in 14 open-chest dogs under maximal c
Autor:
J, Turgeon, C, Fiset, R, Giguère, M, Gilbert, K, Moerike, J R, Rouleau, H K, Kroemer, M, Eichelbaum, O, Grech-Bélanger, P M, Bélanger
Publikováno v:
The Journal of pharmacology and experimental therapeutics. 259(2)
Mexiletine is a low clearance drug which undergoes extensive metabolism in man. In vitro studies with human liver microsomes have suggested that major oxidation pathways of mexiletine are predominantly catalyzed by the genetically determined debrisoq