Zobrazeno 1 - 10
of 99
pro vyhledávání: '"J. R. McINTOSH"'
Autor:
Jennifer M. Gardner, Andreas Hoenger, Christopher J. Ackerson, Mark Winey, Eileen T. O'Toole, Sue L. Jaspersen, Janet B. Meehl, J R McIntosh, Cynthia Page, Mary K. Morphew, Maria Pagratis, Thomas H. Giddings
Publikováno v:
Journal of Microscopy. 260:20-29
A benign, clonable tag for the localization of proteins by electron microscopy of cells would be valuable, especially if it provided labelling with high signal-to-noise ratio and good spatial resolution. Here we explore the use of metallothionein as
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c0434bace4cc1344c470b6cba98bf9f
https://doi.org/10.1111/jmi.12262
https://doi.org/10.1111/jmi.12262
Publikováno v:
Russian Journal of General Chemistry. 77:2006-2016
Segregation of chromosomes and their distribution to opposite ends of the cell is mediated by a mitotic spindle comprised of microtubules (polymeric structures). The forces produced by depolymerizing microtubules, responsible for chromosome motility,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0ea1ab2db9826d0058129e4042496500
https://doi.org/10.1134/s1070363207110308
https://doi.org/10.1134/s1070363207110308
Publikováno v:
Doklady Biochemistry and Biophysics. 412:18-21
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d7cd115e719249b7e8fe6106b953c83
https://doi.org/10.1134/s1607672907010061
https://doi.org/10.1134/s1607672907010061
Autor:
J. R. McIntosh, Fazoil I. Ataullakhanov, Ekaterina L. Grishchuk, Artem K. Efremov, Maxim I. Molodtsov
Publikováno v:
Proceedings of the National Academy of Sciences. 102:4353-4358
Chromosome movement during mitosis is powered in part by energy released through the depolymerization of kinetochore microtubules (MTs). Strong but indirect evidence suggests the existence of a specialized coupling between kinetochores and MT plus en
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::77b610f1a085d0384566c6159f9f3cf3
https://doi.org/10.1073/pnas.0501142102
https://doi.org/10.1073/pnas.0501142102
Publikováno v:
Proceedings of the National Academy of Sciences. 98:2399-2406
The positional relationships among all of the visible organelles in a densely packed region of cytoplasm from an insulin secreting, cultured mammalian cell have been analyzed in three dimensions (3-D) at ≈6 nm resolution. Part of a fast frozen/free
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d765f44d106ce3f6567b9b859a34c9d9
https://doi.org/10.1073/pnas.051631998
https://doi.org/10.1073/pnas.051631998
Autor:
D J Burke, Eileen T. O'Toole, Mark Winey, J R McIntosh, Thomas H. Giddings, David N. Mastronarde
Publikováno v:
Molecular Biology of the Cell. 8:1-11
The three-dimensional organization of mitotic microtubules in a mutant strain of Saccharomyces cerevisiae has been studied by computer-assisted serial reconstruction. At the nonpermissive temperature, cdc20 cells arrested with a spindle length of app
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83c7003b721e97e83162660c169bd42c
https://doi.org/10.1091/mbc.8.1.1
https://doi.org/10.1091/mbc.8.1.1
Publikováno v:
The Journal of Cell Biology
We describe two dynein heavy chain (DHC)-like polypeptides (DHCs 2 and 3) that are distinct from the heavy chain of conventional cytoplasmic dynein (DHC1) but are expressed in a variety of mammalian cells that lack axonemes. DHC2 is a distant member
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4fbb230a1551f67cd1ffda7badcb71e5
https://doi.org/10.1083/jcb.133.4.831
https://doi.org/10.1083/jcb.133.4.831
Publikováno v:
Journal of Structural Biology. 116:71-76
We have developed a computer software package, IMOD, as a tool for analyzing and viewing three-dimensional biological image data. IMOD is useful for studying and modeling data from tomographic, serial section, and optical section reconstructions. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d541ab93f93e382666393ceb27739756
https://doi.org/10.1006/jsbi.1996.0013
https://doi.org/10.1006/jsbi.1996.0013
Publikováno v:
Scopus-Elsevier
The Journal of Cell Biology
The Journal of Cell Biology
Chromosomes can move with the ends of depolymerizing microtubules (MTs) in vitro, even in the absence of nucleotide triphosphates (Coue, M., V. A. Lombillo, and J. R. McIntosh. 1991. J. Cell Biol. 112:1165-1175.) Here, we describe an immunological in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6c5f027fd75cc8476b696cb756fa5ae2
https://doi.org/10.1083/jcb.128.1.107
https://doi.org/10.1083/jcb.128.1.107
Publikováno v:
The Journal of Cell Biology
MAP 4 is a ubiquitous microtubule-associated protein thought to play a role in the polymerization and stability of microtubules in interphase and mitotic cells. We have analyzed the behavior of protein domains of MAP 4 in vivo using chimeras construc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aef31716021c0ca5782a694702a042c7
http://europepmc.org/articles/PMC2120526
http://europepmc.org/articles/PMC2120526