Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J. R. Mascola"'
Autor:
J E, Ledgerwood, E E, Coates, G, Yamshchikov, J G, Saunders, L, Holman, M E, Enama, A, DeZure, R M, Lynch, I, Gordon, S, Plummer, C S, Hendel, A, Pegu, M, Conan-Cibotti, S, Sitar, R T, Bailer, S, Narpala, A, McDermott, M, Louder, S, O'Dell, S, Mohan, J P, Pandey, R M, Schwartz, Z, Hu, R A, Koup, E, Capparelli, J R, Mascola, B S, Graham, Mary, Allen
Publikováno v:
Clinical and Experimental Immunology. 182:289-301
Summary VRC-HIVMAB060-00-AB (VRC01) is a broadly neutralizing HIV-1 monoclonal antibody (mAb) isolated from the B cells of an HIV-infected patient. It is directed against the HIV-1 CD4 binding site and is capable of potently neutralizing the majority
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::749d3342a30e22e4131e6c840063e718
https://doi.org/10.1111/cei.12692
https://doi.org/10.1111/cei.12692
Autor:
MANCINI, NICASIO, F. Canducci, D. De Marco, M. Sassi, K. Shvela, P. Bagnarelli, J. R. Mascola, M. Clementi, R. Burioni, CLEMENTI , NICOLA
The anti-human immunodeficiency virus type 1 (HIV-1) immune response is erroneously focused on highly variable regions of HIV-1 surface glycoproteins not fundamental to viral replication. However, crucial conserved portions (as the CD4-binding site -
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=od_____10495::acf32e14b5521f42598d4cd3ecdf5b44
Autor:
J R, Mascola
Publikováno v:
Methods in molecular medicine. 17
The serum titration neutralization assay described in Chapter 33 utilizes a constant amount of infectious virus and indirectly estimates the antibody-mediated reduction in infectious virus by measuring p24 antigen expressed by human peripheral blood
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::288fb4da90b966adf0943d175e013f5e
https://pubmed.ncbi.nlm.nih.gov/21380683
https://pubmed.ncbi.nlm.nih.gov/21380683
Autor:
M K, Louder, J R, Mascola
Publikováno v:
Methods in molecular medicine. 17
CD4 was identified in 1984 as the receptor for HIV-1 (1,2). However, it was soon apparent that a second receptor was necessary for HIV-1 infection of CD4(+) cells. This coreceptor was first identified by Berger and colleagues who showed that fusion a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::bb0ea74d4eae2659c57472d828bdcb51
https://pubmed.ncbi.nlm.nih.gov/21380654
https://pubmed.ncbi.nlm.nih.gov/21380654
Autor:
J R, Mascola
Publikováno v:
Methods in molecular medicine. 17
Antibodies elicited by passive or active immunization protect against numerous virus diseases. This in vivo protective immunity is often associated with in vitro detection of neutralizing antibodies (NAb) (e.g., polio, measles, influenza, respiratory
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6411ec0cb8b032075ae233683c0b08f9
https://pubmed.ncbi.nlm.nih.gov/21380682
https://pubmed.ncbi.nlm.nih.gov/21380682
Autor:
M K, Louder, J R, Mascola
Publikováno v:
Methods in molecular medicine. 17
HIV-1 is routinely isolated by cocultivation of patient PBMC with mitogen-stimulated HIV-uninfected donor PBMC (see Chapter 1 ). In this culture system, HIV-1 primarily replicates in CD4(+) T-lymphocytes, and such viruses are termed clinical or prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0be97dd99e909ea91f90eb04cbcfa226
https://pubmed.ncbi.nlm.nih.gov/21380653
https://pubmed.ncbi.nlm.nih.gov/21380653
Publikováno v:
AIDS (London, England). 14
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::89bb2b88890e47910266c289532f2a72
https://pubmed.ncbi.nlm.nih.gov/11086859
https://pubmed.ncbi.nlm.nih.gov/11086859
Autor:
S, Nitayaphan, C, Khamboonruang, N, Sirisophana, P, Morgan, J, Chiu, A M, Duliege, C, Chuenchitra, T, Supapongse, K, Rungruengthanakit, M, deSouza, J R, Mascola, K, Boggio, S, Ratto-Kim, L E, Markowitz, D, Birx, V, Suriyanon, J G, McNeil, A E, Brown, R A, Michael
Publikováno v:
Vaccine. 18(15)
Fifty-two human immunodeficiency virus type 1, seronegative Thai adults from the community were enrolled in a double-blind, placebo controlled, phase I/II trial of HIV SF2 gp120/MF59 vaccine to determine the safety and immunogenicity of this recombin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::c25d54d8a3c4b57ae1435de185b0fa3a
https://pubmed.ncbi.nlm.nih.gov/10618542
https://pubmed.ncbi.nlm.nih.gov/10618542
Autor:
T C, VanCott, R W, Kaminski, J R, Mascola, V S, Kalyanaraman, N M, Wassef, C R, Alving, J T, Ulrich, G H, Lowell, D L, Birx
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 160(4)
Because mucosal surfaces are a primary route of HIV-1 infection, we evaluated the mucosal immunogenicity of a candidate HIV-1 vaccine, oligomeric gp160 (o-gp160). In prior studies, parenteral immunization of rabbits with o-gp160 elicited broad neutra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::109c11a385f088efa6c8ce2f9fab5b51
https://pubmed.ncbi.nlm.nih.gov/9469464
https://pubmed.ncbi.nlm.nih.gov/9469464
Autor:
S S Frankel, J R Mascola, Donald S. Burke, John P. Moore, D L Birx, David D. Ho, Alexandra Trkola, Melissa Pope, Frank Isdell
Publikováno v:
Scopus-Elsevier
A report that genetic subtype E human immunodeficiency virus type 1 (HIV-1) strains display a preferential tropism for Langerhans cells (epidermal dendritic cells [DCs]) compared to genetic subtype B strains suggested a possible explanation for the r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d5449b813557a384f42be4d5b465009
https://europepmc.org/articles/PMC192162/
https://europepmc.org/articles/PMC192162/