Zobrazeno 1 - 8
of 8
pro vyhledávání: '"J. R. Manak"'
Autor:
M. Parida, J. Michaelson, J. R. Manak, Stacey L. Peek, Preeti Bais, B. J. Iverson, Ethan Bahl, Peter J. Bosch, Robert W. Burgess, Joshua A. Weiner
SummaryProper gene regulation is critical for both neuronal development and maintenance as the brain matures. We previously demonstrated that Akirin2, an essential nuclear protein that interacts with transcription factors and chromatin remodeling com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b835f9a0d7606600e9f7bf91b2fa4460
https://doi.org/10.1101/2021.07.05.451155
https://doi.org/10.1101/2021.07.05.451155
Autor:
Raghu Metpally, J. R. Manak, Matthew Rodesch, Heather A. Halvensleben, Harshavardhan Doddapaneni, Thomas J. Albert, Todd Richmond, X. Hong, F. Bolei, Chung Yi Nien, Josep M. Comeron
Publikováno v:
G3: Genes|Genomes|Genetics
Faithful annotation of tissue-specific transcript isoforms is important not only to understand how genes are organized and regulated but also to identify potential novel, unannotated exons of genes, which may be additional targets of mutation in dise
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::469880a69f38cf11879887f9b1a8f65c
https://doi.org/10.1534/g3.112.003194
https://doi.org/10.1534/g3.112.003194
Autor:
Ron Prywes, J R Manak
Publikováno v:
Molecular and Cellular Biology. 11:3652-3659
Casein kinase II (CKII) phosphorylates the mammalian transcription factor serum response factor (SRF) on a serine residue(s) located within a region of the protein spanning amino acids 70 to 92, thereby enhancing its DNA-binding activity in vitro. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::553855e208571df7eabeb71affb8754e
https://doi.org/10.1128/mcb.11.7.3652
https://doi.org/10.1128/mcb.11.7.3652
Autor:
Antonio Piccolboni, Radharani Duttagupta, Sujit Dike, Ian Bell, J R Manak, Aarron T. Willingham, Victor Sementchenko, Hari Tammana, E Cheung, David A. Nix, Jorg Drenkow, Jill Cheng, Philipp Kapranov, Madhavan Ganesh, Gregg Helt, Erica Dumais, Thomas R. Gingeras, Srinka Ghosh
Publikováno v:
Cold Spring Harbor symposia on quantitative biology. 71
Regions of the genome not coding for proteins or not involved in cis-acting regulatory activities are frequently viewed as lacking in functional value. However, a number of recent large-scale studies have revealed significant regulated transcription
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::aedc9db059fdd566c3913d614fc1b4db
https://pubmed.ncbi.nlm.nih.gov/17480199
https://pubmed.ncbi.nlm.nih.gov/17480199
Autor:
J R, Manak, M P, Scott
Publikováno v:
Development (Cambridge, England). Supplement.
Dramatic successes in identifying vertebrate homeobox genes closely related to their insect relatives have led to the recognition of classes within the homeodomain superfamily. To what extent are the homeodomain protein classes dedicated to specific
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b6de4bf1cf816b935a9d4faa75de4dc7
https://pubmed.ncbi.nlm.nih.gov/7579525
https://pubmed.ncbi.nlm.nih.gov/7579525
Autor:
J R, Manak, M P, Scott
Publikováno v:
Current biology : CB. 3(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a4d212d550bb84709d7601608c62db59
https://pubmed.ncbi.nlm.nih.gov/15335761
https://pubmed.ncbi.nlm.nih.gov/15335761
Publikováno v:
Genesdevelopment. 4(6)
Serum response factor (SRF) is a mammalian transcription factor that binds to the serum response element in the enhancer of the c-fos proto-oncogene and thus may mediate serum-induction of c-fos transcription. We report here that the DNA binding acti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df0caa69ecd70dfb0a9237fb8ff4423f
https://pubmed.ncbi.nlm.nih.gov/2200737
https://pubmed.ncbi.nlm.nih.gov/2200737
The homeo box gene even-skipped (eve) encodes a 376-amino-acid protein that binds with high affinity to sequences located near the 5' termini of the eve and en genes. The 5' en sites are A + T rich and contain copies of the 10-base-pair (bp) consensu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9611b453741dbafcd4781ad1950e9e71
https://europepmc.org/articles/PMC365548/
https://europepmc.org/articles/PMC365548/