Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J. R. Grandis"'
Autor:
S. Cheng, H. Feng, G. Y. Lopez, C. K. Kim, C. G. Duncan, A. Alvarez, R. Nishikawa, M. Nagane, A.-J. Su, P. E. Auron, M. L. Hedberg, L. Wang, J. R. Grandis, R. E. McLendon, D. D. Bigner, I. Nakano, K. Joshi, S. Kim, H.-K. Lin, F. B. Furnari, W. K. Cavenee, B. Hu, H. Yan, S.-Y. Cheng
BACKGROUND: Oncogenic EGFR-Akt signaling is aberrantly activated in human glioblastomas. Discoid, CUC and LCCL domain containing protein 2 (DCBLD2, also known as CLCP1 and ESDN) is a neuropilin-like membrane protein that is up-regulated in vascular i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b90fbb1477c636bbb6c87bea1edbf05
https://europepmc.org/articles/PMC4144529/
https://europepmc.org/articles/PMC4144529/
Publikováno v:
Cancer research. 61(15)
Clinical studies have demonstrated that retinoids, including retinol (Vitamin A) and its synthetic derivatives, can eradicate leukoplakia and suppress the formation of squamous cell carcinoma of the head and neck (SCCHN). Nonselective retinoids have
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(7)
The expression of human leukocyte antigen (HLA) class I molecules on the cell surface is necessary for the presentation of peptide antigens to cytotoxic CD8+ T lymphocytes of the immune system. Down-regulation of HLA class I gene expression has been
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 6(6)
Liarozole is a 1-substituted imidazole derivative that inhibits cytochrome P450 activity and increases endogenous plasma concentrations of retinoid acid (RA). We have previously demonstrated that RA down-modulates transforming growth factor (TGF)-alp
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 4(11)
Aberrant regulation of apoptosis may contribute to tumorigenesis. Relative levels of apoptosis regulatory proteins, such as Bcl-2 and Bax as well as interactions of these proteins with other gene products, may contribute to the rate of apoptosis in n
Publikováno v:
Journal of cellular biochemistry. 69(1)
Interruption of an autocrine growth pathway involving TGF-alpha and EGFR may inhibit tumor growth and improve survival in head and neck cancer patients. We previously demonstrated that biopsy specimens and established cell lines from patients with sq
Publikováno v:
Headneck. 19(3)
Several epidemiologic investigations have established a link between Helicobacter pylori infection and gastric malignancies. Because the stomach is in continuity with the oral cavity and the bacterium has been isolated from dental plaque and saliva,
Autor:
J R, Grandis, D J, Tweardy
Publikováno v:
Cancer research. 53(15)
The squamous mucosa of patients who develop head and neck cancer is "condemned" or predisposed to disregulated growth as reflected by the high incidence of synchronous and metachronous primary tumors. We hypothesized that transformed and nontransform
Publikováno v:
The American journal of otology. 14(2)
A retrospective review was done, examining the charts of 41 patients admitted to The Eye and Ear Hospital of Pittsburgh with a diagnosis of sudden hearing loss (SHL). Treatment consisted of (1) systemic steroids; (2) daily intravenous histamine infus
Autor:
A. P. Kotsakis, D. E. Heron, G. J. Kubicek, R. L. Ferris, S. Kim, M. K. Gibson, U. Duvvuri, J. R. Grandis, J. T. Johnson, A. Argiris
Publikováno v:
Journal of Clinical Oncology. 28:TPS264-TPS264