Feasibility of Conducting a Palliative Care Randomized Controlled Trial in Children With Advanced Cancer: Assessment of the PediQUEST Study

Autor: Kun Chen, Christina Ullrich, J R Geyer, Joanne Wolfe, Natalie Soto, Chris Feudtner, Veronica Dussel, Liliana Orellana, Tammy I. Kang

Publikováno v: Journal of Pain and Symptom Management. 49:1059-1069

Context Pediatric palliative care randomized controlled trials (PPC-RCTs) are uncommon. Objectives To evaluate the feasibility of conducting a PPC-RCT in pediatric cancer patients. Methods This was a cohort study embedded in the Pediatric Quality of

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1251dd11be420b4f7d3d9e2a0045ad04
https://doi.org/10.1016/j.jpainsymman.2014.12.010

Pediatrics Laboratory Research

Autor: K. Karakoula, D. D. Bigner, S. Keir, D. G. Thomas, J. Darling, T. Warr, H. Al-Halabi, S. Albrecht, M. C. Guiot, A. Kelkner, S. Sahebjam, P. Kavan, C. R. Freeman, T. Muanza, N. Jabado, A. Bielen, L. Perryman, G. Box, S. Popov, S. Jeay, F. Hofmann, D. Hargrave, S. Eccles, C. Jones, A. M. Dubuc, S. Mack, Y. Nakahara, L. Garzia, P. A. Northcott, P. Kongkham, S. Baylin, N. Watkins, M. D. Taylor, B. S. Paugh, C. Qu, J. Zhang, J. R. Geyer, S. Chi, N. S. da Silva, J. Baker, A. Gajjar, D. W. Ellison, A. Broniscer, S. J. Baker, L. A. Mainwaring, M. Taylor, A. Dupuy, A. M. Kenney, S. C. Williams, D. Zagzag, L. Chiriboga, O. C. Becher, A. von Deimling, J. C. Allen, M. A. Karajannis, D. Stearns, A. O. von Buren, A. Donson, N. Foreman, C. Eberhart, P. Taylor, N. Kang, C. M. Das, V. Rajaram, D. G. Aguilera, S. Goldman, J. Fangusaro, V. Gopalakrishnan, X. Su, R. Kommagani, J. E. Wolff, M. P. Kadakia, E. R. Flores

Publikováno v: Neuro-Oncology. 12:iv84-iv86

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d11e48877e323d8e2d0769939bb8e1e5
https://doi.org/10.1093/neuonc/noq116.s12

A phase II study of thioTEPA in children with recurrent solid tumor malignancies: a Children's Cancer Group study

Autor: E. Broxson, Richard L. Heideman, Frank M. Balis, J. R. Geyer, W. A. Bleyer, David G. Poplack, J K Sato, Mark Krailo

Publikováno v: Investigational New Drugs. 13:337-342

A Phase II study of thioTEPA was performed by the Children's Cancer Group. ThioTEPA was administered intravenously every three weeks, at a dose of 65 mg/m2. Pediatric patients with recurrent sarcomas were targeted, but patients with other tumor diagn

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a08c32be8c21d272635d04c4e94902d2
https://doi.org/10.1007/bf00873141

O6-Methylguanine-DNA methyltransferase in pediatric primary brain tumors: relation to patient and tumor characteristics

Autor: M S, Bobola, M S, Berger, R G, Ellenbogen, T S, Roberts, J R, Geyer, J R, Silber

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 7(3)

The DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) confers resistance to methylating and chloroethylating agents in pediatric medulloblastoma- and glioma-derived cell lines and xenografts. Here, we assayed MGMT activity in 110 pedia

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::62891abf0183afa586e46b76bb3e7afc
https://pubmed.ncbi.nlm.nih.gov/11297257

Salvage therapy after postoperative chemotherapy for primary brain tumors in infants and very young children

Autor: P G, Fisher, M N, Needle, A, Cnaan, H, Zhao, J R, Geyer, P T, Molloy, J W, Goldwein, A B, Herman-Liu, P C, Phillips

Publikováno v: Cancer. 83(3)

A trend toward the use of prolonged postoperative chemotherapy, with radiotherapy deferred until relapse, has emerged for very young children with malignant brain tumors. This study was undertaken to determine the failure patterns among infants who r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::87b9879fc8d460b8560888f103c575d9
https://pubmed.ncbi.nlm.nih.gov/9690551