Zobrazeno 1 - 10
of 47
pro vyhledávání: '"J. R. Depaulo"'
Autor:
Michael G. McCusker, Barbara W. Schweizer, Oscar J. Bienvenu, Francis M. Mondimore, James B. Potash, Fernando S. Goes, J. R. DePaulo, Dean F. MacKinnon
Publikováno v:
Psychological Medicine. 42:1449-1459
BackgroundCo-morbidity of mood and anxiety disorders is common and often associated with greater illness severity. This study investigates clinical correlates and familiality of four anxiety disorders in a large sample of bipolar disorder (BP) and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9b4590c2574778c259e5c0f4a291d1d4
https://doi.org/10.1017/s0033291711002637
https://doi.org/10.1017/s0033291711002637
Autor:
K Neimanas, Daniel B. Mirel, James A. Knowles, Jianxin Shi, A Zvinyatskovskiy, Dubravka Jancic, Peter Holmans, William Lawson, J. K. Johnson, James B. Potash, Ranjana Verma, Nancy Hale, Pablo V. Gejman, Douglas F. Levinson, William Coryell, M Gladis, Myrna M. Weissman, N Ertman, J. R. DePaulo, William A. Scheftner, M Goodell, Oleg V. Evgrafov, S Chaudhury, Alan R. Sanders, N Ney, Philip Adams
Publikováno v:
Molecular psychiatry
A genome-wide association study was carried out in 1020 case subjects with recurrent early-onset major depressive disorder (MDD) (onset before age 31) and 1636 control subjects screened to exclude lifetime MDD. Subjects were genotyped with the Affyme
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2ad8815fb79b45cf611d49e78e570bc5
https://doi.org/10.1038/mp.2009.124
https://doi.org/10.1038/mp.2009.124
Autor:
Peter P. Zandi, Pamela B. Mahon, Dean F. MacKinnon, Francis M. Mondimore, James B. Potash, Myrna M. Weissman, Jennifer L. Payne, Jianxin Shi, Peter Holmans, James A. Knowles, Barbara W. Schweizer, Fernando S. Goes, Douglas F. Levinson, William A. Scheftner, Dubravka Jancic, J. R. DePaulo, William Coryell
Publikováno v:
American Journal of Psychiatry. 166:1229-1237
Objective: Family studies have suggested that postpartum mood symptoms might have a partly genetic etiology. The authors used a genome-wide linkage analysis to search for chromosomal regions that harbor genetic variants conferring susceptibility for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ca3d0cf1787cc8c7c4dd1d332ac7fe3
https://doi.org/10.1176/appi.ajp.2009.09030417
https://doi.org/10.1176/appi.ajp.2009.09030417
Autor:
J. R. DePaulo, Celia M. T. Greenwood, Wei Xu, Shelley B. Bull, Thomas G. Schulze, Francis J. McMahon
Publikováno v:
Genetic Epidemiology. 30:155-169
By adapting a well-known affected-relative-pair linkage model that can incorporate covariate or sub-phenotype information [Olson, 1999: Am J Hum Genet 65:1760-1769], we have developed a recursive-partitioning (RP) algorithm (tree-based model) for ide
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::776d44e3982b7464f76fca45f33a206a
https://doi.org/10.1002/gepi.20135
https://doi.org/10.1002/gepi.20135
Autor:
J. R. DePaulo, Akira Sawa, Melvin G. McInnis, Lynn E. DeLisi, Colleen Callahan, Russell L. Margolis, Susan E. Holmes, T. Tsutsumi, Christopher A. Ross
Publikováno v:
American Journal of Medical Genetics. :15-19
The possible presence of anticipation in bipolar affective disorder and schizophrenia has led to the hypothesis that repeat expansion mutations could contribute to the genetic etiology of these diseases. Using the repeat expansion detection (RED) ass
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::894bf942ab84c638fbd7d8321332235c
https://doi.org/10.1002/ajmg.b.20058
https://doi.org/10.1002/ajmg.b.20058
Autor:
Theresa Swift-Scanlan, Tsuo Hung Lan, M. D. Fallin, Jennifer M. Coughlin, James B. Potash, J. R. DePaulo, Melvin G. McInnis
Publikováno v:
Psychiatric Genetics. 12:43-47
A strong genetic association between the NOTCH4 locus on chromosome 6 and schizophrenia was recently reported. Based on the data suggesting overlapping susceptibility for schizophrenia and bipolar disorder, we genotyped the polymorphic (CTG)n encodin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f767c9df07a704a8a751496614dc573f
https://doi.org/10.1097/00041444-200203000-00006
https://doi.org/10.1097/00041444-200203000-00006
Autor:
Christopher A. Ross, T. S. Breschel, Y Huo, Francis J. McMahon, Roxann Ashworth, B. Corneliussen, C. Grundstrom, Dean F. MacKinnon, Melvin G. McInnis, Kenneth K. Kidd, J. R. Depaulo, Jianfeng Xu, N. Pleasant, Thomas Grundström, Sylvia G. Simpson, Giorgio Sirugo, Russell L. Margolis
Publikováno v:
Human Molecular Genetics. 6:1855-1863
There are currently 13 diseases known to be caused by unstable triplet repeat mutations; however, there are some instances (as with FRAXF and FRA16) when these mutations appear to be asymptomatic. In a search for polymorphic CTG repeats as candidate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e62c48e75c7b91f7f6529d4539a73b3c
https://doi.org/10.1093/hmg/6.11.1855
https://doi.org/10.1093/hmg/6.11.1855
Autor:
Hugh Gurling, Pamela B. Mahon, Paul D. Shilling, Francis M. Mondimore, Virginia L. Willour, Shaun Purcell, Fayaz Seifuddin, Mehdi Pirooznia, Markus M. Nöthen, Jinyan Huang, Dean F. MacKinnon, Roy H. Perlis, James B. Potash, Jo Steele, Francis J. McMahon, Thomas G. Schulze, Jordan W. Smoller, Marcella Rietschel, J. R. DePaulo, Peter P. Zandi, Nicholas John Craddock, Phil Lee, Dubravka Jancic, John R. Kelsoe, Fernando S. Goes, Barbara W. Schweizer, Sven Cichon
Publikováno v:
Molecular psychiatry
The heritable component to attempted and completed suicide is partly related to psychiatric disorders and also partly independent of them. Although attempted suicide linkage regions have been identified on 2p11-12 and 6q25-26, there are likely many m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dc47555cfe0fd23de5dbedcb58eb49f7
https://pubmed.ncbi.nlm.nih.gov/21423239
https://pubmed.ncbi.nlm.nih.gov/21423239
Autor:
Francis M. Mondimore, Elliot S. Gershon, James B. Potash, Peter P. Zandi, Fernando S. Goes, Virginia L. Willour, J. R. DePaulo, Francis J. McMahon, Pamela L. Belmonte, Dean F. MacKinnon, Barbara W. Schweizer
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (2)
The Reelin gene (RELN) encodes a secretory glycoprotein critical for brain development and synaptic plasticity. Post-mortem studies have shown lower Reelin protein levels in the brains of patients with schizophrenia and bipolar disorder (BP) compared
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::848f3645ad345343e99e9246630a94a8
https://pubmed.ncbi.nlm.nih.gov/19691043
https://pubmed.ncbi.nlm.nih.gov/19691043
Autor:
T. Breschel, Dean F. MacKinnon, Christopher A. Ross, J. R. DePaulo, Tsuo Hung Lan, Melvin G. McInnis, Francis J. McMahon, Sylvia G. Simpson, Russell L. Margolis, H. Chen, Jennifer L. Chellis
Publikováno v:
Molecular Psychiatry. 4:217-219
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::537eb8f8ba2b1dffa18b080067be62ca
https://doi.org/10.1038/sj.mp.4000492
https://doi.org/10.1038/sj.mp.4000492