Zobrazeno 1 - 10
of 41
pro vyhledávání: '"J. R. Brock"'
Autor:
Judith Soloway, Manuel Pérez-Alonso, Graham J. R. Brock, Ruben Artero, Jonathan Houseley, Darren G. Monckton, Zongsheng Wang, Kevin M.C. O'Dell
Publikováno v:
Human Molecular Genetics. 14:873-883
Myotonic dystrophy type 1 is an autosomal dominant disorder associated with the expansion of a CTG repeat in the 3 0 untranslated region (UTR) of the DMPK gene. Recent data suggest that pathogenesis is predominantly mediated by a gain of function of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a12f6f53852ba918fc325db7b3c8351
https://doi.org/10.1093/hmg/ddi080
https://doi.org/10.1093/hmg/ddi080
Autor:
Pearlly S. Yan, Graham J. R. Brock, Andrew H.A. Hsiau, Hsiao Ling Chen, Tim H M Huang, Huidong Shi, Charles W. Caldwell, Susan H. Wei, Chuan-Mu Chen, Timothy H.C. Hsiau
Publikováno v:
The American Journal of Pathology. 163:37-45
Hypermethylation of multiple CpG islands is a common event in cancer. To assess the prognostic values of this epigenetic alteration, we developed Methylation Target Array (MTA), derived from the concept of tissue microarray, for simultaneous analysis
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a60d559f8aac1f310438f7ad4147cf48
https://doi.org/10.1016/s0002-9440(10)63628-0
https://doi.org/10.1016/s0002-9440(10)63628-0
Publikováno v:
Human Molecular Genetics. 8:1061-1067
An increasing number of human genetic disorders are associated with the expansion of trinucleotide repeats. The majority of these diseases are associated with CAG/CTG expansions, including Huntington's disease, myotonic dystrophy and many of the spin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2877b47934fe573b5a912d5647b4b8e5
https://doi.org/10.1093/hmg/8.6.1061
https://doi.org/10.1093/hmg/8.6.1061
Autor:
S. J. Legg, J. R. Brock
Publikováno v:
Ergonomics. 40:400-411
The purpose of this study was to evaluate the influence of British army recruit training on the physical fitness and strength of female recruits. A total of 73 females (aged 17-23 years) of a single intake of Women's Royal Army Corps (WRAC) recruits
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20897bfafdf63851fb87f3c2fc554207
https://doi.org/10.1080/001401397188233
https://doi.org/10.1080/001401397188233
Autor:
Graham J. R. Brock, Adrian Bird
Publikováno v:
Human Molecular Genetics. 6:451-456
The pattern of methylation in human genes for 18S and 28S ribosomal RNA has been investigated using methylation-sensitive restriction enzymes. We find that the transcribed region of the repeat unit is predominantly unmethylated, in agreement with pre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c14687cd065170e0472af9358fb2d7d5
https://doi.org/10.1093/hmg/6.3.451
https://doi.org/10.1093/hmg/6.3.451
Autor:
B. J. Jurcik, J. R. Brock
Publikováno v:
The Journal of Physical Chemistry. 97:323-331
Results are presented on a systematic investigation of particle formation and growth by homogeneous nucleation and condensation in axisymmetric free jets. The model is validated insofar as possible by comparison with available experimental data. Most
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82e58799c14bf196b8491d18873a3894
https://doi.org/10.1021/j100104a011
https://doi.org/10.1021/j100104a011
Publikováno v:
Aerosol Science and Technology. 12:842-855
A device and method for etching a body are provided capable of etching fine geometry patterns utilizing the high selectivity of wet etching and the anisotropic etch characteristics of dry etching. The body to be etched is placed in a reduced pressure
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a46212ea9af83701197415b54b9ada5e
https://doi.org/10.1080/02786829008959397
https://doi.org/10.1080/02786829008959397
Publikováno v:
Applied Physics Letters. 63:3341-3343
A new etching technique, reactive cluster etching, has been developed, using a cluster beam of ultrafine particles formed by supersonic nozzle expansion. The method demonstrates good anisotropy and selectivity in delineation of submicrometer patterns
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::07159014c4325c2ec1f77d1e38265cf4
https://doi.org/10.1063/1.110164
https://doi.org/10.1063/1.110164
Publikováno v:
Applied Physics Letters. 60:486-488
Laser‐assisted wet etching (LAWE) of n‐silicon using a 514.5‐nm line from a cw argon‐ion laser in the presence of hydrofluoric acid is reported. The effects of laser fluence, doping level, and acid concentration on the etch rate are investiga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a3745fe33be903ba687a56be2a469d1
https://doi.org/10.1063/1.106644
https://doi.org/10.1063/1.106644
Publikováno v:
Gene. 240(2)
We have constructed a library of densely methylated DNA sequences from human blood DNA by selecting fragments with a high affinity for a methyl-CpG binding domain (MBD) column. PCR analysis of the library confirmed the presence of known densely methy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84e86ec3c4d9771dcddf063386f8a806
https://pubmed.ncbi.nlm.nih.gov/10580146
https://pubmed.ncbi.nlm.nih.gov/10580146