Výsledky vyhledávání - "J. R. A. SHERWIN"

Global gene analysis of late secretory phase, eutopic endometrium does not provide the basis for a minimally invasive test of endometriosis

Autor: Attila Mihalyi, Peter Simsa, R. D. Catalano, Thomas D'Hooghe, J. R. A. Sherwin, Andrew M. Sharkey

Publikováno v: Human Reproduction. 23:1063-1068

BACKGROUND: Endometriosis occurs in 10% of women and is currently diagnosed by invasive laparoscopic testing. We tested the hypothesis that endometrial gene expression in late secretory phase endometrium differs between patients with and without endo

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::204ca1e6904d2bf96062f713c5f415db
https://doi.org/10.1093/humrep/den078

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The Endometrial Response to Chorionic Gonadotropin Is Blunted in a Baboon Model of Endometriosis

Autor: Andrew M. Sharkey, Julie Hastings, Asgerally T. Fazleabas, Patricia A. Mavrogianis, J. R A Sherwin, Kevin S. Jackson

Endometriosis-associated infertility has a multifactorial etiology. We tested the hypothesis that the endometrial response to the early embryonic signal, human chorionic gonadotropin (hCG), alters over time in a nonhuman primate model of endometriosi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38175ed477af37eab5e336c1a87a6073
https://europepmc.org/articles/PMC2946138/

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Mifepristone induced progesterone withdrawal reveals novel regulatory pathways in human endometrium

Autor: R. D. Catalano, D. T. Baird, Andrew M. Sharkey, Dharani K. Hapangama, J. R. A. Sherwin, David Stephen Charnock-Jones, Oskari Heikinheimo, Hilary O. D. Critchley, Stephen K. Smith

Publikováno v: Molecular human reproduction. 13(9)

In women, a single dose of the antiprogestin mifepristone (RU486) in the secretory phase rapidly renders the endometrium unreceptive and is followed by endometrial breakdown and menstruation within 72 h. This model provides a system to identify proge

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8bcf36f7192d79f9a4668e5ed66706e3
https://pubmed.ncbi.nlm.nih.gov/17584828

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Identification of novel genes regulated by chorionic gonadotropin in baboon endometrium during the window of implantation

Autor: J. R. A. Sherwin, Asgerally T. Fazleabas, Paula Cameo, P. M. Mavrogianis, Seby L. Edassery, R. D. Catalano, Andrew M. Sharkey

Publikováno v: Endocrinology. 148(2)

Chorionic gonadotropin (CG) is an early embryo-derived signal that is known to support the corpus luteum. An in vivo baboon model was used to study the direct actions of human CG (hCG) on the endometrium, during the periimplantation period. Endometri

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebbcc16914d2b855e57a65d511a9e9f4
https://pubmed.ncbi.nlm.nih.gov/17110430

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Effect of an intrauterine device on the gene expression profile of the endometrium

Autor: Antonio Pellicer, R. D. Catalano, José A. Horcajadas, M. R. Peraza, Carlos Simón, Andrea Castro, L. A. Burgos, Andrew M. Sharkey, J. R. A. Sherwin, Francisco Domínguez

Publikováno v: The Journal of clinical endocrinology and metabolism. 91(8)

The human endometrium acquires the ability to allow embryo attachment just for a specific period of time during each menstrual cycle. Understanding of the opposite functional status, referred to as refractoriness, can potentially be used to improve r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::988b2dd5c355f7f054601061c763d473
https://pubmed.ncbi.nlm.nih.gov/16735486

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Regulation of embryo–endometrial interactions at implantation

Autor: Andrew Sharkey, J. R. A. Sherwin

Publikováno v: A Textbook of In Vitro Fertilization and Assisted Reproduction: The Bourn Hall Guide to Clinical and Laboratory Practice

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::98775459dfaeab21b843552ba80a7fcf
https://doi.org/10.1201/b14680-25

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Identification of genes regulated by leukemia-inhibitory factor in the mouse uterus at the time of implantation

Autor: Austin Smith, Ian Chambers, Susan J. Kimber, Tom C. Freeman, R. J. Stephens, Andrew M. Sharkey, Stephen K. Smith, J. R. A. Sherwin

Publikováno v: Molecular endocrinology (Baltimore, Md.). 18(9)

The endometrium is prepared for implantation by the actions of estradiol (E2) and progesterone (P4). In mice the luminal epithelium (LE) only becomes fully receptive to the attaching blastocyst in response to the nidatory estrogen surge on d 4 of pre

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::165d5614fb4b6f06908f44491a48dd43
https://pubmed.ncbi.nlm.nih.gov/15178747

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Soluble gp130 is up-regulated in the implantation window and shows altered secretion in patients with primary unexplained infertility

Autor: J. R. A. Sherwin, Stephen K. Smith, Andrew M. Sharkey, A. Wilson

Publikováno v: The Journal of clinical endocrinology and metabolism. 87(8)

Members of the IL-6 family of cytokines, which includes leukemia inhibitory factor (LIF) and IL-11, play important roles in implantation. The activity of these cytokines is modified by soluble receptors such as the IL-6 receptor (sIL-6R). gp130 is a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3fc184e6845e926497e8c1188fb7f02d
https://pubmed.ncbi.nlm.nih.gov/12161539

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