Zobrazeno 1 - 10
of 193
pro vyhledávání: '"J. Punnonen"'
Akademický článek
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Publikováno v:
Immunology. 100:238-244
To investigate the role of the CD40-CD154 interaction in rheumatoid arthritis (RA), we analysed the expression of CD154 on CD3+ and CD4+ T cells in synovial fluid (SF) from patients with RA and in peripheral blood (PB) from patients and normal contro
Publikováno v:
European Journal of Endocrinology. :393-401
The present study was designed to investigate the growth regulatory effects of cytokines in UT-OC-3 ovarian cystadenocarcinoma cells in vitro. The effects of interleukin-6 (IL-6), interferons alpha (IFN-alpha) and gamma (IFN-gamma), granulocyte-macro
Publikováno v:
Immunology. 96:358-364
The balance between T helper type 1 (Th1) and Th2 cytokines is thought to be important in the initiation and outcome of autoimmune diseases. The goal of the present study was to compare the production of interferon-gamma (IFN-gamma) and interleukin-4
Interleukin-10 inhibits the capacity of synovial macrophages to function as antigen-presenting cells
Publikováno v:
Rheumatology. 37:1207-1214
SUMMARY Objective. We have investigated the eVects of interleukin (IL)-10, IL-4+ granulocyte/macrophage colony-stimulating factor (GM-CSF ) and tumour necrosis factor alpha (TNF-a) on the phenotype and antigen-presenting capacity of synovial fluid (S
Akademický článek
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Autor:
J M Carballido, G Aversa, K Kaltoft, B G Cocks, J Punnonen, H Yssel, K Thestrup-Pedersen, J E de Vries
Publikováno v:
The Journal of Immunology. 159:4316-4321
Allergen-specific Th2 cells accumulate at high frequencies in the skin of patients with atopic dermatitis (AD), where they contribute to the induction and maintenance of the lesions that are characteristic for the disease. Attenuation of these lesion
Publikováno v:
The Journal of Immunology. 159:2986-2993
In the present study the expression and function of signaling lymphocytic activation molecule (SLAM) in lymphocytes from patients with rheumatoid arthritis (RA) were investigated. The expression levels of SLAM were significantly up-regulated on synov
Publikováno v:
The Journal of Immunology. 155:4248-4254
The present study demonstrates that IL-4 induces germ-line IgE heavy chain (epsilon) gene transcription in human fetal splenic mononuclear cells; fetal bone marrow cells; highly purified sorted surface (s) mu+, CD10+, CD19+ immature B cells; and s mu
Autor:
J Punnonen, J E de Vries
Publikováno v:
The Journal of Immunology. 152:1094-1102
In this study it is demonstrated that the novel T cell-derived cytokine IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by human immature B cells derived from fetal bone marrow (BM). IL-13 induced proliferation and IgM, total IgG,