Zobrazeno 1 - 10
of 24
pro vyhledávání: '"J. Prekajac"'
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 111:110-114
Diethylstilbestrol (DES), diethylstilbestrol monophosphate (DES-MP) and diethylstilbestrol diphosphate (DES-DP) were tested for their estrogen receptor affinity, estrogenic potency and mammary tumor-inhibiting activity in vitro and in vivo. DES had a
Publikováno v:
Journal of Cancer Research and Clinical Oncology. 110:216-220
The antineoplastic activity of 4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-1-ethyl-6-hydroxyindole (D 15413) was determined in several estrogen-dependent mammary tumor models. The growth of DMBA-induced rat mammary carcinomas was inhibited by doses ran
Autor:
Erwin von Angerer, J. Prekajac
Publikováno v:
Journal of Medicinal Chemistry. 29:380-386
A number of 11-alkylbenzo[a]carbazoles and their 5,6-dihydro derivatives with one or two hydroxy groups in the aromatic rings were synthesized and studied for their binding affinities for the estrogen receptor. Best conditions for the receptor bindin
Publikováno v:
Chemischer Informationsdienst. 16
A number of 2-phenylindole derivatives with one hydroxy group in the meta or para position of the phenyl ring and a second one in position 5, 6, or 7 of the indole nucleus were synthesized. In addition, different alkyl groups were introduced into pos
Autor:
Erwin von Angerer, J. Prekajac
1-Alkyl-4-chloro-2-(2,6-dichloro-4-hydroxyphenyl)-6-hydroxyindoles (4, alkyl = CH3, C2H5, C3H7) were synthesized by thermolysis of the corresponding N,N'-dialkyl-1,2-diphenylethylenediamines and subsequent ether cleavage. They showed an affinity for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5ad8f53923b22716c73aeafd514b893b
Publikováno v:
Cancer Chemotherapy and Selective Drug Development ISBN: 9781461338390
Derivatives of 2-phenylindole inhibit the growth of estrogen-dependent mammary tumours (Von Angerer and Prekajac, J. Med. Chem. 26: 113, 1983). The title compound was selected for further studies because of the high affinity of its free hydroxy deriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ffcaf2a06f60b9e0a5f56bdc04a6497
https://doi.org/10.1007/978-1-4613-3837-6_86
https://doi.org/10.1007/978-1-4613-3837-6_86
Publikováno v:
Journal of medicinal chemistry. 27(11)
A number of 2-phenylindole derivatives with one hydroxy group in the meta or para position of the phenyl ring and a second one in position 5, 6, or 7 of the indole nucleus were synthesized. In addition, different alkyl groups were introduced into pos
Autor:
E. von Angerer, J. Prekajac
Publikováno v:
Chemischer Informationsdienst. 14
Publikováno v:
European journal of cancerclinical oncology. 21(4)
The antineoplastic activity of the antiestrogen 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) was determined in several estrogen-dependent mammary tumor models. The growth of the DMBA-induced rat mammary carcinoma was inhibited by do
Autor:
J. Prekajac, E. von Angerer
Publikováno v:
Chemischer Informationsdienst. 17