Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J. Popov-Celeketic"'
Autor:
M. Teunissen, B.P. Meij, L. Snel, K. Coeleveld, J. Popov-Celeketic, I.S. Ludwig, F. Broere, F.P.J.G. Lafeber, M.A. Tryfonidou, S.C. Mastbergen
Publikováno v:
Journal of Orthopaedic Translation, Vol 38, Iss , Pp 44-55 (2023)
Background: Cartilage regenerative mechanisms initiated by knee joint distraction (KJD) remain elusive. Animal experiments that are representative for the human osteoarthritic situation and investigate the effects of KJD at consecutive time points co
Externí odkaz:
https://doaj.org/article/90b3f6e7f2f243d7b4428f2cc86629ab
Autor:
Sabine Versteeg, E.M. van Helvoort, Niels Eijkelkamp, Harrie Weinans, H.M. de Visser, J. Popov-Celeketic, Simon C. Mastbergen, K. Coeleveld, F.P.J.G. Lafeber
Publikováno v:
Cartilage
Objective Ideally, disease-modifying osteoarthritis (OA) drugs (DMOAD) should combine chondroprotective, anti-inflammatory, and analgesic effects in a single molecule. A fusion protein of interleukin-4 (IL-4) and IL-10 (IL4-10 FP) possesses these com
Autor:
Niels Eijkelkamp, J. Popov-Celeketic, Ana P Lopes, J.A. van Roon, F.P.J.G. Lafeber, Cornelis E. Hack, M. B.M. de Smet, Sarita A. Y. Hartgring, C. Steen-Louws
Publikováno v:
Clinical and Experimental Immunology, 195(1), 1. Wiley-Blackwell
Clinical and Experimental Immunology
Clinical and Experimental Immunology
Summary The objective of this study was to test the capacity of a newly developed fusion protein of interleukin 4 (IL-4) and IL-10 [IL4-10 fusion protein (FP)] to shift multiple pro-inflammatory pathways towards immune regulation, and to inhibit pro-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3b1c0001998677bea40e674570332287
https://dspace.library.uu.nl/handle/1874/392183
https://dspace.library.uu.nl/handle/1874/392183
Autor:
J. Popov-Celeketic, M. Teunissen, K. Coeleveld, F.P.J.G. Lafeber, S.C. Mastbergen, Marianna A. Tryfonidou, Björn P. Meij
Publikováno v:
Annals of the Rheumatic Diseases. 79:242.1-242
Background:Knee joint distraction (KJD) is a validated joint-preserving treatment strategy for severe osteoarthritis (OA) that provides long-term clinical and structural improvement. Human trials and animal models indicate clear cartilage regeneratio
Autor:
EM Van Helvoort, F.P.J.G. Lafeber, S.C. Mastbergen, J. Popov-Celeketic, K. Coeleveld, Marianna A. Tryfonidou, C. D. Wijne, A. Doornenbal
Publikováno v:
FRIDAY, 15 JUNE 2018.
Background An ideal disease modifying osteoarthritis (OA) drug should have analgesic, chondroprotective and anti-inflammatory effects. A fusion protein of Interleukin 4 and 10 (IL4–10FP) might have these effects. Objectives This study evaluates the
Publikováno v:
Journal of Visualized Experiments, 2018(134). MYJoVE Corporation
Chronic pain is difficult to treat and new approaches to resolve persistent pain are urgently needed. Anti-inflammatory cytokines are promising candidates for treating debilitating pain conditions due to their capacity to regulate aberrant neuro-immu
Autor:
Marianna A. Tryfonidou, J. Popov-Celeketic, K. Coeleveld, F.P.J.G. Lafeber, EM Van Helvoort, S.C. Mastbergen
Publikováno v:
Poster Presentations.
Background Ideally a disease modifying osteoarthritis drug (DMOAD) combines treatment for pain, tissue damage and inflammation, all in one molecule. Intra-articular application of a DMOAD brings additional value to treatment for two reasons, (i) lowe
Autor:
K. Coeleveld, C. D. Wijne, Marianna A. Tryfonidou, E.M. van Helvoort, F.P.J.G. Lafeber, J. Popov-Celeketic, Simon C. Mastbergen, A. Doornenbal
Publikováno v:
Osteoarthritis and Cartilage. 26:S285-S286
Autor:
Harrie Weinans, H.M. de Visser, F.P.J.G. Lafeber, S.C. Mastbergen, C. Steen-Louws, J. Popov-Celeketic, K. Coeleveld, Cornelis E. Hack
Publikováno v:
Osteoarthritis and Cartilage. 26:S292
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