Zobrazeno 1 - 10
of 178
pro vyhledávání: '"J. Ponder"'
Autor:
Joana M. Xavier, Ramiro Magno, Roslin Russell, Bernardo P. de Almeida, Ana Jacinta-Fernandes, André Besouro-Duarte, Mark Dunning, Shamith Samarajiwa, Martin O’Reilly, António M. Maia, Cátia L. Rocha, Nordiana Rosli, Bruce A. J. Ponder, Ana-Teresa Maia
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract Understanding breast cancer genetic risk relies on identifying causal variants and candidate target genes in risk loci identified by genome-wide association studies (GWAS), which remains challenging. Since most loci fall in active gene regul
Externí odkaz:
https://doaj.org/article/5911727bfc684d7781c670c96a6ca054
Autor:
Maria Stella de Biase, Florian Massip, Tzu-Ting Wei, Federico M. Giorgi, Rory Stark, Amanda Stone, Amy Gladwell, Martin O’Reilly, Daniel Schütte, Ines de Santiago, Kerstin B. Meyer, Florian Markowetz, Bruce A. J. Ponder, Robert C. Rintoul, Roland F. Schwarz
Publikováno v:
Genome Medicine, Vol 16, Iss 1, Pp 1-19 (2024)
Abstract Background Lung cancer is the leading cause of cancer-related death in the world. In contrast to many other cancers, a direct connection to modifiable lifestyle risk in the form of tobacco smoke has long been established. More than 50% of al
Externí odkaz:
https://doaj.org/article/1477c061531644cca19787d9aa30b28b
Autor:
Kerstin B. Meyer, Bruce A. J. Ponder, Kelin Gonçalves de Oliveira, Mauro A. A. Castro, Thomas M. Campbell
Full data set obtained in RIME experiment.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12eb8c94f428fb928f81fb7a6bfc990e
https://doi.org/10.1158/0008-5472.22417001.v1
https://doi.org/10.1158/0008-5472.22417001.v1
Autor:
Kerstin B. Meyer, Bruce A. J. Ponder, Kelin Gonçalves de Oliveira, Mauro A. A. Castro, Thomas M. Campbell
Supplementary Material: Figure S1: Nuclear localisation and fluorescent properties of FRET constructs Figure S2: Quantification of FRET experiment Figure S3: Relative mRNA expression of ESR1 target genes Figure S4: Characterisation of MCF-7 clones ov
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1da0600a330d1478eae9268e36c6b6ca
https://doi.org/10.1158/0008-5472.22417004
https://doi.org/10.1158/0008-5472.22417004
Autor:
Kerstin B. Meyer, Bruce A. J. Ponder, Kelin Gonçalves de Oliveira, Mauro A. A. Castro, Thomas M. Campbell
Two opposing clusters of transcription factors (TF) have been associated with the differential risks of estrogen receptor positive or negative breast cancers, but the mechanisms underlying the opposing functions of the two clusters are undefined. In
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::349a6d743d95da357b5f2074fa486db8
https://doi.org/10.1158/0008-5472.c.6509708.v1
https://doi.org/10.1158/0008-5472.c.6509708.v1
Autor:
Joana M. Xavier, Ramiro Magno, Roslin Russell, Bernardo P. de Almeida, Ana Jacinta-Fernandes, André Duarte, Mark Dunning, Shamith Samarajiwa, Martin O’Reilly, Cátia L. Rocha, Nordiana Rosli, Bruce A. J. Ponder, Ana Teresa Maia
BackgroundBreast cancer (BC) genome-wide association studies (GWAS) have identified hundreds of risk-loci that require novel approaches to reveal the causal variants and target genes within them. As causal variants are most likely regulators of gene
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::3cf8d7dc0d6587efcf82f993c79739fb
https://doi.org/10.1101/2022.03.08.22271889
https://doi.org/10.1101/2022.03.08.22271889
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0168770 (2016)
We have recently identified transcription factors (TFs) that are key drivers of breast cancer risk. To better understand the pathways or sub-networks in which these TFs mediate their function we sought to identify upstream modulators of their activit
Externí odkaz:
https://doaj.org/article/94de4758fde2418883519ba4c5862f0f
Autor:
Travis Nemkov, John M. Ashton, Nabilah Khan, Anna Krug, Maria L. Amaya, Jeffrey Schowinsky, Jonathan A. Gutman, Shanshan Pei, Andrew Hammes, Kent Riemondy, Diana Abbott, Brett M. Stevens, Anagha Inguva, Courtney L. Jones, Biniam Adane, Ryan M. Sheridan, Angelo D'Alessandro, Jihye Kim, Michael R. Savona, J Ponder, Daniel A. Pollyea, Clayton A. Smith, Mohammad Minhajuddin, Haley E. Ramsey, James C. Costello, Annika Gustafson, Rui Fu, Amanda Winters, Austin E. Gillen, Haobin Ye, Jason R. Myers, Craig T. Jordan
Publikováno v:
Cancer Discov
Venetoclax-based therapy can induce responses in approximately 70% of older previously untreated patients with acute myeloid leukemia (AML). However, up-front resistance as well as relapse following initial response demonstrates the need for a deeper
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d5114d3252e1c0c41a77c7f29a896d6
https://doi.org/10.1158/2159-8290.cd-19-0710
https://doi.org/10.1158/2159-8290.cd-19-0710
Autor:
Maria Stella de Biase, Florian Massip, Tzu-Ting Wei, Federico M. Giorgi, Rory Stark, Amanda Stone, Amy Gladwell, MarJn O’Reilly, Daniel Schütte, Ines de Santiago, Kerstin B. Meyer, Florian Markowetz, Bruce A J Ponder, Robert C Rintoul, Roland F Schwarz
Lung cancer is the leading cause of cancer-related death in the world. In contrast to many other cancers, a direct connection to modifiable lifestyle risk in the form of tobacco smoke has long been established. More than 50% of all smoking-related lu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b456f9b75d9f702532915e7f14ad6df8
https://doi.org/10.1101/2021.11.24.21266740
https://doi.org/10.1101/2021.11.24.21266740
Autor:
Milena A Cardoso, Luis E A Rizzardi, Leonardo W Kume, Clarice S Groeneveld, Sheyla Trefflich, Diego A A Morais, Rodrigo J S Dalmolin, Bruce A J Ponder, Kerstin B Meyer, Mauro A A Castro
Publikováno v:
Bioinformatics (Oxford, England). 38(5)
Motivation Dendrogram is a classical diagram for visualizing binary trees. Although efficient to represent hierarchical relations, it provides limited space for displaying information on the leaf elements, especially for large trees. Results Here, we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d22dabc341e31234675204842270fae5
https://pubmed.ncbi.nlm.nih.gov/34864914
https://pubmed.ncbi.nlm.nih.gov/34864914