Zobrazeno 1 - 10
of 747
pro vyhledávání: '"J. Pollak"'
Publikováno v:
Molecular Therapy: Nucleic Acids, Vol 33, Iss , Pp 832-844 (2023)
Single-stranded phosphorothioate oligonucleotides (PS-oligos) can activate TLR9, leading to an innate immune response. This can occur with PS-oligos containing unmethylated CpG sites, the canonical motif, or PS-oligos that do not contain those motifs
Externí odkaz:
https://doaj.org/article/4f3cba99e8d34c71ad01fbcae30d0bc0
Publikováno v:
PLoS ONE, Vol 18, Iss 2, p e0278316 (2023)
With the oncoming age of big data, biologists are encountering more use cases for cloud-based computing to streamline data processing and storage. Unfortunately, cloud platforms are difficult to learn, and there are few resources for biologists to de
Externí odkaz:
https://doaj.org/article/260320f323274ddd8f6d0c5966e76627
Publikováno v:
Nucleic Acid Therapeutics. 33:95-107
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::049cdb549c72a0b364f5a1a7e226fdad
https://doi.org/10.1089/nat.2022.0067
https://doi.org/10.1089/nat.2022.0067
Publikováno v:
Nucleic Acids Research. 50:8107-8126
Non-CpG PS-ASOs can activate the innate immune system, leading to undesired outcomes. This response can vary—in part—as a function of 2′modifications and sequence. Here we investigated the molecular steps involved in the varied effects of PS-AS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::63cebe7fd7d78a595a42e25c1fe51626
https://doi.org/10.1093/nar/gkac618
https://doi.org/10.1093/nar/gkac618
Publikováno v:
BMJ Open, Vol 9, Iss 6 (2019)
ObjectivesThe objective of our review was to systematically assess available evidence on the effectiveness, safety and efficiency of a spring sensor-irrigated contact force (CF) catheter (THERMOCOOL SMARTTOUCH Catheter (ST)) for percutaneous ablation
Externí odkaz:
https://doaj.org/article/253a5c849a754509ad8f6bfdb825e4d2
Autor:
Adam J Pollak, Canzhao Liu, Aparna Gudlur, Joshua E Mayfield, Nancy D Dalton, Yusu Gu, Ju Chen, Joan Heller Brown, Patrick G Hogan, Sandra E Wiley, Kirk L Peterson, Jack E Dixon
Publikováno v:
eLife, Vol 7 (2018)
Ca2+ signaling is important for many cellular and physiological processes, including cardiac function. Although sarcoplasmic reticulum (SR) proteins involved in Ca2+ signaling have been shown to be phosphorylated, the biochemical and physiological ro
Externí odkaz:
https://doaj.org/article/ecc097f1b4894d6997ab24d9a2cc0ed7
Akademický článek
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Autor:
Jung-Hoon Lee, Jeffrey R. Long, Rebecca L. Siegelman, Alexander C. Forse, Henry Z. H. Jiang, Bhavish Dinakar, Phillip J. Milner, Eugene Kim, Jeffrey A. Reimer, Ziting Zhu, Surya T. Parker, Connor J. Pollak
Publikováno v:
Journal of the American Chemical Society. 143:15258-15270
Carbon capture at fossil fuel-fired power plants is a critical strategy to mitigate anthropogenic contributions to global warming, but widespread deployment of this technology is hindered by a lack of energy-efficient materials that can be optimized
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::767d642602980afecc12b6ea2c9ab94c
https://doi.org/10.1021/jacs.1c06434
https://doi.org/10.1021/jacs.1c06434
Autor:
Adam J. Pollak, Patrick Cauntay, Todd Machemer, Suzanne Paz, Sagar Damle, Scott P. Henry, Sebastien A. Burel
Publikováno v:
Nucleic acid therapeutics. 32(6)
Nucleic acid-based phosphorothioate containing antisense oligonucleotides (PS-ASOs) have the potential to activate cellular innate immune responses, and the level of activation can vary quite dramatically with sequence. Minimizing the degree of proin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d64d0c288e1d853feb9e2dc04639b79d
https://pubmed.ncbi.nlm.nih.gov/36355073
https://pubmed.ncbi.nlm.nih.gov/36355073
Akademický článek
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