Zobrazeno 1 - 10
of 290
pro vyhledávání: '"J. Plattner"'
Autor:
Blake J. Plattner, Shan Hong, Yonghui Li, Martin J. Talavera, Hulya Dogan, Brian S. Plattner, Sajid Alavi
Publikováno v:
Foods, Vol 13, Iss 8, p 1195 (2024)
A new form of plant-based meat, known as ‘high-moisture meat analogs’ (HMMAs), is captivating the market because of its ability to mimic fresh, animal muscle meat. Utilizing pea protein in the formulation of HMMAs provides unique labeling opportu
Externí odkaz:
https://doaj.org/article/2a152f3d4c9d4b429e770c83177b2cd5
Autor:
Christopher S. Lunde, Erin E. Stebbins, Rajiv S. Jumani, Md Mahmudul Hasan, Peter Miller, John Barlow, Yvonne R. Freund, Pamela Berry, Rianna Stefanakis, Jiri Gut, Philip J. Rosenthal, Melissa S. Love, Case W. McNamara, Eric Easom, Jacob J. Plattner, Robert T. Jacobs, Christopher D. Huston
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Cryptosporidium infection can cause severe diarrhea with limited treatment options available. Here, Lunde et al. perform a drug repositioning screen with a library of benzoxaboroles and identify AN7973 as potent inhibitor of intracellular parasite de
Externí odkaz:
https://doaj.org/article/9ffc28868e0b404a868e8f4e98e9bbf7
Autor:
Kirthana M. V. Sindhe, Wesley Wu, Jenny Legac, Yong-Kang Zhang, Eric E. Easom, Roland A. Cooper, Jacob J. Plattner, Yvonne R. Freund, Joseph L. DeRisi, Philip J. Rosenthal
Publikováno v:
mBio, Vol 11, Iss 1 (2020)
ABSTRACT New antimalarial drugs are needed. The benzoxaborole AN13762 showed excellent activity against cultured Plasmodium falciparum, against fresh Ugandan P. falciparum isolates, and in murine malaria models. To gain mechanistic insights, we selec
Externí odkaz:
https://doaj.org/article/f9067457c1d346e893d1e74840fb86f1
Autor:
Alexandra Ehrens, Christopher S Lunde, Robert T Jacobs, Dominique Struever, Marianne Koschel, Stefan J Frohberger, Franziska Lenz, Martina Fendler, Joseph D Turner, Stephen A Ward, Mark J Taylor, Yvonne R Freund, Rianna Stefanakis, Eric Easom, Xianfeng Li, Jacob J Plattner, Achim Hoerauf, Marc P Hübner
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 14, Iss 1, p e0007957 (2020)
The elimination of filarial diseases such as onchocerciasis and lymphatic filariasis is hampered by the lack of a macrofilaricidal-adult worm killing-drug. In the present study, we tested the in vivo efficacy of AN11251, a boron-pleuromutilin that ta
Externí odkaz:
https://doaj.org/article/dec6d4c0192a4b7f912f2690a17c0fac
Publikováno v:
Journal of Food Science. 85:4180-4187
A growing demand for alternative sources of texturized vegetable protein (TVP) has resulted from various factors including plant allergies, perceived health risks associated with genetically modified organisms (GMO), animal welfare beliefs, and lifes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da4379d4fcd6d9ffee09f8a9087ff2f3
https://doi.org/10.1111/1750-3841.15531
https://doi.org/10.1111/1750-3841.15531
Akademický článek
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Autor:
Robert T. Jacobs, Rianna Stefanakis, Nancy Tricoche, Eric E. Easom, Yvonne Freund, Kee Chong Lim, James H. McKerrow, David S. Carter, Christina A. Bulman, Brian M. Suzuki, Christopher S. Lunde, Pamela Berry, Judy A. Sakanari, Jacob J. Plattner, Chelsea Fischer, Sara Lustigman, Tsutomu Akama, Fernando Rock
Publikováno v:
ACS Infectious Diseases
The optimization of a series of benzimidazole–benzoxaborole hybrid molecules linked via a ketone that exhibit good activity against Onchocerca volvulus, a filarial nematode responsible for the disease onchocerciasis, also known as river blindness,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::beee7fb4c5ebfd7c32f697f2a5ce9791
https://doi.org/10.1021/acsinfecdis.9b00397
https://doi.org/10.1021/acsinfecdis.9b00397
Autor:
Rianna Stefanakis, Eric E. Easom, Jacob J. Plattner, Yvonne Freund, Erin E. Stebbins, Melissa S. Love, Pamela Berry, Jiri Gut, Christopher D. Huston, Rajiv S. Jumani, Case W. McNamara, Philip J. Rosenthal, Peter J. Miller, Christopher S. Lunde, Robert T. Jacobs, John W. Barlow, Mahmudul Hasan
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-11 (2019)
Nature Communications
Nature Communications
Cryptosporidiosis is a leading cause of life-threatening diarrhea in young children and causes chronic diarrhea in AIDS patients, but the only approved treatment is ineffective in malnourished children and immunocompromised people. We here use a drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c32813dbe54d00c74f148ff27329f781
https://doaj.org/article/9ffc28868e0b404a868e8f4e98e9bbf7
https://doaj.org/article/9ffc28868e0b404a868e8f4e98e9bbf7
Autor:
Jacob J. Plattner, Kirthana M. V. Sindhe, Roland A. Cooper, Jenny Legac, Eric E. Easom, Yvonne Freund, Yong-Kang Zhang, Wesley Wu, Philip J. Rosenthal, Joseph L. DeRisi
Publikováno v:
mBio, vol 11, iss 1
mBio, Vol 11, Iss 1, p e02640-19 (2020)
mBio
mBio, Vol 11, Iss 1 (2020)
mBio, Vol 11, Iss 1, p e02640-19 (2020)
mBio
mBio, Vol 11, Iss 1 (2020)
Benzoxaboroles are under study as potential new drugs to treat malaria. One benzoxaborole, AN13762, has potent activity and promising features, but its mechanisms of action and resistance are unknown. To gain insights into these mechanisms, we cultur
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c8e895585eb102c0d05ce9a1f2565df
https://escholarship.org/uc/item/1mq202tv
https://escholarship.org/uc/item/1mq202tv
Autor:
Robert T Jacobs, Bakela Nare, Stephen A Wring, Matthew D Orr, Daitao Chen, Jessica M Sligar, Matthew X Jenks, Robert A Noe, Tana S Bowling, Luke T Mercer, Cindy Rewerts, Eric Gaukel, Jennifer Owens, Robin Parham, Ryan Randolph, Beth Beaudet, Cyrus J Bacchi, Nigel Yarlett, Jacob J Plattner, Yvonne Freund, Charles Ding, Tsutomu Akama, Y-K Zhang, Reto Brun, Marcel Kaiser, Ivan Scandale, Robert Don
Publikováno v:
PLoS Neglected Tropical Diseases, Vol 5, Iss 6, p e1151 (2011)
BACKGROUND: Human African trypanosomiasis (HAT) is an important public health problem in sub-Saharan Africa, affecting hundreds of thousands of individuals. An urgent need exists for the discovery and development of new, safe, and effective drugs to
Externí odkaz:
https://doaj.org/article/63cd3700496b42e79618890a16e02bc3