Zobrazeno 1 - 10
of 2 265
pro vyhledávání: '"J. Piper"'
Autor:
Brendon J Yee, Nathaniel S Marshall, Collette Menadue, Edmund MT Lau, Amanda J Piper, Benjamin HM Nguyen, Olivia A McGuiness, Keith KH Wong
Publikováno v:
BMJ Open Respiratory Research, Vol 11, Iss 1 (2024)
Introduction Chronic obstructive pulmonary disease (COPD)/obstructive sleep apnoea (OSA) overlap syndrome (OVS) is associated with higher mortality compared with COPD alone in stable outpatients. However, the prognosis of patients hospitalised with a
Externí odkaz:
https://doaj.org/article/c012a42809e1498d9868e257215b7a05
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionSubstance Use Disorder (SUD) screening tools used in current practice are designed to identify SUD once patients have begun regular dangerous drug use. While these screening tools are valuable, prevention and avoidance of SUD would save c
Externí odkaz:
https://doaj.org/article/0c903b71371f49c4b57d2fe404fb0eaf
Autor:
Kaleeckal G. Harikumar, Sarah J. Piper, Arthur Christopoulos, Denise Wootten, Patrick M. Sexton, Laurence J. Miller
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-12 (2024)
Abstract Class B G protein-coupled receptors can form dimeric complexes important for high potency biological effects. Here, we apply pharmacological, biochemical, and biophysical techniques to cells and membranes expressing the prototypic secretin r
Externí odkaz:
https://doaj.org/article/03bd6139abd74708a85a68f98f562b73
Publikováno v:
Frontiers in Psychiatry, Vol 15 (2024)
IntroductionParoxetine is an older “selective” serotonin reuptake inhibitor (SSRI) that is notable for its lack of selectivity, resulting in an anticholinergic adverse-effect profile, especially among older adults (65+).MethodsParoxetine prescrip
Externí odkaz:
https://doaj.org/article/9093d6062f3b464c9e6d1a41c281d27c
Autor:
Annemarie G. Hirsch, Eric A. Wright, Cara M. Nordberg, Joseph DeWalle, Elena L. Stains, Amy L. Kennalley, Joy Zhang, Lorraine D. Tusing, Brian J. Piper
Publikováno v:
Medical Cannabis and Cannabinoids, Vol 7, Iss 1, Pp 34-43 (2024)
Introduction: Pennsylvania opened its first medical marijuana (MMJ) dispensary in 2018. Qualifying conditions include six conditions determined to have no or insufficient evidence to support or refute MMJ effectiveness. We conducted a study to descri
Externí odkaz:
https://doaj.org/article/f924674c357249b18f362ea3a595373e
Autor:
Daniel J Hellenbrand, Charles M Quinn, Zachariah J Piper, Ryan T Elder, Raveena R Mishra, Taylor L Marti, Phoebe M Omuro, Rylie M Roddick, Jae Sung Lee, William L Murphy, Amgad S Hanna
Publikováno v:
Neural Regeneration Research, Vol 19, Iss 6, Pp 1308-1317 (2024)
[INLINE:1] After spinal cord injury, there is an extensive infiltration of immune cells, which exacerbates the injury and leads to further neural degeneration. Therefore, a major aim of current research involves targeting the immune response as a tre
Externí odkaz:
https://doaj.org/article/026b4788f0ef4aa0aeaf0028d5154190
Retrospective study investigating naloxone prescribing and cost in US Medicaid and Medicare patients
Autor:
Kenneth L McCall, Brian J Piper, Christopher D Manko, Mohamed S Ahmed, Lavinia R Harrison, Srivastava A Kodavatiganti, Noelia Lugo, Jason Osei Konadu, Farrin Khan, Carrie A Massari, Tenisha K Sealey, Maame Efua Addison, Celine N Mbah, Joseph B Fraiman
Publikováno v:
BMJ Open, Vol 14, Iss 5 (2024)
Background Opioid overdoses in the USA have increased to unprecedented levels. Administration of the opioid antagonist naloxone can prevent overdoses.Objective This study was conducted to reveal the pharmacoepidemiologic patterns in naloxone prescrib
Externí odkaz:
https://doaj.org/article/9ad3d3e6eb984fe1902b899d7e35eb2b
Autor:
Zachary Cohen, Mirja Steinbrenner, Rory J. Piper, Chayanin Tangwiriyasakul, Mark P. Richardson, David J. Sharp, Ines R. Violante, David W. Carmichael
Publikováno v:
Frontiers in Neuroscience, Vol 18 (2024)
ObjectiveA third of patients with epilepsy continue to have seizures despite receiving adequate antiseizure medication. Transcranial direct current stimulation (tDCS) might be a viable adjunct treatment option, having been shown to reduce epileptic s
Externí odkaz:
https://doaj.org/article/23dfc58438714a9e832bfc57a9f943b6
Autor:
Tanya M Smith, Manish Arora, Christine Austin, Janaína Nunes Ávila, Mathieu Duval, Tze Tshen Lim, Philip J Piper, Petra Vaiglova, John de Vos, Ian S Williams, Jian-xin Zhao, Daniel R Green
Publikováno v:
eLife, Vol 12 (2024)
Studies of climate variation commonly rely on chemical and isotopic changes recorded in sequentially produced growth layers, such as in corals, shells, and tree rings, as well as in accretionary deposits—ice and sediment cores, and speleothems. Oxy
Externí odkaz:
https://doaj.org/article/cca9f2a3ff1a4ac2bae34e24435296af
Publikováno v:
BMJ Open, Vol 14, Iss 3 (2024)
Objectives This study aims to characterise oxycodone’s distribution and opioid-related overdoses in the USA by state from 2000 to 2021.Design This is an observational study.Setting More than 80 000 Americans died of an opioid overdose in 2021 as th
Externí odkaz:
https://doaj.org/article/a0b77ba74ca645949b0eb4c059a961cb