Chikungunya virus antagonizes cGAS-STING mediated type-I interferon responses by degrading cGAS

Autor: J. Pintado-Silva, J. Veloz, St Patrick Reid, Rafael Fenutria, Kenneth A. Stapleford, Ana Fernandez-Sesma, L. Carrau, D. Figueroa, Jacob S. Yount, Margarita V. Rangel, Uma Potla, T. Mutetwa, L. Zhang, Dabeiba Bernal-Rubio, Sebastian Aguirre, Tongtong Zhu, Laurence G. Webb

Publikováno v: PLoS Pathogens
PLoS Pathogens, Vol 16, Iss 10, p e1008999 (2020)

Chikungunya virus (CHIKV) is a mosquito-borne alphavirus known to cause epidemics resulting in predominantly symptomatic infections, which in rare cases cause long term debilitating arthritis and arthralgia. Significant progress has been made in unde

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http://europepmc.org/articles/PMC7591055

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Challenges on the development of a dengue vaccine: a comprehensive review of the state of the art.

Autor: Pintado Silva J; Department of Microbiology, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place, New York, NY 10029, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place, New York, NY 10029, USA., Fernandez-Sesma A; Department of Microbiology, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place, New York, NY 10029, USA.; Graduate School of Biomedical Sciences, Icahn School of Medicine at Mount Sinai, 1 Gustave Levy Place, New York, NY 10029, USA.

Publikováno v: The Journal of general virology [J Gen Virol] 2023 Mar; Vol. 104 (3).