Zobrazeno 1 - 10
of 60
pro vyhledávání: '"J. Picher"'
Autor:
Ángel J. Picher, Bettina Budeus, Oliver Wafzig, Carola Krüger, Sara García-Gómez, María I. Martínez-Jiménez, Alberto Díaz-Talavera, Daniela Weber, Luis Blanco, Armin Schneider
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-16 (2016)
Single cell genomic analysis needs DNA amplification with high fidelity and accuracy. Here, the authors devise a novel multiple displacement amplification method called TruePrime that is based in Thermus thermophilusPrimPol and Phi29 DNA polymerase,
Externí odkaz:
https://doaj.org/article/7684ce22eed44d1aa7aa7d8f45a853bc
Publikováno v:
Journal of Alzheimer's Disease Reports
Genetic factors may be involved in the onset of neurodegenerative diseases like Alzheimer's disease. In the case of the familial type, the disease is due to an inherited mutation at specific sites in three genes. Also, there are some genetic risk fac
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e537be1d7c82c3d43e3928b2be83bf82
http://europepmc.org/articles/PMC6159612
http://europepmc.org/articles/PMC6159612
Publikováno v:
Neuropsychiatrie de l'Enfance et de l'Adolescence. 64:445-454
Resume Le deficit des habiletes sociales est une problematique centrale du fonctionnement adaptatif des enfants ayant un trouble du deficit de l’attention avec hyperactivite (TDAH). Cet article propose une synthese narrative de l’etat des connais
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cc8600e47ce084659a37f3863e26ac48
https://doi.org/10.1016/j.neurenf.2016.08.004
https://doi.org/10.1016/j.neurenf.2016.08.004
Autor:
Patricia Garrido, Angel J. Picher, Esther García, Félix Hernández, Alberto Gómez-Ramos, Jesús Avila, Eduardo Soriano
Publikováno v:
Dipòsit Digital de la UB
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
Universidad de Barcelona
Recercat. Dipósit de la Recerca de Catalunya
instname
Digital.CSIC. Repositorio Institucional del CSIC
Next-generation sequencing techniques and genome-wide association study analyses have provided a huge amount of data, thereby enabling the identification of DNA variations and mutations related to disease pathogenesis. New techniques and software too
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71578b5e8df0909a5281b315c758cfac
http://hdl.handle.net/2445/120336
http://hdl.handle.net/2445/120336
Publikováno v:
Nucleic Acids Research
Digital.CSIC. Repositorio Institucional del CSIC
instname
Digital.CSIC. Repositorio Institucional del CSIC
instname
Full genome sequencing of bacterial genomes has revealed the presence of numerous genes encoding family X DNA polymerases. These enzymes play a variety of biological roles and, accordingly, display often striking functional differences. Here we repor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e5c09737c644f0ca9c4390625bb9e8
http://europepmc.org/articles/PMC3874185
http://europepmc.org/articles/PMC3874185
Autor:
Nigel C. Brissett, Gavin C. Fox, Timothy R. Dafforn, Andrew Green, Robert S. Pitcher, Angel J. Picher, Raquel Juárez, Luis Blanco, Aidan J. Doherty
Publikováno v:
Science. 318:456-459
Nonhomologous end joining (NHEJ) is a critical DNA double-strand break (DSB) repair pathway required to maintain genome stability. Many prokaryotes possess a minimalist NHEJ apparatus required to repair DSBs during stationary phase, composed of two c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0a6624f6be1265f403c43b3098f60593
https://doi.org/10.1126/science.1145112
https://doi.org/10.1126/science.1145112
Autor:
D.A. de Luis, A. Cano, Boixeda D, Rocío Aller, J. Picher, S. Garcia-Rull, José Luis Moya, Víctor Moreira
Publikováno v:
Digestive Diseases and Sciences. 44:1243-1248
The aim of this study was to study theprevalence of hepatopulmonary syndrome (HPS) incirrhotic patients, comparing the results obtained usingcontrast transthoracic echocardiography (CTTE) andcontrast transesophageal echocardiography (CTEE) in thedemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fc55d46387fabb8a7a1cd22206fc8997
https://doi.org/10.1023/a:1026657114256
https://doi.org/10.1023/a:1026657114256
Autor:
Angel J. Picher, Luis Blanco
Publikováno v:
DNA repair. 6(12)
Pol lambda is a DNA repair enzyme with a high affinity for dNTPs, an intrinsic dRP lyase activity, a BRCT domain involved in interactions with NHEJ factors, and also capable to interact with the PCNA processivity factor. Based on this potential, Pol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8f3b96ca0c3ce640dadbbc9ac2edf6dc
https://pubmed.ncbi.nlm.nih.gov/17686665
https://pubmed.ncbi.nlm.nih.gov/17686665
Autor:
Raquel Juárez, Luis Blanco, D Thompson, Paula B. Andrade, Nigel C. Brissett, Aidan J. Doherty, Robert S. Pitcher, Gavin C. Fox, Angel J. Picher
Publikováno v:
Journal of molecular biology. 366(2)
Non homologous end-joining (NHEJ)-mediated repair of DNA double-strand breaks in prokaryotes requires Ku and a specific multidomain DNA ligase (LigD). We present crystal structures of the primase/polymerisation domain (PolDom) of Mycobacterium tuberc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9446f8606fbd245563cf6e19ed9f330
https://pubmed.ncbi.nlm.nih.gov/17174332
https://pubmed.ncbi.nlm.nih.gov/17174332
Autor:
Lars C. Pedersen, Angel J. Picher, Miguel Garcia-Diaz, Katarzyna Bebenek, Luis Blanco, Thomas A. Kunkel
Publikováno v:
Nucleic Acids Research
DNA polymerase lambda (Pol l) is one of severalDNA polymerases suggested to participate in baseexcision repair (BER), in repair of broken DNA endsand in translesion synthesis. It has been proposedthat the nature of the DNA intermediates partlydetermi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0715449636b0b8e05b26afbf55900c1
https://pubmed.ncbi.nlm.nih.gov/16807316
https://pubmed.ncbi.nlm.nih.gov/16807316