Zobrazeno 1 - 10
of 376
pro vyhledávání: '"J. Philp"'
Autor:
Yuhei Takaya, Louis-Philippe Caron, Eric Blake, François Bonnardot, Nicolas Bruneau, Joanne Camp, Johnny Chan, Paul Gregory, Jhordanne J. Jones, Namyoung Kang, Philip J. Klotzbach, Yuriy Kuleshov, Marie-Dominique Leroux, Julia F. Lockwood, Hiroyuki Murakami, Akio Nishimura, Dushmanta R. Pattanaik, Tom J. Philp, Yohan Ruprich-Robert, Ralf Toumi, Frédéric Vitart, Seonghee Won, Ruifen Zhan
Publikováno v:
Tropical Cyclone Research and Review, Vol 12, Iss 3, Pp 182-199 (2023)
Seasonal tropical cyclone (TC) forecasting has evolved substantially since its commencement in the early 1980s. However, present operational seasonal TC forecasting services still do not meet the requirements of society and stakeholders: current oper
Externí odkaz:
https://doaj.org/article/384a180bb7484a788879a75df5ad9f27
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract We present a mathematical model of key glucose metabolic pathways in two cells of the human retina: the rods and the retinal pigmented epithelium (RPE). Computational simulations of glucose transporter 1 (GLUT1) inhibition in the model accur
Externí odkaz:
https://doaj.org/article/4f15479cb3934309acdb85e39f3353bd
Autor:
Sara Bisetto, Megan C. Wright, Romana A. Nowak, Angelo C. Lepore, Tejvir S. Khurana, Emanuele Loro, Nancy J. Philp
Publikováno v:
iScience, Vol 22, Iss , Pp 507-518 (2019)
Summary: Lactate produced by muscle during high-intensity activity is an important end product of glycolysis that supports whole body metabolism. The lactate shuttle model suggested that lactate produced by glycolytic muscle fibers is utilized by oxi
Externí odkaz:
https://doaj.org/article/ce448164eafd4ade9a76cd5e99222414
Autor:
Petra Hanson, Christopher J. Philp, Harpal S. Randeva, Sean James, J. Paul O’Hare, Thomas Meersmann, Galina E. Pavlovskaya, Thomas M. Barber
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
BACKGROUND. Dietary sodium intake mismatches urinary sodium excretion over prolonged periods. Our aims were to localize and quantify electrostatically bound sodium within human skin using triple-quantum–filtered (TQF) protocols for MRI and magnetic
Externí odkaz:
https://doaj.org/article/d89ea2b453404ee9b0b046ce7f0ce199
Autor:
Amanda L. Tatler, Christopher J. Philp, Michael R. Hill, Sam Cox, Andrew M. Bullock, Anthony Habgood, Alison John, Robert Middlewick, Katherine E. Stephenson, Amanda T. Goodwin, Charlotte K. Billington, Reuben D. O’Dea, Simon R. Johnson, Bindi S. Brook
Publikováno v:
L284
L271
L271
Airway remodeling occurs in chronic asthma leading to increased airway smooth muscle (ASM) mass and extracellular matrix (ECM) deposition. Although extensively studied in murine airways, studies report only selected larger airways at one time-point m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::83f29c15e63a47bc73bf1e9eeeda7b2d
https://doi.org/10.1152/ajplung.00034.2022
https://doi.org/10.1152/ajplung.00034.2022
Publikováno v:
Current Opinion in Ophthalmology. 33:219-227
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0207ffc324452b252b519807aa2bb64
https://doi.org/10.1097/icu.0000000000000840
https://doi.org/10.1097/icu.0000000000000840
Supplementary Figure 1 from Monocarboxylate Transporter 4 Regulates Maturation and Trafficking of CD147 to the Plasma Membrane in the Metastatic Breast Cancer Cell Line MDA-MB-231
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::32dce6b2ba6102bef94e7dfc131ed854
https://doi.org/10.1158/0008-5472.22368140.v1
https://doi.org/10.1158/0008-5472.22368140.v1
Metastatic cancer cells increase glucose consumption and metabolism via glycolysis, producing large quantities of lactate. Recent work has shown that lactate efflux is mediated by monocarboxylate transporters (MCT), which are composed of a catalytic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04616675e3d08ed9d1a1dabad4ef9d8d
https://doi.org/10.1158/0008-5472.c.6495830.v1
https://doi.org/10.1158/0008-5472.c.6495830.v1
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 7; Pages: 6716
bioRxiv
bioRxiv
LC3b (Map1lc3b) plays an essential role in canonical autophagy and is one of several components of the autophagy machinery that mediates non-canonical autophagic functions. Phagosomes are often associated with lipidated LC3b, to pro-mote phagosome ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::22f222ffebe44cdcebabdd7925fe04fe
https://doi.org/10.1101/2023.03.14.532586
https://doi.org/10.1101/2023.03.14.532586
Autor:
Anuradha Dhingra, Brent A. Bell, Neal S. Peachey, Lauren L. Daniele, Juan Reyes-Reveles, Rachel C. Sharp, Bokkyoo Jun, Nicolas G. Bazan, Janet R. Sparrow, Hye Jin Kim, Nancy J. Philp, Kathleen Boesze-Battaglia
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 12 (2018)
Like other neurons, retinal cells utilize autophagic pathways to maintain cell homeostasis. The mammalian retina relies on heterophagy and selective autophagy to efficiently degrade and metabolize ingested lipids with disruption in autophagy associat
Externí odkaz:
https://doaj.org/article/eb1e6a537f84441ebe0344c9f1b55781