Zobrazeno 1 - 10
of 231
pro vyhledávání: '"J. Philip McCoy"'
Autor:
Ahmad Shaikh, Arunakumar Gangaplara, Abdoul Kone, Katherine Almengo, Mariama D. Kabore, Mohamed A.E. Ali, Xin Xu, Ankit Saxena, Maria Lopez-Ocasio, J. Philip McCoy, Courtney D. Fitzhugh
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
Haploidentical hematopoietic cell transplantation (haplo-HCT) is associated with an increased risk of allograft rejection. Here, we employed a major histocompatibility complex (MHC)-mismatched allogeneic HCT (allo-HCT) murine model to better understa
Externí odkaz:
https://doaj.org/article/24e35174d94942e4b4ebfeee39393ccf
Autor:
Wen-Wei Zhang, Subir Karmakar, Sreenivas Gannavaram, Ranadhir Dey, Patrick Lypaczewski, Nevien Ismail, Abid Siddiqui, Vahan Simonyan, Fabiano Oliveira, Iliano V. Coutinho-Abreu, Thiago DeSouza-Vieira, Claudio Meneses, James Oristian, Tiago D. Serafim, Abu Musa, Risa Nakamura, Noushin Saljoughian, Greta Volpedo, Monika Satoskar, Sanika Satoskar, Pradeep K. Dagur, J. Philip McCoy, Shaden Kamhawi, Jesus G. Valenzuela, Shinjiro Hamano, Abhay R. Satoskar, Greg Matlashewski, Hira L. Nakhasi
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-14 (2020)
Here, the authors engineer an attenuated knock-out Leishmania (LmCen −/−) vaccine that is safe in immunocompromised mice and induces an immune response and protection similar to leishmanization with wild-type Leishmania. Since LmCen −/− is an
Externí odkaz:
https://doaj.org/article/a50605a064c049859dfcd1fb76a10dad
Autor:
Yvonne Baumer, Cristhian A. Gutierrez-Huerta, Ankit Saxena, Pradeep K. Dagur, Steven D. Langerman, Kosuke Tamura, Joniqua N. Ceasar, Marcus R. Andrews, Valerie Mitchell, Billy S. Collins, Quan Yu, Heather L. Teague, Martin P. Playford, Christopher K. E. Bleck, Nehal N. Mehta, J. Philip McCoy, Tiffany M. Powell-Wiley
Publikováno v:
Journal of Translational Medicine, Vol 18, Iss 1, Pp 1-14 (2020)
Abstract Background Cardiovascular disease (CVD) is the leading cause of death in the world. Given the role of immune cells in atherosclerosis development and progression, effective methods for characterizing immune cell populations are needed, parti
Externí odkaz:
https://doaj.org/article/56a11a9a7e2e4a0a87399e07652ca36d
Autor:
Deepali K. Bhat, Purevdorj B. Olkhanud, Arunakumar Gangaplara, Fayaz Seifuddin, Mehdi Pirooznia, Angélique Biancotto, Giovanna Fantoni, Corinne Pittman, Berline Francis, Pradeep K. Dagur, Ankit Saxena, J. Philip McCoy, Ruth M. Pfeiffer, Courtney D. Fitzhugh
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Haploidentical hematopoietic stem cell transplantation (haplo-HSCT) is a widely available curative option for patients with sickle cell disease (SCD). Our original non-myeloablative haplo-HSCT trial employing post-transplant (PT) cyclophosphamide had
Externí odkaz:
https://doaj.org/article/24e70ed7cf154c4e8c2147f41d584da8
Autor:
Heather L. Teague, PhD, Nevin J. Varghese, BS, Lam C. Tsoi, PhD, Amit K. Dey, MD, Michael S. Garshick, MD, Joanna I. Silverman, BA, Yvonne Baumer, PhD, Charlotte L. Harrington, BA, Erin Stempinski, MS, Youssef A. Elnabawi, BS, Pradeep K. Dagur, PhD, Kairong Cui, PhD, Ilker Tunc, PhD, Fayaz Seifuddin, MSc, Aditya A. Joshi, MD, Elena Stansky, BS, Monica M. Purmalek, BS, Justin A. Rodante, PA, Andrew Keel, DNP, Tarek Z. Aridi, BS, Carmelo Carmona-Rivera, PhD, Gregory E. Sanda, BS, Marcus Y. Chen, MD, Mehdi Pirooznia, MD, PhD, J. Philip McCoy, Jr., PhD, Joel M. Gelfand, MD, Keji Zhao, PhD, Johann E. Gudjonsson, MD, PhD, Martin P. Playford, PhD, Mariana J. Kaplan, MD, Jeffrey S. Berger, MD, Nehal N. Mehta, MD
Publikováno v:
JACC: Basic to Translational Science, Vol 4, Iss 1, Pp 1-14 (2019)
Summary: Psoriasis is an inflammatory skin disease associated with increased cardiovascular risk and serves as a reliable model to study inflammatory atherogenesis. Because neutrophils are implicated in atherosclerosis development, this study reports
Externí odkaz:
https://doaj.org/article/58c2052d89974c20b205441c9749fd1d
Autor:
Meghali Goswami, Katherine E. Lindblad, Rahul Ramraj, Pradeep K. Dagur, Julie Thompson, J. Philip McCoy, Christopher S. Hourigan
Publikováno v:
Clinical Hematology International, Vol 2, Iss 3 (2020)
Externí odkaz:
https://doaj.org/article/5e41bc529d004b92acfcb643353dcee3
Autor:
Anil Kumar Jaiswal, Sangeet Makhija, Natalie Stahr, Maninder Sandey, Amol Suryawanshi, Ankit Saxena, Pradeep K. Dagur, J. Philip McCoy, Stewart J. Levine, Amarjit Mishra
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Proliferation of dendritic cell (DC)—restricted progenitor cells in bone marrow compartment is tightly regulated at steady state and responds to multiple tissue-specific triggers during disturbed homeostasis such as obesity. DCs in the lung stem fr
Externí odkaz:
https://doaj.org/article/ac3586ca0a3a42f0adc320c4da9ef968
Autor:
Umesh D. Wankhade, Ji-Hyeon Lee, Pradeep K. Dagur, Hariom Yadav, Michael Shen, Weiping Chen, Ashok B. Kulkarni, J. Philip McCoy, Toren Finkel, Aaron M. Cypess, Sushil G. Rane
Publikováno v:
Molecular Metabolism, Vol 16, Iss , Pp 160-171 (2018)
Objective: Beige/brite adipose tissue displays morphological characteristics and beneficial metabolic traits of brown adipose tissue. Previously, we showed that TGF-β signaling regulates the browning of white adipose tissue. Here, we inquired whethe
Externí odkaz:
https://doaj.org/article/0a4593b69adf4e4488d472817a18ddae
Autor:
Lai Wei, Baoying Liu, Jingsheng Tuo, Defen Shen, Ping Chen, Zhiyu Li, Xunxian Liu, Jia Ni, Pradeep Dagur, H. Nida Sen, Shayma Jawad, Diamond Ling, Stanley Park, Sagarika Chakrabarty, Catherine Meyerle, Elvira Agron, Frederick L. Ferris, 3rd, Emily Y. Chew, J. Philip McCoy, Emily Blum, Peter J. Francis, Michael L. Klein, Robyn H. Guymer, Paul N. Baird, Chi-Chao Chan, Robert B. Nussenblatt
Publikováno v:
Cell Reports, Vol 2, Iss 5, Pp 1151-1158 (2012)
Age-related macular degeneration (AMD) is the leading cause of irreversible blindness in the elderly population worldwide. Although recent studies have demonstrated strong genetic associations between AMD and SNPs in a number of genes, other modes of
Externí odkaz:
https://doaj.org/article/e23c7e2262554e63af866f95e950266c
Autor:
Xingmin Feng, Phillip Scheinberg, Angelique Biancotto, Olga Rios, Sarah Donaldson, Colin Wu, Haiyun Zheng, Kazuya Sato, Danielle M. Townsley, J. Philip McCoy, Neal S. Young
Publikováno v:
Haematologica, Vol 99, Iss 9 (2014)
We recently reported that rabbit antithymocyte globulin was markedly inferior to horse antithymocyte globulin as a primary treatment for severe aplastic anemia. Here we expand on our findings in this unique cohort of patients. Rabbit antithymocyte gl
Externí odkaz:
https://doaj.org/article/a73b6e8c82464fcb8a1cc705bf2215da