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Thitium nuclear magnetic resonance spectroscopy. Part 13 [ref. (1)]. Tritium labelled neurochemicals
Autor:
John A. Elvidge, David C. Warrell, J. Philip Kitcher, E. Anthony Evans, James P. Bloxsidge, John R. Jones, Marion Gower
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 18:1141-1165
A series of 50 neurochemicals, important for the investigation of neurotransmission processes, has been labelled with tritium, using in all 8 methods. Tritium nuclear magnetic resonance spectroscopy has been employed to determine the positions and ex
Autor:
James P. Bloxsidge, David C. Warrell, John R. Jones, J. Philip Kitcher, E. Anthony Evans, John A. Elvidge
Publikováno v:
Organic Magnetic Resonance. 15:214-217
The complete analysis of the tritium distribution in tritiated methyl groups in labelled compounds is achieved by a direct method for the first time, through 3H NMR spectroscopy aided by resolution enhancement.
Publikováno v:
Journal of Labelled Compounds and Radiopharmaceuticals. 20:277-284
N-Succinimidyl propionate [NSP] was synthesised and characterised as a pale yellow waxy solid. Rates of hydrolysis in buffers range pH 5–9 were determined. Optimum conditions for reaction with lysine were within the range pH 7 to 8. A protein, whea