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Abnormal neutrophil signature in the blood and pancreas of presymptomatic and symptomatic type 1 diabetes

Autor: Jay M. Sosenko, D. J. Becker, Kevan C. Herold, E. Leschek, James W. Thomas, Francesco Dotta, Jeffrey L. Mahon, K. Nanto-Salonen, Diane K. Wherrett, Lisa M. Spain, Andrew Muir, Polly J. Bingley, Massimo Trucco, Jeffrey P. Krischer, S. E. Gitelman, Alessandra Mandelli, Mark S. Anderson, Sarah J. Richardson, Peter S. Linsley, Riccardo Bonfanti, Eleonora Bianconi, George S. Eisenbarth, M. Siegelman, J. Peyman, Angela Stabilini, M. Redondo, Bernhard J. Hering, Richard A. Insel, Maurizio De Pellegrin, Franco Meschi, Francesca Ragogna, Mark A. Clements, Lars Krogvold, Mark Peakman, Alberto Pugliese, J. Blum, William E. Russell, P. Chase, Pia Leete, Anette-Gabriele Ziegler, Mark A. Atkinson, Jane H. Buckner, Andrea Rigamonti, Tihamer Orban, Laura Nigi, Philip Raskin, Guido Sebastiani, Louis H. Philipson, Linda A. DiMeglio, Clara Bonura, Manuela Battaglia, Jay S. Skyler, David A. Baidal, Giulio Frontino, Emanuele Bosi, Matthew J. Dufort, Andrea Valle, William E. Winter, Peter A. Gottlieb, C. G. Fathman, Helena Elding Larsson, Robin Goland, Michael J. Clare-Salzler, M. G. Roncarolo, Raphael Clynes, Peter A. Antinozzi, Andrea K. Steck, Mikael Knip, Olli Simell, R. Parkman, Bart O. Roep, Desmond A. Schatz, Henry Rodriguez, Nicola Lo Buono, John M. Wentworth, Andrea Laurenzi, Francesca Mancarella, P. Savage, Jennifer B. Marks, G. Grave, Paola M.V. Rancoita, Federica Vecchio, Åke Lernmark, Darrell M. Wilson, Noel G. Morgan, Thomas W.H. Kay, Francine R. Kaufman, Federica Cugnata, Christophe Benoist, Susan Geyer, Peter G. Colman, Mark D. Pescovitz, Robert S. Sherwin, Gerald T. Nepom, John E. Wagner, Antoinette Moran, Knut Dahl-Jørgensen, Jerry P. Palmer, Kasia Bourcier, Wayne V. Moore, Carla J. Greenbaum, Pauline Grogan

BACKGROUND. Neutrophils and their inflammatory mediators are key pathogenic components in multiple autoimmune diseases, while their role in human type 1 diabetes (T1D), a disease that progresses sequentially through identifiable stages prior to the c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bee5d8b12a49d70a6a58dc2174c69799

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Global expression analysis of the fibroblast transcriptional response to TGFbeta

Autor: H, Gardner, D, Strehlow, L, Bradley, R, Widom, A, Farina, A, de Fougerolles, J, Peyman, V, Koteliansky, J H, Korn

Publikováno v: Clinical and experimental rheumatology. 22(3 Suppl 33)

Transforming Growth Factor-beta (TGFbeta) is the predominant cytokine in all forms of fibrotic reactions. As well as being secreted by immune modulators of fibrosis such as macrophages, it is involved in an autocrine feedback loop of fibroblast stimu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::898600ed50873afd23b44373c56e6e80
https://pubmed.ncbi.nlm.nih.gov/15344598

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Akademický článek

A Data-driven Method for Crowd Simulation using a Holonification Model

Autor: J. Peymanfard, N. Mozayani

Publikováno v: Journal of Artificial Intelligence and Data Mining, Vol 7, Iss 3, Pp 403-409 (2019)

In this paper, we present a data-driven method for crowd simulation with holonification model. With this extra module, the accuracy of simulation will increase and it generates more realistic behaviors of agents. First, we show how to use the concept

Externí odkaz: https://doaj.org/article/03e3ceb705514d2793d422874d2461f7

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Akademický článek

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Akademický článek

Antibacterial activity of the brown algae (Sargassum glaucescens) ethanolic and aqueous extracts from Chabahar coasts, Oman Sea, Iran

Autor: J. Peymani; A. Gharaei email ; M. Ghaffari; A. Taheri

Publikováno v: ‬‭Majallah-i ̒Ilmī-i Shīlāt-i Īrān, Vol 22, Iss 4, Pp 13-20 (2014)

The widespread uses of antibiotics have been resulted in resistant strains of microorganisms and increasing of worldwide antibiotic resistance. Thus the investigations on new natural antibacterial agents as new drugs are important. According to the p

Externí odkaz: https://doaj.org/article/4d9b612faaba4603849607cf40d15067

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