Zobrazeno 1 - 10
of 13
pro vyhledávání: '"J. Peter Clayton"'
Autor:
Walter J. Smith, Edward K. Chess, Michael L. Vieira, Michal Sabat, Robin P. Attrill, John H. C. Nayler, Kirk A. Ashline, Jeremy R. Everett, David E. Pereira, J. Peter Clayton, Ernest A. Cutmore, John W. Tyler
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 2. :1559
High-field nuclear magnetic resonance spectroscopy, mass spectrometry, infrared spectroscopy, and ultraviolet spectroscopy were used to determine the structures of two novel degradation productions of the penicillins sodium nafcillin (1) and sodium o
Publikováno v:
Tetrahedron Letters. 21:881-884
A new antibiotic, pseudomonic acid C (2a), has been isolated from fermentations of the strain of Pseudomonas fluorescens which produces the known and structurally similar antibiotics pseudomonic acids A (1a) and B (1c).
Publikováno v:
J. Chem. Soc., Perkin Trans. 1. :22-25
The action of methyl iodide and strong anhydrous base on methyl penicillanate or its 6α-bromo-derivative leads to S-methylation and cleavage of both thiazolidine and β-lactam rings, but with methyl 6,6-dibromopenicillanate the β-lactam system rema
Publikováno v:
Chemischer Informationsdienst. 5
Autor:
Peter H. Bentley, J. Peter Clayton
Publikováno v:
J. Chem. Soc., Chem. Commun.. :278-279
Benzyl 6-isocyanopenicillanate (2a), has been utilised in the preparation of 6α-substituted penicillins.
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :561
The configuration of the double bond in pseudomonic acid A (1a) is shown to be E by comparison of the spectroscopic properties of its methyl ester (1b) with those of methyl isopseudomonate A (2) obtained from (1b) by photolysis. Ozonolysis of methyl
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1352
The cyclisation of 3-mercapto-1,2,4-triazole (1a) and 2-mercaptoimidazole (7) with diethyl ethoxymethylenemalonate is shown to produce 6-ethoxycarbonyl[1,2,4]triazolo[3,2-b][1, 3]thiazin-5-one (2a) and 6-ethoxycarbonylimidazolo[2,1-b][1,3]thiazin-5-o
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :2827
A third and minor antibiotic component, designated pseudomonic acid C (1a),2 has been isolated from cultures of the strain Pseudomonas fluorescens NCIB 10586 which produced the structurally related pseudomonic acid A (2a) and B (3). The structure and
Publikováno v:
Journal of the Chemical Society, Perkin Transactions 1. :1347
The product obtained by treating 6-ethoxycarbonyl-7-hydroxypyrazolo[1,5-a]pyrimidine (2a) with ethyl iodide is shown by X-ray analysis to be 6-ethoxycarbonyl-4-ethylpyrazolo[1,5-a]pyrimidin-7(4H)-one (3a). When 3-amino-1,2,4-triazole (5a) was cyclise
Publikováno v:
Journal of the Chemical Society, Chemical Communications. :500
Condensation of 1,4-dichlorobut-3-en-2-one with malonic esters gives the corresponding Knoevenagel adducts which may be cyclised directly to thiophen-3-malonic esters or their selenophen analogues.