Zobrazeno 1 - 10
of 101
pro vyhledávání: '"J. Perper"'
Autor:
Mark Cornebise, C. Nickerson-Nutter, Brian M. Dolinski, Stuart J. Perper, Steve Adams, Alan Gill, Diane R Leone, Doreen Lepage, Keith Giza, R. B. Pepinsky, L. L. Chen, Eric T. Whalley, Roy R. Lobb, K. Wortham, Petter Russell C, Daniel Scott, Wen-Cherng Lee, A. Chakraborty
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 312:742-750
Integrin alpha4beta1 plays an important role in inflammatory processes by regulating the migration of leukocytes into inflamed tissues. Previously, we identified BIO5192 [2(S)-{[1-(3,5-dichloro-benzenesulfonyl)-pyrrolidine-2(S)-carbonyl]-amino}-4-[4-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9daccf593e3e23af58b9231b1c686183
https://doi.org/10.1124/jpet.104.075648
https://doi.org/10.1124/jpet.104.075648
Autor:
Roy R. Lobb, Mark Cornebise, Russell C. Petter, C. Nickerson-Nutter, K. Wortham, Doreen Lepage, R. B. Pepinsky, Wen-Cherng Lee, Steve Adams, L. L. Chen, Daniel Scott, J. C. Spell, Brian M. Dolinski, Alan Gill, W. Yang, Keith Giza, Stuart J. Perper, Eric T. Whalley, Diane R Leone
Publikováno v:
Journal of Pharmacology and Experimental Therapeutics. 305:1150-1162
Integrin alpha 4 beta 1 plays an important role in inflammatory processes by regulating the migration of lymphocytes into inflamed tissues. Here we evaluated the biochemical, pharmacological, and pharmacodynamic properties and efficacy in experimenta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e08a2c9025a531d25a49df899c5a776c
https://doi.org/10.1124/jpet.102.047332
https://doi.org/10.1124/jpet.102.047332
Publikováno v:
European Journal of Immunology. 22:1673-1679
DAB486IL-2 is an interleukin-2 receptor-specific cytotoxin which selectively targets and kills cells which bear the high-affinity form of the IL-2 receptor. Since elimination of activated T lymphocytes may be useful in the treatment of rheumatoid art
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19dea7ec7665847bbc1911fd4a4baa16
https://doi.org/10.1002/eji.1830220702
https://doi.org/10.1002/eji.1830220702
Autor:
Shawn Weng, Cindy Gao, Gerald J. Atkins, Timothy S. Zheng, Luis Rajman, Keith Giza, Stuart J. Perper, David M. Findlay, Thomas Crowell, Lihe Su, Leticia Tarilonte, Beth Browning, Linda C. Burkly, Laura Runkel, Henry Hess, Martin L. Scott
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 177(4)
TNF-like weak inducer of apoptosis (TWEAK) is a TNF family member with pleiotropic effects on a variety of cell types, one of which is the induction of proinflammatory cytokines by synovial fibroblasts derived from rheumatoid arthritis (RA) patients.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1187ce74ac7a63bfa3b5e6dfce11c96
https://pubmed.ncbi.nlm.nih.gov/16888023
https://pubmed.ncbi.nlm.nih.gov/16888023
Autor:
Cheryl Nickerson-Nutter, Irene Sizing, Jeffrey L. Browning, Stuart J. Perper, Apinya Ngam-ek, Jennifer L. Gommerman, Keith Giza
Publikováno v:
The Journal of clinical investigation. 112(5)
In studies using genetically deficient mice, a role for the lymphotoxin (LT) system in the pathogenesis of experimental autoimmune encephalomyelitis (EAE) has remained controversial. Here, we have reassessed this conclusion by using a fusion protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b70a1867fabee8c7a2d152477af9d343
https://pubmed.ncbi.nlm.nih.gov/12952924
https://pubmed.ncbi.nlm.nih.gov/12952924
Autor:
Cheryl Nickerson-Nutter, Bradley E. Theien, Eric T. Whalley, Carol L. Vanderlugt, Daniel Scott, Stuart J. Perper, Mark Cornebise, Stephen D. Miller
Publikováno v:
Blood. 102(13)
Interaction of very late antigen-4 (VLA-4) with its ligand vascular cell adhesion molecule-1 (VCAM-1) is required for central nervous system (CNS) migration of encephalitogenic T cells in relapsing experimental autoimmune encephalomyelitis (R-EAE). A
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c1d2aa6bfed9ace52e82743ddfa9a78
https://pubmed.ncbi.nlm.nih.gov/12933585
https://pubmed.ncbi.nlm.nih.gov/12933585
Autor:
P, Shapshak, K A, Crandall, K Q, Xin, K, Goodkin, R K, Fujimura, W, Bradley, C B, McCoy, I, Nagano, M, Yoshioka, C, Petito, N C, Sun, A K, Srivastava, N, Weatherby, R, Stewart, S, Delgado, A, Matthews, R, Douyon, K, Okuda, J, Yang, B T, Zhangl, X R, Cao, S, Shatkovsky, J B, Fernandez, S M, Shah, J, Perper
Publikováno v:
Advances in experimental medicine and biology. 402
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::452e81be8d3aa84b40871258d6ca191d
https://pubmed.ncbi.nlm.nih.gov/8787658
https://pubmed.ncbi.nlm.nih.gov/8787658
Publikováno v:
Suicidelife-threatening behavior. 26(3)
The psychiatric sequelae of loss of a family member to suicide were evaluated in parents and siblings of adolescent suicide victims and controls, who were followed up to 3 years after the suicide. Siblings did not show an increased risk for the devel
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a9c26561ccf7be5a9a4726882820dc40
https://pubmed.ncbi.nlm.nih.gov/9357087
https://pubmed.ncbi.nlm.nih.gov/9357087
Autor:
Robert K. Fujimura, Silvia Delgado, Richard Douyon, Paul Shapshak, A. K. Srivastava, W. Bradley, Kenji Okuda, S. M. Shah, J. B. Fernandez, Carol K. Petito, M. Yoshioka, N. C. J. Sun, Karl Goodkin, J. Yang, A. Matthews, J. Perper, Keith A. Crandall, Renee V. Stewart, B. T. Zhangl, Clyde B. McCoy, I. Nagano, Ke-Qin Xin, Norman L. Weatherby, S. Shatkovsky, X. R. Cao
Publikováno v:
Advances in Experimental Medicine and Biology ISBN: 9781461380382
HIV Associated Dementia (HAD) and peripheral neuropathy result from HIV-1 infection and several parameters impact on their initiation and course. These parameters include properties of the virus such as sequence heterogeneity of the envelope protein
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::267f2ea8004b519acfe2be96b75ae28b
https://doi.org/10.1007/978-1-4613-0407-4_23
https://doi.org/10.1007/978-1-4613-0407-4_23
Publikováno v:
Proceedings. Symposium on Computer Applications in Medical Care.
We propose and have implemented a program, called "Real Problems", for the authoring of simulated patient encounters. This program uses a layered database approach to separate the unchanging sections of the program from the more patient-specific sect
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0718405678bc2a2fea11647cf0061563
https://pubmed.ncbi.nlm.nih.gov/1482963
https://pubmed.ncbi.nlm.nih.gov/1482963