Zobrazeno 1 - 10
of 148
pro vyhledávání: '"J. Pedro Simas"'
Autor:
Kiran Iqbal Masood, Shama Qaiser, Syed Hani Abidi, Erum Khan, Syed Faisal Mahmood, Areeba Hussain, Zara Ghous, Khekahsan Imtiaz, Natasha Ali, Muhammad Hasan, Haris Ali Memon, Maliha Yameen, Shiza Ali, Sadaf Baloch, Gulzar Lakhani, Paula M. Alves, Najeeha Talat Iqbal, Kumail Ahmed, Junaid Iqbal, Zulfiqar A. Bhutta, Rabia Hussain, Martin Rottenberg, J. Pedro Simas, Marc Veldhoen, Kulsoom Ghias, Zahra Hasan
Publikováno v:
BMC Infectious Diseases, Vol 23, Iss 1, Pp 1-14 (2023)
Abstract Background Protection against SARS-CoV-2 is mediated by humoral and T cell responses. Pakistan faced relatively low morbidity and mortality from COVID-19 through the pandemic. To examine the role of prior immunity in the population, we studi
Externí odkaz:
https://doaj.org/article/daab1b9127084bd1ae6c4561d555d5e2
Autor:
Shijun Li, Mengbo Wang, Nicholas Van Sciver, Agnieszka Szymula, Vinayak Sadasivam Tumuluri, Athira George, Akshaya Ramachandran, Komal Raina, Catarina N Costa, Bo Zhao, Majid Kazemian, J Pedro Simas, Kenneth M Kaye
Publikováno v:
PLoS Pathogens, Vol 20, Iss 1, p e1011907 (2024)
Kaposi's sarcoma herpesvirus (KSHV) is a leading cause of malignancy in AIDS and current therapies are limited. Like all herpesviruses, KSHV infection can be latent or lytic. KSHV latency-associated nuclear antigen (LANA) is essential for viral genom
Externí odkaz:
https://doaj.org/article/b33daf9f0dca4183849c72279d8b02b9
Autor:
Ana Fraga, Andreia F. Mósca, Diana Moita, J. Pedro Simas, Helena Nunes-Cabaço, Miguel Prudêncio
Publikováno v:
Frontiers in Cellular and Infection Microbiology, Vol 13 (2023)
Coronavirus disease 2019 (COVID-19) and malaria, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and Plasmodium parasites, respectively, share geographical distribution in regions where the latter disease is endemic, leading to
Externí odkaz:
https://doaj.org/article/51a27339265c46fa940b8c23594741c1
Autor:
Zahra Hasan, Kiran Iqbal Masood, Shama Qaiser, Erum Khan, Areeba Hussain, Zara Ghous, Unab Khan, Maliha Yameen, Imran Hassan, Muhammad Imran Nasir, Muhammad Farrukh Qazi, Haris Ali Memon, Shiza Ali, Sadaf Baloch, Zulfiqar A. Bhutta, Marc Veldhoen, J. Pedro Simas, Syed Faisal Mahmood, Kulsoom Ghias, Rabia Hussain
Publikováno v:
Health Science Reports, Vol 6, Iss 9, Pp n/a-n/a (2023)
Abstract Background and Aims COVID‐19 vaccinations have reduced morbidity and mortality from the disease. Antibodies against severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) have been associated with immune protection. Seroprevalenc
Externí odkaz:
https://doaj.org/article/565f488e64124230b6d07d32778da326
Autor:
Agnieszka Szymula, Gabriela Samayoa-Reyes, Sidney Ogolla, Bing Liu, Shijun Li, Athira George, Nicholas Van Sciver, Rosemary Rochford, J. Pedro Simas, Kenneth M. Kaye
Publikováno v:
Cell Reports, Vol 42, Iss 7, Pp 112767- (2023)
Summary: Kaposi’s sarcoma herpesvirus (KSHV) establishes lifelong infection and persists in latently infected B cells. Paradoxically, in vitro B cell infection is inefficient, and cells rapidly die, suggesting the absence of necessary factor(s). KS
Externí odkaz:
https://doaj.org/article/c1d1cd8cfd444ee9bb32c010a02070aa
Autor:
Muhammad Hasan, Bushra Moiz, Shama Qaiser, Kiran Iqbal Masood, Zara Ghous, Areeba Hussain, Natasha Ali, J Pedro Simas, Marc Veldhoen, Paula Alves, Syed Hani Abidi, Kulsoom Ghias, Erum Khan, Zahra Hasan
Publikováno v:
PLoS ONE, Vol 17, Iss 8, p e0271259 (2022)
IntroductionAn estimated 1.5 million cases were reported in Pakistan until 23 March, 2022. However, SARS-CoV-2 PCR testing capacity has been limited and the incidence of COVID-19 infections is unknown. Volunteer healthy blood donors can be a control
Externí odkaz:
https://doaj.org/article/ca824906032d4a5d88a8db4beed08a47
Autor:
Syed Hani Abidi, Kehkashan Imtiaz, Akbar Kanji, Shama Qaiser, Erum Khan, Kiran Iqbal, Marc Veldhoen, Kulsoom Ghias, J Pedro Simas, Zahra Hasan
Publikováno v:
PLoS ONE, Vol 16, Iss 12, p e0259551 (2021)
BackgroundIndividuals recovering from COVID-19 are known to have antibodies against the Spike and other structural proteins. Antibodies against Spike have been shown to display viral neutralization. However, not all antibodies against Spike have neut
Externí odkaz:
https://doaj.org/article/f3b9265d120346638c8dc864a392a169
Autor:
Bing Liu, Ángel L Álvarez, Qiming Sun, J. Pedro Simas, Min Tan, Franceline Juillard, Rute Chitas, Han Xue, Agnieszka Szymula, Colin E. McVey, Shijun Li, Tânia F Custódio, Kenneth M. Kaye, Jing Huang, She Chen
Publikováno v:
Nucleic Acids Research
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
'Nucleic Acids Research ', vol: 49, pages: 12895-12911 (2021)
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
'Nucleic Acids Research ', vol: 49, pages: 12895-12911 (2021)
Mixed lineage leukemia 1 (MLL1) is a histone methyltransferase. Kaposi's sarcoma-associated herpesvirus (KSHV) is a leading cause of malignancy in AIDS. KSHV latently infects tumor cells and its genome is decorated with epigenetic marks. Here, we sho
Autor:
Zahra Hasan, Kiran Iqbal Masood, Shama Qaiser, Erum Khan, Areeba Hussain, Zara Ghous, Unab Khan, Maliha Yameen, Imran Hassan, Muhammad Imran Nasir, Muhammad Farrukh Qazi, Haris Ali Memon, Shiza Ali, Sadaf Baloch, Zulfiqar A. Bhutta, Marc Veldhoen, J. Pedro Simas, Syed Faisal Mahmood, Rabia Hussain, Kulsoom Ghias
Long-term solutions against SARS-CoV-2 infections require understanding of immune protection induced by different vaccine COVID-19 formulations. We investigated humoral and cellular immunity induced by Sinopharm (BBIBP-CorV) in a region of high SARS-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::16aa2cf82cf9d8b68a9e6f9cc95cbbce
https://doi.org/10.1101/2022.11.30.518633
https://doi.org/10.1101/2022.11.30.518633
Autor:
Aline C Habison, Marta Pires de Miranda, Chantal Beauchemin, Min Tan, Sofia A Cerqueira, Bruno Correia, Rajesh Ponnusamy, Edward J Usherwood, Colin E McVey, J Pedro Simas, Kenneth M Kaye
Publikováno v:
PLoS Pathogens, Vol 13, Iss 9, p e1006555 (2017)
Many pathogens, including Kaposi's sarcoma herpesvirus (KSHV), lack tractable small animal models. KSHV persists as a multi-copy, nuclear episome in latently infected cells. KSHV latency-associated nuclear antigen (kLANA) binds viral terminal repeat
Externí odkaz:
https://doaj.org/article/7c5642703ce84bb681186f9a7a5ad271