Zobrazeno 1 - 10
of 10
pro vyhledávání: '"J. Paul Simon"'
Publikováno v:
BIOS. 80:164-169
The fruit from milk thistle (Silybum marianum) contains flavonolignans that posses therapeutic properties. Milk thistle extract is sold and taken as an herbal supplement. However, it is not regulated by the Food and Drug Administration. The amount of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1525e42fdb0ab28aedce70a92e659f1d
https://doi.org/10.1893/011.080.0404
https://doi.org/10.1893/011.080.0404
Autor:
Ivana Slamova, Rozita Adib, Stephan Ellmerich, Michal R. Golos, Janet A. Gilbertson, Nicola Botcher, Diana Canetti, Graham W. Taylor, Nigel Rendell, Glenys A. Tennent, Guglielmo Verona, Riccardo Porcari, P. Patrizia Mangione, Julian D. Gillmore, Mark B. Pepys, Vittorio Bellotti, Philip N. Hawkins, Raya Al-Shawi, J. Paul Simons
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
ATTR amyloidosis causes heart failure through the accumulation of misfolded transthyretin in cardiac muscle. Here the authors report a mouse model of ATTR amyloidosis and demonstrate the involvement of protease activity in ATTR amyloid deposition.
Externí odkaz:
https://doaj.org/article/52dd9743e5e94eff8fed79314e07bdac
Autor:
J. Paul Simon, Karl-Erik Eriksson
Publikováno v:
Holzforschung. 52:287-296
In this report, MM3 is validated for preliminary conformational screening of guaiacyl β-O-4 structures. Using the repeating unit of a guaiacyl β-O-4 oligomer, 2-(2-methoxyphenox),1,3-propanediol. the results of MM 3 and ab initio (HF/6-31G * ) opti
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::99476bbdc7d13dace64d53e091944e10
https://doi.org/10.1515/hfsg.1998.52.3.287
https://doi.org/10.1515/hfsg.1998.52.3.287
Autor:
J. Paul Simon, Karl-Erik Eriksson
Publikováno v:
hfsg. 49:429-438
This is the first in a series of papers reporting the results of molecular mechanics (MM3) calculations on β-O-4 linked dimeric and oligomeric lignin model compounds. In this initial communication, we present the most energetically preferred conform
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e172a58213994de70dbbe938d852e58e
https://doi.org/10.1515/hfsg.1995.49.5.429
https://doi.org/10.1515/hfsg.1995.49.5.429
Publikováno v:
Journal of Biological Chemistry. 249:1993-1999
An analysis of the subunit structure of l-threonine dehydratase (l-threonine hydro-lyase (deaminating)) from Clostridium tetanomorphum has revealed that the native enzyme, with a molecular weight of 184,000, is composed of four apparently identical s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::141aa26dfc1a88b0309d668d4133f5d5
https://doi.org/10.1016/s0021-9258(19)42785-3
https://doi.org/10.1016/s0021-9258(19)42785-3
Autor:
Raya Al-Shawi, Glenys A. Tennent, David J. Millar, Angela Richard-Londt, Sebastian Brandner, David J. Werring, J. Paul Simons, Mark B. Pepys
Publikováno v:
Open Biology, Vol 6, Iss 2 (2016)
Human amyloid deposits always contain the normal plasma protein serum amyloid P component (SAP), owing to its avid but reversible binding to all amyloid fibrils, including the amyloid β (Aβ) fibrils in the cerebral parenchyma plaques and cerebrovas
Externí odkaz:
https://doaj.org/article/f396179e10544602bce8dcc7789466b1
Publikováno v:
Cardiology Research and Practice, Vol 2012 (2012)
Cardiovascular disease is the leading worldwide cause of death. Apolipoprotein E (ApoE) is a 34-kDa circulating glycoprotein, secreted by the liver and macrophages with pleiotropic antiatherogenic functions and hence a candidate to treat hypercholest
Externí odkaz:
https://doaj.org/article/11323930837b4986b3e3ca5bdac8b27d
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