Výsledky vyhledávání - "J. Paul Elliott"

Akademický článek

Therapeutic time window for conivaptan treatment against stroke-evoked brain edema and blood-brain barrier disruption in mice.

Autor: Emil Zeynalov, Susan M Jones, J Paul Elliott

Publikováno v: PLoS ONE, Vol 12, Iss 8, p e0183985 (2017)

Ischemic stroke is often complicated by brain edema, disruption of blood-brain barrier (BBB), and uncontrolled release of arginine-vasopressin (AVP). Conivaptan, a V1a and V2 receptor antagonist, reduces brain edema and minimizes damage to the blood-

Externí odkaz: https://doaj.org/article/6f65f55b3dc84cc7ac39698ec7b3a997

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Akademický článek

Arginine-Vasopressin Receptor Blocker Conivaptan Reduces Brain Edema and Blood-Brain Barrier Disruption after Experimental Stroke in Mice.

Autor: Emil Zeynalov, Susan M Jones, Jeong-Woo Seo, Lawrence D Snell, J Paul Elliott

Publikováno v: PLoS ONE, Vol 10, Iss 8, p e0136121 (2015)

Stroke is a major cause of morbidity and mortality. Stroke is complicated by brain edema and blood-brain barrier (BBB) disruption, and is often accompanied by increased release of arginine-vasopressin (AVP). AVP acts through V1a and V2 receptors to t

Externí odkaz: https://doaj.org/article/933759a15f7a4dedb9d76231f78c714c

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Vasopressin and vasopressin receptors in brain edema

Autor: J Paul Elliott, Emil Zeynalov, Susan M. Jones

Vasopressin is a peptide hormone produced in the hypothalamus and released from the posterior pituitary. Secretion of vasopressin is followed by activation of its receptors V1a, V1b, and V2 throughout the body. Each receptor type is responsible for a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19fad4b55f88dbb03d550524078fa568
https://doi.org/10.1016/bs.vh.2019.08.015

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The Incidence and Impact of Secondary Cerebral Insults on Outcome After Aneurysmal Subarachnoid Hemorrhage

Autor: Peter D. Le Roux, Monisha A. Kumar, Sean Doerfler, Jennifer Faerber, Joshua M. Levine, Guy M. McKhann, H. Richard Winn, J. Paul Elliott

Publikováno v: World neurosurgery. 114

Secondary cerebral insults can adversely affect patients with traumatic brain injury. By contrast, the incidence of secondary cerebral insults after aneurysmal subarachnoid hemorrhage (SAH) and their impact on outcome have been less well studied.Four

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e2c60381c149dab31db7e56c07279586
https://pubmed.ncbi.nlm.nih.gov/29574224

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The Effects of Red Blood Cell Transfusion on Functional Outcome after Aneurysmal Subarachnoid Hemorrhage

Autor: Monisha A. Kumar, Peter D. Le Roux, Jennifer Faerber, J. Paul Elliott, Joshua M. Levine, Sean Doerfler, H. Richard Winn

Publikováno v: World neurosurgery. 108

Background The optimal red blood cell transfusion (RBCT) trigger for patients with aneurysmal subarachnoid hemorrhage (SAH) is unknown. In patients with cerebral vasospasm, anemia may increase susceptibility to ischemic injury; conversely, RBCT may w

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::95eca5f52357b265c0e9a9c337179983
https://pubmed.ncbi.nlm.nih.gov/29038077

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Continuous IV Infusion is the Choice Treatment Route for Arginine-vasopressin Receptor Blocker Conivaptan in Mice to Study Stroke-evoked Brain Edema

Autor: Emil Zeynalov, Susan M. Jones, J Paul Elliott

Stroke is one of the major causes of morbidity and mortality in the world. Stroke is complicated by brain edema and other pathophysiological events. Among the most important players in the development and evolution of stroke-evoked brain edema is the

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35a0eb936de6b7a5cf95d047d51e8a9c
https://europepmc.org/articles/PMC5091976/

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Association of a younger age with an increased risk of angiographic and symptomatic vasospasms following subarachnoid hemorrhage

Autor: J. Paul Elliott, Liyi Cen, H. Richard Winn, Rohan Ramakrishna, Peter D. Le Roux, H. Isaac Chen, Suresh N. Magge, Zhen Chen

Publikováno v: Journal of Neurosurgery. 112:1208-1215

Object Vasospasm is a leading cause of morbidity and death following aneurysmal subarachnoid hemorrhage (SAH). It is important to predict which patients are at risk for vasospasm so that interventions can be made. There are several potential risk fac

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c5dca56dad96cef42fc6886b6e679819
https://doi.org/10.3171/2009.9.jns081670

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Differential Cerebral Protein Synthesis and Heat Shock Protein 70 Expression in the Core and Penumbra of Rat Brain after Transient Focal Ischemia

Autor: Takamasa Kayama, Philip Weinstein, Warren R. Selman, Frank R. Sharp, J. Paul Elliott, Yasuaki Kokubo, Jialing Liu, R. Loch Macdonald, Sunita Rajdev

Publikováno v: Neurosurgery. 53:186-191

OBJECTIVE The purpose of this study was to correlate the cerebral protein synthesis (CPS) reductions in the ischemic core and penumbra with the metabolic stress response indicated by heat shock protein 70 (HSP70) synthesis. METHODS Rats were subjecte

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9d348d29da086b1100c784a83244ad56
https://doi.org/10.1227/01.neu.0000069023.01440.d6

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Bilateral Multiple Cervical Root Avulsions without Skeletal or Ligamentous Damage Resulting from Blast Injury: Case Report

Autor: John David Morenski, Anthony M. Avellino, J. Paul Elliott, H. Richard Winn

Publikováno v: Neurosurgery. 50:1368-1371

OBJECTIVE AND IMPORTANCEWe describe a unique case of multiple bilateral cervical root injuries without ligamentous or bony injury secondary to a sandblast accident.CLINICAL PRESENTATIONA 19-year-old man sustained a sandblast injury to his face, neck,

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2b2b258c3f0375019540164063d3ad79
https://doi.org/10.1097/00006123-200206000-00032

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Blood Transfusion during Aneurysm Surgery

Autor: H. Richard Winn, J. Paul Elliott, Peter D. Le Roux

Publikováno v: Neurosurgery. 49:1068-1075

INTRODUCTION Increasing costs and concerns about blood supply safety have led to a reevaluation of blood transfusion practices. This study was undertaken to examine blood use during aneurysm surgery. METHODS We performed a retrospective analysis of h

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76671bd23ae6ccf55eb68c90e3d4634c
https://doi.org/10.1227/00006123-200111000-00009

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