Zobrazeno 1 - 10
of 35
pro vyhledávání: '"J. Patrick Kesslak"'
Autor:
Susan Abushakra, Anton P. Porsteinsson, Marwan Sabbagh, David Watson, Aidan Power, Earvin Liang, Emer MacSweeney, Merce Boada, Susan Flint, Rosalind McLaine, J. Patrick Kesslak, John A. Hey, Martin Tolar
Publikováno v:
Alzheimer’s & Dementia: Translational Research & Clinical Interventions, Vol 10, Iss 3, Pp n/a-n/a (2024)
Abstract INTRODUCTION The approved amyloid antibodies for early Alzheimer's disease (AD) carry a boxed warning about the risk of amyloid‐related imaging abnormalities (ARIAs) that are highest in apolipoprotein E (APOE) ε4/ε4 homozygotes. ALZ‐80
Externí odkaz:
https://doaj.org/article/1448089f820249ebae05bff99a32e39a
Autor:
Alejandro R. Jadad, Veeraindar Goli, Scott R. Evans, Jeffrey Tobias, Dmitri Lissin, Vibeke Strand, Hilary D. Wilson, Michael P. McDermott, Kushang V. Patel, Nathaniel P. Katz, Jasvinder A. Singh, Penney Cowan, Michael C. Rowbotham, Roy Freeman, Roderick Junor, Cristina Sampaio, John T. Farrar, Ilona Steigerwald, J Patrick Kesslak, Robert H. Dworkin, Bethea A. Kleykamp, John D. Markman, Louis P. Garrison, Zubin Bhagwagar, Alec B. O'Connor, Susan S. Ellenberg, Philip J. Mease, Ernest A. Kopecky, Christopher Eccleston, Leslie Tive, Mark P. Jensen, Jennifer S. Gewandter, Smriti Iyengar, Srinivasa N. Raja, Dennis C. Turk, Ajay D. Wasan
Publikováno v:
Pain
Chronic pain clinical trials have historically assessed benefit and risk outcomes separately. However, a growing body of research suggests that a composite metric that accounts for benefit and risk in relation to each other can provide valuable insig
Autor:
Mark P. Jensen, Alejandro R. Jadad, John D. Markman, Christopher Eccleston, Leslie Tive, Roderick Junor, Hilary Wilson, Cornelia Kamp, Cristina Sampaio, Alec B. O'Connor, Nathaniel P. Katz, Shannon M. Smith, Penney Cowan, Robert H. Dworkin, Dennis C. Turk, Ajay D. Wasan, Ernest A. Kopecky, Susan S. Ellenberg, Smriti Iyengar, Philip J. Mease, John T. Farrar, Laurie B. Burke, Roy Freeman, Srinivasa N. Raja, Zubin Bhangwagar, David A. Schoenfeld, Scott R. Evans, Kushang V. Patel, Dmitri Lissin, Vibeke Strand, Ilona Steigerwald, Jasvinder A. Singh, J Patrick Kesslak, Louis P. Garrison, Michael P. McDermott, Michael C. Rowbotham, Jeffrey Tobias
Publikováno v:
Smith, S M, Dworkin, R H, Turk, D C, McDermott, M, Eccleston, C, Farrar, J T, Rowbotham, M C, Bhangwagar, Z, Burke, L, Cowan, P, Ellenberg, S S, Evans, S R, Freeman, R L, Garrison, L P, Iyengar, S, Jadad, A, Jensen, M P, Junor, R, Kamp, C, Katz, N P, Kesslak, J P, Kopecky, E A, Lissin, D, Markman, J D, Mease, P J, O'Connor, A B, Patel, K V, Raja, S N, Sampaio, C, Schoenfeld, D, Singh, J, Steigerwald, I, Strand, V, Tive, L A, Tobias, J, Wasan, A D & Wilson, H D 2020, ' Interpretation of chronic pain clinical trial outcomes: IMMPACT recommended considerations ', Pain, vol. 161, no. 11, pp. 2446-2461 . https://doi.org/10.1097/j.pain.0000000000001952
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Pain
Repositório Científico de Acesso Aberto de Portugal
Repositório Científico de Acesso Aberto de Portugal (RCAAP)
instacron:RCAAP
Pain
Copyright © 2020 International Association for the Study of Pain.
Interpreting randomized clinical trials (RCTs) is crucial to making decisions regarding the use of analgesic treatments in clinical practice. In this article, we report on an Ini
Interpreting randomized clinical trials (RCTs) is crucial to making decisions regarding the use of analgesic treatments in clinical practice. In this article, we report on an Ini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fd090b59bce8413f60de748da3d972de
https://purehost.bath.ac.uk/ws/files/205634866/PAIN_D_19_01166_R2_text_tables_figures.pdf
https://purehost.bath.ac.uk/ws/files/205634866/PAIN_D_19_01166_R2_text_tables_figures.pdf
Publikováno v:
The Journal of Spinal Cord Medicine. 30:263-271
The excitatory amino acid transporters (EAATs), or sodium-dependent glutamate transporters, provide the primary mechanism for glutamate removal from the synaptic cleft. EAAT distribution has been determined in the rat brain, but it is only partially
Publikováno v:
Neuroscience Letters. 353:95-98
Brain-derived neurotrophic factor (BDNF) is involved in activity-dependent plasticity and interacts with the neurotransmitter glutamate. Glutamate N-methl-D-aspartate (NMDA) receptor activation increases BDNF expression, while BDNF facilitates NMDA a
Publikováno v:
European Neurological Review. 12:92
Over half of patients with Parkinson’s disease (PD) develop symptoms of psychosis during the course of their disease. Existing guidelines include recommendations for managing symptoms of psychosis in patients with PD. However, the extent to which s
Publikováno v:
European Neurological Review. 12:87
Parkinson’s disease psychosis (PDP) is a clinical condition that affects patients diagnosed with Parkinson’s disease (PD) and has a spectrum of neuropsychiatric symptoms distinct from the hallmark motor symptoms. Although prior studies have repor
Publikováno v:
European Journal of Neuroscience. 14:1992-2002
We investigated the possibility that estrogen and exercise interact in the hippocampus and regulate brain-derived neurotrophic factor (BDNF), a molecule increasingly recognized for its role in plasticity and neuron function. An important aspect of th
Publikováno v:
Moore, Stephanie; Sandman, Curt A; McGrady, Katie; & Patrick Kesslak, J. (2001). Memory training improves cognitive ability in patients with dementia. Neuropsychological Rehabilitation, 11(3-4), 245-261. doi: 10.1080/09602010042000222. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/9fh0f38k
Clinical symptoms of Alzheimer's disease (AD) include a variety of progressive cognitive deficits, particularly memory. Twenty-five patients with mild to moderate AD and their caregivers, who served as controls, participated in a 5 week memory traini
Autor:
Andrea J. Tenner, Malcolm B. Dick, Carl W. Cotman, Matthew D. Smyth, David H. Cribbs, J. Patrick Kesslak, W.Rodman Shankle
Publikováno v:
Neurobiology of Aging. 15:609-614
Recent reports that complement proteins comprising the classical pathway are associated with senile plaques suggest that activation of the classical complement cascade in Alzheimer's disease tissue results in bystander cell lysis and may contribute t