Zobrazeno 1 - 10
of 162
pro vyhledávání: '"J. Parrick"'
Publikováno v:
Anti-Cancer Drugs. 10:777-784
Four novel 4-substituted 5-nitrophthalimides (5-substituted-6-nitro-1,3-dihydro-isoindol-1,3-diones), 6, 7, 10 and 11, and the known 5 are prepared as analogs of the dinitrobenzamide prodrug CB 1954, 1, and considered as potential candidates for gene
Autor:
J. PARRICK
Publikováno v:
ChemInform. 22
Publikováno v:
International Journal of Radiation Biology. 61:797-803
A novel 2-nitroimidazole with a theophylline side-chain, 7-(4'-(2-nitroimidazol-1-yl)-butyl)-theophylline, (NITP) was as efficient a hypoxic-cell radiosensitizer as misonidazole. However, if cells were irradiated with NITP under hypoxic conditions an
Autor:
J. Parrick, L.K. Mehta
This chapter is the review of developments in the physical properties, synthesis, and applications of fused bicyclic, tricyclic, and polycyclic azetes, azetines, and azetidines in the last decade. A noticeable feature is the increased number of fused
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb05818667f7006082b08ba1d4d72c65
https://doi.org/10.1016/b978-008044992-0.00204-2
https://doi.org/10.1016/b978-008044992-0.00204-2
Autor:
L. K. Mehta, J. Parrick
Publikováno v:
ChemInform. 34
Autor:
J. Parrick, L.K. Mehta
Publisher Summary The Four-membered heterocycles shows the continued development of azetidine chemistry, in part, because of the recognition of the ease of formation of l-azabicyclo butane and its conversion to azetidines. The volume of β-1actone ch
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c775be54164dac6d36eb9c167784ea3c
https://doi.org/10.1016/s0959-6380(96)80006-7
https://doi.org/10.1016/s0959-6380(96)80006-7
Publikováno v:
Anti-cancer drug design. 10(3)
NITP (1) is an effective marker of hypoxia in tumours for both microscopy and cell sorting studies and, additionally, the compound shows post-irradiation sensitization, probably by inhibition of repair of radiation damage to DNA. However, NITP does n
Publikováno v:
Anti-cancer drug design. 9(6)
The DNA-binding properties of six candidate nitroarene-functionalized oligopeptides 8-13 (i.e. 5-nitrofuran, 2-nitroimidazole and 4-nitrobenzene derivatives) with potential hypoxia-selective activity, developed as analogues of the archetypal minor gr
Autor:
L.K. Mehta, J. Parrick
Publikováno v:
A critical review of the 2000 literature preceded by two chapters on current heterocyclic topics ISBN: 9780080440057
Progress in Heterocyclic Chemistry ISBN: 9780080438825
Progress in Heterocyclic Chemistry ISBN: 9780080438825
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68b86ba06856d0ce64ab3aa06060050f
https://doi.org/10.1016/b978-0-08-042074-5.50009-8
https://doi.org/10.1016/b978-0-08-042074-5.50009-8