Výsledky vyhledávání - "J. Parra-Ruiz"

Experimental study of the application of a new bone cement loaded with broad spectrum antibiotics for the treatment of bone infection

Autor: J. García-García, G. Azuara, J.L. San Roman, Francisco J. Parra-Ruiz, Miguel A Ortega, B. G. De La Torre, Julia Buján, Blanca Vázquez-Lasa, Ángel Asúnsolo, B. Ibarra

Publikováno v: Revista Española de Cirugía Ortopédica y Traumatología (English Edition). 63:95-103

Objectives To evaluate the in vivo behaviour of a new bone cement loaded with antibiotics, in a rabbit bone infection model. Material and methods Sixteen New Zealand rabbits divided into 4 groups were used, depending on the cement (commercial or expe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::d19e8f120f029b6fcb9e49e9ab4d81bc
https://doi.org/10.1016/j.recote.2018.10.005

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Estudio experimental de la aplicación de un nuevo cemento óseo cargado con antibióticos de amplio espectro para el tratamiento de la infección ósea

Autor: B. Ibarra, Francisco J. Parra-Ruiz, Miguel A Ortega, B. G. De La Torre, Ángel Asúnsolo, Blanca Vázquez-Lasa, Julia Buján, J. García-García, G. Azuara, J.L. San Roman

Publikováno v: Revista Española de Cirugía Ortopédica y Traumatología. 63:95-103

Resumen Objetivos Valorar el comportamiento histologico, en un modelo animal de conejo, de un nuevo cemento oseo modificado, el cual aumenta la liberacion local de antibiotico, en la infeccion osea. Material y metodos Se han utilizado 16 conejos Nuev

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::04c2dcbdba12f90c0dd7399c77832fb6
https://doi.org/10.1016/j.recot.2018.10.002

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Enhanced Bioactivity of α-Tocopheryl Succinate Based Block Copolymer Nanoparticles by Reduced Hydrophobicity

Autor: Richard Hoogenboom, Susan N. Thomas, Samarendra Maji, Francisco J. Parra-Ruiz, Julio San Román, Raquel Palao-Suay, Nathan A. Rohner, María Rosa Aguilar

Publikováno v: Macromolecular Bioscience. 16:1824-1837

Well-structured amphiphilic copolymers are necessary to obtain self-assembled nanoparticles (NPs) based on synthetic polymers. Highly homogeneous and monodispersed macromolecules obtained by controlled polymerization have successfully been used for t

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ae89284ce372ac799f74c5e5922fef0
https://doi.org/10.1002/mabi.201600259

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Thermal Crosslinking of Maltodextrin and Citric Acid. Methodology to Control the Polycondensation Reaction under Processing Conditions

Autor: Francisco J. Parra-Ruiz, J.L. San Roman, M. Castro-Cabado, A.L. Casado

Publikováno v: Scopus-Elsevier

This paper presents an affordable methodology for the analysis of the crosslinking, by polycondensation reaction, between maltodextrin and citric acid under thermal processing. This methodology is based on three complementary analytical techniques: F

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94b8d7eefb7e08cfa76569ba1faceafc
https://doi.org/10.1177/096739111602400803

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α-TOS-based RAFT block copolymers and their NPs for the treatment of cancer

Autor: María Rosa Aguilar, Richard Hoogenboom, Raquel Palao-Suay, Nathan A. Rohner, Samarendra Maji, Susan N. Thomas, Julio San Román, Francisco J. Parra-Ruiz

Publikováno v: Digital.CSIC. Repositorio Institucional del CSIC
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α-Tocopheryl succinate (α-TOS) is a well-known mitochondrially targeted anticancer compound. However, a major factor limiting the use of α-TOS is its low solubility in physiological media. To overcome this problem, the aim of this work is the prep

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::010c1bdd131087b64665b25f4b1bfa89
https://doi.org/10.1039/c5py01811k

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Experimental study of the application of a new bone cement loaded with broad spectrum antibiotics for the treatment of bone infection

Autor: G, Azuara, J, García-García, B, Ibarra, F J, Parra-Ruiz, A, Asúnsolo, M A, Ortega, B, Vázquez-Lasa, J, Buján, J, San Román, B, de la Torre

Publikováno v: Revista espanola de cirugia ortopedica y traumatologia (English ed.). 63(2)

To evaluate the in vivo behaviour of a new bone cement loaded with antibiotics, in a rabbit bone infection model.Sixteen New Zealand rabbits divided into 4 groups were used, depending on the cement (commercial or experimental) and the antibiotic (van

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6a6da9cef1f42752649e18d4f2832e31
https://pubmed.ncbi.nlm.nih.gov/30611707

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Concomitant tuberculosis and lung cancer diagnosed by bronchoscopy

Autor: C Morales-García, A E Delgado-Martín, J Hernández-Quero, J Parra-Ruiz, J A Sánchez-Martínez, A Amzouz-Amzouz

Publikováno v: The International Journal of Tuberculosis and Lung Disease. 19:1027-1032

Setting South Granada Health Area (SGHA), Spain. Objective To describe the characteristics of concomitant tuberculosis (TB) and lung cancer cases. Design A total of 319 TB cases diagnosed between January 2003 and December 2010 were evaluated and iden

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8a5e83eb78413fe3c5c92ca44e6591c6
https://doi.org/10.5588/ijtld.14.0578

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Multifunctional decoration of alpha-tocopheryl succinate-based NP for cancer treatment: effect of TPP and LTVSPWY peptide

Autor: Raquel Palao-Suay, Francisco J. Parra-Ruiz, Susan N. Thomas, Sergio Martín-Saldaña, María Rosa Aguilar, Julio San Román, Nathan A. Rohner

Publikováno v: Journal of Materials Science: Materials in Medicine. 28

Active targeting not only of a specific cell but also a specific organelle maximizes the therapeutic activity minimizing adverse side effects in healthy tissues. The present work describes the synthesis, characterization, and in vitro biological acti

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6150b809536a12aa02c0a78d4aa141cc
https://doi.org/10.1007/s10856-017-5963-y

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Photothermal and photodynamic activity of polymeric nanoparticles based on α-tocopheryl succinate-RAFT block copolymers conjugated to IR-780

Autor: Francisco Martín-Saavedra, Francisco J. Parra-Ruiz, Nathan A. Rohner, Julio San Román, Raquel Palao-Suay, Clara Escudero-Duch, Susan N. Thomas, María Rosa Aguilar, Sergio Martín-Saldaña, Nuria Vilaboa

Publikováno v: Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid

The aim of this work was the generation of a multifunctional nanopolymeric system that incorporates IR-780 dye, a near-infrared (NIR) imaging probe that exhibits photothermal and photodynamic properties; and a derivate of α-tocopheryl succinate (α-

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fbd31a4eab18b9723f1f0fbca130c5b9
https://hdl.handle.net/20.500.12530/39595

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