Zobrazeno 1 - 10
of 54
pro vyhledávání: '"J. P. Tam"'
Publikováno v:
Biopolymers. 60(3)
This review focuses on the concept, methods, and strategies of orthogonal peptide ligation. It updates our previous review in 1999 on the same subject matter in Biopolymers (Peptide Science, 1999, Vol. 51, p. 311). Orthogonal peptide ligation is an a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7e4cd849b556de67eedf80a5a28e9782
https://pubmed.ncbi.nlm.nih.gov/11774225
https://pubmed.ncbi.nlm.nih.gov/11774225
Publikováno v:
European journal of biochemistry. 267(11)
To correlate conformational rigidity with membranolytic selectivity of antimicrobial activity and cytotoxicity, we prepared six cyclic analogs of protegrin-1 (PG-1), an 18-residue cationic peptide with a broad-spectrum antimicrobial activity. These c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1528e3176abacb16507c7e9617d08ae0
https://pubmed.ncbi.nlm.nih.gov/10824115
https://pubmed.ncbi.nlm.nih.gov/10824115
Publikováno v:
The Journal of biological chemistry. 275(10)
To determine the intracellular signaling mechanism of the 5-HT(2C) receptor endogenously expressed in choroid plexus epithelial cells, we implemented a strategy of targeted disruption of protein-protein interactions. This strategy entails the deliver
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f080673fbb0457a04b8ab9910da4512f
https://pubmed.ncbi.nlm.nih.gov/10702266
https://pubmed.ncbi.nlm.nih.gov/10702266
Autor:
J P, Tam
Publikováno v:
Biopolymers. 51(5)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fde6a2463f9c1d839a6b2551f48918dd
https://pubmed.ncbi.nlm.nih.gov/10685042
https://pubmed.ncbi.nlm.nih.gov/10685042
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 161(7)
To generate a useful strategy for mucosal immunization, we have developed an approach of lipidating a multiple Ag peptide (MAP) containing part of the V3 loop from HIV-1 gp120IIIB. In this work, we compare two delivery systems, lipidated MAP in PBS a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::44b699a9cb3dd0f48442594c774a1e09
https://pubmed.ncbi.nlm.nih.gov/9759884
https://pubmed.ncbi.nlm.nih.gov/9759884
Publikováno v:
Biopolymers. 46(5)
In biological systems, both proteolysis and aminolysis of amide bonds produce activated intermediates through acyl transfer reactions either inter- or intramolecularly. Protein splicing is an illustrative example that proceeds through a series of cat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::738e4ec914679f4e1f73c8b0f376792a
https://pubmed.ncbi.nlm.nih.gov/9754028
https://pubmed.ncbi.nlm.nih.gov/9754028
Publikováno v:
Developments in biological standardization. 92
We describe the design and development of a novel peptide-based approach for mucosal immunization. The design contains an amplified peptide chain as multiple antigen peptide (MAP) with a cluster of lipids. Such a design would confer on lipidated MAP
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::379bf281e48a3d77bf81f9ca2a23784c
https://pubmed.ncbi.nlm.nih.gov/9554263
https://pubmed.ncbi.nlm.nih.gov/9554263
Autor:
J P, Tam, J C, Spetzler
Publikováno v:
Methods in enzymology. 289
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::eb740fbff31c979a7f2ebebe0195c134
https://pubmed.ncbi.nlm.nih.gov/9353741
https://pubmed.ncbi.nlm.nih.gov/9353741
Autor:
J C, Spetzler, J P, Tam
Publikováno v:
Peptide research. 9(6)
Multiple cyclic antigen peptides (McAPs) are dendrimers that have branched, multiple closed-chain architectures. We describe an approach for their stepwise, solid-phase synthesis that permits a self-assembly of cyclization reactions of a McAP with fo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0aa88402b1e61d1b60cf4a0afe38a79f
https://pubmed.ncbi.nlm.nih.gov/9048422
https://pubmed.ncbi.nlm.nih.gov/9048422
Publikováno v:
Peptide research. 8(3)
A systematic approach to map the functionally important determinants of endothelin-1 (ET-1) by a D-amino acid scan is described. Correct orientation of the amino acid side chains was generally of paramount importance both for binding at the ETA recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::fd8c2f5d96b0ebd4127925dc06b68ad6
https://pubmed.ncbi.nlm.nih.gov/7670230
https://pubmed.ncbi.nlm.nih.gov/7670230