The scientific rationale and study protocol for the DPP3, Angiotensin II, and Renin Kinetics in Sepsis (DARK-Sepsis) randomized controlled trial: serum biomarkers to predict response to angiotensin II versus standard-of-care vasopressor therapy in the treatment of septic shock

Autor: J. Pedro Teixeira, David Perez Ingles, Jordan B. Barton, James T. Dean, Pablo Garcia, Susan J. Kunkel, Preeyaporn Sarangarm, Natalie K. Weiss, Christopher L. Schaich, Laurence W. Busse, Nathan D. Nielsen

Publikováno v: Trials, Vol 25, Iss 1, Pp 1-12 (2024)

Abstract Background Data to support the use of specific vasopressors in septic shock are limited. Since angiotensin II (AT2) was approved by the Food and Drug Administration in 2017, multiple mechanistically distinct vasopressors are available to tre

Externí odkaz: https://doaj.org/article/44cb25ba93fc446daac181d7c3c7cf82

Angiotensin ii therapy in refractory septic shock: which patient can benefit most? A narrative review

Autor: Irene Coloretti, Andrea Genovese, J. Pedro Teixeira, Anusha Cherian, Ricard Ferrer, Giovanni Landoni, Marc Leone, Massimo Girardis, Nathan D. Nielsen

Publikováno v: Journal of Anesthesia, Analgesia and Critical Care, Vol 4, Iss 1, Pp 1-9 (2024)

Abstract Patients with septic shock who experience refractory hypotension despite adequate fluid resuscitation and high-dose noradrenaline have high mortality rates. To improve outcomes, evidence-based guidelines recommend starting a second vasopress

Externí odkaz: https://doaj.org/article/ead94547494748ffa7338ca90b361cb6

Correction: Allied health professionals’ experiences and views towards improving musculoskeletal services in the UK for patients with musculoskeletal and co-existing mental health conditions: a qualitative study

Autor: Rokhsaneh Tehrany, Dana Maki, Maria J C Teixeira, Tanya Chumak, Christine Hoerz

Publikováno v: BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-1 (2024)

Externí odkaz: https://doaj.org/article/3bf133108acd40e6817c5438563379d4

Early vigabatrin augmenting GABA-ergic pathways in post-anoxic status epilepticus (VIGAB-STAT) phase IIa clinical trial study protocol

Autor: Carolina B. Maciel, Fernanda J. P. Teixeira, Katie J. Dickinson, Jessica C. Spana, Lisa H. Merck, Alejandro A. Rabinstein, Robert Sergott, Guogen Shan, Guanhong Miao, Charles A. Peloquin, Katharina M. Busl, Lawrence J. Hirsch

Publikováno v: Neurological Research and Practice, Vol 4, Iss 1, Pp 1-9 (2022)

Abstract Background Nearly one in three unconscious cardiac arrest survivors experience post-anoxic status epilepticus (PASE). Historically, PASE has been deemed untreatable resulting in its exclusion from status epilepticus clinical trials. However,

Externí odkaz: https://doaj.org/article/7278cb4a13c74708827fae6bb045f1b5

Arbuscular mycorrhizal trees influence the latitudinal beta-diversity gradient of tree communities in forests worldwide

Autor: Yonglin Zhong, Chengjin Chu, Jonathan A. Myers, Gregory S. Gilbert, James A. Lutz, Jonas Stillhard, Kai Zhu, Jill Thompson, Jennifer L. Baltzer, Fangliang He, Joseph A. LaManna, Stuart J. Davies, Kristina J. Aderson-Teixeira, David F.R.P. Burslem, Alfonso Alonso, Kuo-Jung Chao, Xugao Wang, Lianming Gao, David A. Orwig, Xue Yin, Xinghua Sui, Zhiyao Su, Iveren Abiem, Pulchérie Bissiengou, Norm Bourg, Nathalie Butt, Min Cao, Chia-Hao Chang-Yang, Wei-Chun Chao, Hazel Chapman, Yu-Yun Chen, David A. Coomes, Susan Cordell, Alexandre A. de Oliveira, Hu Du, Suqin Fang, Christian P. Giardina, Zhanqing Hao, Andrew Hector, Stephen P. Hubbell, David Janík, Patrick A. Jansen, Mingxi Jiang, Guangze Jin, David Kenfack, Kamil Král, Andrew J. Larson, Buhang Li, Xiankun Li, Yide Li, Juyu Lian, Luxiang Lin, Feng Liu, Yankun Liu, Yu Liu, Fuchen Luan, Yahuang Luo, Keping Ma, Yadvinder Malhi, Sean M. McMahon, William McShea, Hervé Memiaghe, Xiangcheng Mi, Mike Morecroft, Vojtech Novotny, Michael J. O’Brien, Jan den Ouden, Geoffrey G. Parker, Xiujuan Qiao, Haibao Ren, Glen Reynolds, Pavel Samonil, Weiguo Sang, Guochun Shen, Zhiqiang Shen, Guo-Zhang Michael Song, I-Fang Sun, Hui Tang, Songyan Tian, Amanda L. Uowolo, María Uriarte, Bin Wang, Xihua Wang, Youshi Wang, George D. Weiblen, Zhihong Wu, Nianxun Xi, Wusheng Xiang, Han Xu, Kun Xu, Wanhui Ye, Mingjian Yu, Fuping Zeng, Minhua Zhang, Yingming Zhang, Li Zhu, Jess K. Zimmerman

Publikováno v: Nature Communications, Vol 12, Iss 1, Pp 1-12 (2021)

The relationship of mycorrhizal associations with latitudinal gradients in tree beta-diversity is unexplored. Using a global dataset approach, this study examines how trees with arbuscular mycorrhizal and ectomycorrhizal associations contribute to la

Externí odkaz: https://doaj.org/article/65abd7d03401492da58b7c902d21658d