Zobrazeno 1 - 10
of 85
pro vyhledávání: '"J. P. Seguela"'
Autor:
Marie-Hélène Bessières, Sophie Cassaing, C Courjault, C. Roques, Michel Rolland, Alain Berrebi, J. P. Seguela, M. C. Bloom
Publikováno v:
European Journal of Obstetrics & Gynecology and Reproductive Biology. 94:37-45
The aim of this study was to determine the performances of methods used for the neonatal diagnosis of congenital toxoplasmosis. We included 165 pregnant women infected during pregnancy over a 10-year period. Fifty-seven cases of congenital toxoplasmo
Autor:
Sophie Cassaing, Josette Fauvel, Marie-Hélène Bessières, Sandrine Guy, Hugues Chap, J. P. Seguela
Publikováno v:
International Journal for Parasitology. 30:1137-1142
Phospholipases A(2) (PLA(2)) play an important role in Toxoplasma gondii host cell penetration. They are also key enzymes in the host cell response to the parasite invasion. PLA(2) hydrolyse cellular phospholipids, releasing multiple inflammatory lip
Autor:
R. Caujolle, J. P. Seguela, C. Tournaire‐Arellano, M. D. Linas, J. L. Stigliani, C. Recoche, Marc Payard
Publikováno v:
European Journal of Medicinal Chemistry. 32:1001-1007
Summary Ethers of 1-(2,4-dichlorophenyl)-2-(1- H -imidazolyl)ethanol bearing ramified and/or unsaturated chains have been synthesized in order to specify the role of lipophilicity or steric contributions on antifungal activity against yeast for micon
Publikováno v:
Revue Française des Laboratoires. 1998:53-57
Resume Le depistage de l'infection congenitale s'impose chez les femmes enceintes atteintes de toxoplasmose durant la grossesse. Le diagnostic antenatal le permet grâce au prelevement de liquide amniotique avec recherche de Toxoplasma gondii dans ce
Publikováno v:
European Journal of Medicinal Chemistry. 30:955-962
Summary Aromatic ethers related to antifungal azole miconazole were synthesized and tested against various strains of Candida . We found that activity is related to the nature of the aromatic ring and the position of substituents on this ring. Activi
Autor:
Philippe Gayral, J. P. Seguela, Christian Bories, H Amarouch, Linas, R Caujolle, Marc Payard, Philippe M. Loiseau
Publikováno v:
European Journal of Medicinal Chemistry. 30:801-807
Twenty-three arylthioureines bearing β-alanine or γ-aminobutyric alkyl ester chains were synthesized for in vitro screening toward 44 strains of fungi and 2 genera of nematodes. The nitro derivatives were the most potent compounds against Aspergill
Publikováno v:
Antimicrobial Agents and Chemotherapy. 38:2857-2862
We developed a new in vitro method of evaluating antifungal molecules. Fungal growth was determined by measuring glucose consumption, the only carbon source in a synthetic medium. First, the growth of 12 Aspergillus fumigatus strains was studied. Glu
Publikováno v:
Microbiology and Immunology. 38:909-913
This study was carried out to evaluate the effect of excreted/secreted antigens on macrophages infected by Toxoplasma gondii. Six proteins 28, 30, 45, 58, 63 and 145 kDa were separated by different chromatographic techniques. Mouse peritoneal macroph
Publikováno v:
European Journal of Medicinal Chemistry. 29:701-706
Aliphatic ethers 2 and esters 3, which are closely related to antifungal azoles, were synthesized and tested against various strains of Candida. We found that their activity was strongly related to the length of the chains; the best activity was obta
Autor:
G Baziard-Mouysset, Christian Bories, Philippe R Loiseau, Philippe Gayral, Linas, R Caujolle, H Amarouch, J. P. Seguela, J. D. Favrot, Philippe M. Loiseau, M. Payard
Publikováno v:
European Journal of Medicinal Chemistry. 28:29-35
Twenty-seven arylalkyl- or arylvinylthiazolines were synthesized and tested in vitro against three genera of nematodes, various yeasts and opportunistic fungi. Vinyl compounds seem to have an interesting filaricidal activity against Molinema dessetae