Zobrazeno 1 - 10
of 82
pro vyhledávání: '"J. P. O'hare"'
Autor:
Petra Hanson, Christopher J. Philp, Harpal S. Randeva, Sean James, J. Paul O’Hare, Thomas Meersmann, Galina E. Pavlovskaya, Thomas M. Barber
Publikováno v:
JCI Insight, Vol 6, Iss 12 (2021)
BACKGROUND. Dietary sodium intake mismatches urinary sodium excretion over prolonged periods. Our aims were to localize and quantify electrostatically bound sodium within human skin using triple-quantum–filtered (TQF) protocols for MRI and magnetic
Externí odkaz:
https://doaj.org/article/d89ea2b453404ee9b0b046ce7f0ce199
Autor:
Rhona Johnston, Olalekan Uthman, Ewen Cummins, Christine Clar, Pamela Royle, Jill Colquitt, Bee Kang Tan, Andrew Clegg, Saran Shantikumar, Rachel Court, J Paul O’Hare, David McGrane, Tim Holt, Norman Waugh
Publikováno v:
Health Technology Assessment, Vol 21, Iss 2 (2018)
Externí odkaz:
https://doaj.org/article/b154ad873e2544258b9edb28ab68922a
Autor:
Rhona Johnston, Olalekan Uthman, Ewen Cummins, Christine Clar, Pamela Royle, Jill Colquitt, Bee Kang Tan, Andrew Clegg, Saran Shantikumar, Rachel Court, J Paul O’Hare, David McGrane, Tim Holt, Norman Waugh
Publikováno v:
Health Technology Assessment, Vol 21, Iss 2 (2017)
Background: Most people with type 2 diabetes are overweight, so initial treatment is aimed at reducing weight and increasing physical activity. Even modest weight loss can improve control of blood glucose. If drug treatment is necessary, the drug of
Externí odkaz:
https://doaj.org/article/1f9dc711b4bd44fc9bd1755140799fcb
Autor:
M Ann Kelly, Simon D Rees, M Zafar I Hydrie, A Samad Shera, Srikanth Bellary, J Paul O'Hare, Sudhesh Kumar, Shahrad Taheri, Abdul Basit, Anthony H Barnett, DIAGRAM Consortium, SAT2D Consortium
Publikováno v:
PLoS ONE, Vol 7, Iss 4, p e32670 (2012)
Disruption of endogenous circadian rhythms has been shown to increase the risk of developing type 2 diabetes, suggesting that circadian genes might play a role in determining disease susceptibility. We present the results of a pilot study investigati
Externí odkaz:
https://doaj.org/article/09e23ba8822b4ec5b81317635c37f156
Autor:
Simon D Rees, M Zafar I Hydrie, J Paul O'Hare, Sudhesh Kumar, A Samad Shera, Abdul Basit, Anthony H Barnett, M Ann Kelly
Publikováno v:
PLoS ONE, Vol 6, Iss 9, p e24710 (2011)
BACKGROUND: The Meta-Analysis of Glucose and Insulin related traits Consortium (MAGIC) recently identified 16 loci robustly associated with fasting glucose, some of which were also associated with type 2 diabetes. The purpose of our study was to expl
Externí odkaz:
https://doaj.org/article/2cfc25109adc466bb0e2d780e408bad6
Autor:
Dara Al-Disi, Milan K. Piya, Philip G. McTernan, John C. Clapham, Nasser M. Al-Daghri, J. P. O'Hare, Thomas M. Barber, Warunee Kumsaiyai, Alison L. Harte, Sudhesh Kumar, Gyanendra Tripathi, Ponnusamy Saravanan, Anne E. Fowler
Publikováno v:
Obesity. 21:2322-2330
OBJECTIVE: Central obesity and sub-clinical inflammation increase metabolic risk, this study examined the intracellular inflammatory pathways in adipose tissue (AT) that contribute to this risk. DESIGN AND METHODS: This study therefore addressed the
Publikováno v:
Integrated Diabetes Care ISBN: 9783319133881
The rapid increase in the prevalence of diabetes is not abating across the world. The cost burden of managing diabetes and its complications is putting significant strain on healthcare resources worldwide. Increasingly large proportions of patients w
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::13fea288a22d0e97b4a052f4c9314acc
https://doi.org/10.1007/978-3-319-13389-8_9
https://doi.org/10.1007/978-3-319-13389-8_9
Autor:
Barbara E. K. Klein, Mohan Rema, Miho Yasuda, Jie Jin Wang, Ecosse L. Lamoureux, Ronald Klein, Paul Mitchell, Tien Yin Wong, Hugh R. Taylor, Jakob Grauslund, James M. Tielsch, Toke Bek, M. Kamran Ikram, Astrid E. Fletcher, Sophie Rogers, Xinzhi Zhang, Tarun Sharma, Jonathan E. Shaw, Massimo Porta, Ningli Wang, Trevor J. Orchard, Korapat Mayurasakorn, Sannapaneni Krishnaiah, J. P. O'Hare, Liang Xu, Sheila K. West, Rohit Varma, Jacqueline M. Dekker, Richard F. Hamman, Steven M. Haffner, Ryo Kawasaki, Monique S. Roy, Joanne W.Y. Yau, Takamasa Kayama, Shih-Jen Chen, Jonathan W. Kowalski
Publikováno v:
Diabetes Care, 35(3), 556-564. American Diabetes Association
Diabetes Care, 35(3), 556-564. American Diabetes Association Inc.
Yau, J W Y, Rogers, S L, Kawasaki, R, Lamoureux, E L, Kowalski, J W, Bek, T, Chen, S-J, Dekker, J M, Fletcher, A, Grauslund, J, Haffner, S, Hamman, R F, Ikram, M K, Kayama, T, Klein, B E K, Klein, R, Krishnaiah, S, Mayurasakorn, K, O'Hare, J P, Orchard, T J, Porta, M, Rema, M, Roy, M S, Sharma, T, Shaw, J, Taylor, H, Tielsch, J M, Varma, R, Wang, J J, Wang, N, West, S, Xu, L, Yasuda, M, Zhang, X, Mitchell, P, Wong, T Y & Meta-Analysis for Eye Disease (META-EYE) Study Group 2012, ' Global prevalence and major risk factors of diabetic retinopathy ', Diabetes Care, vol. 35, no. 3, pp. 556-64 . https://doi.org/10.2337/dc11-1909
Diabetes Care
Yau, J W Y, Rogers, S L, Kawasaki, R, Lamoureux, E L, Kowalski, J W, Bek, T, Chen, S J, Dekker, J M, Fletcher, A, Grauslund, J, Haffner, S, Hamman, R F, Ikram, M K, Kayama, T, Klein, B E K, Klein, R, Krishnaiah, S, Mayurasakorn, K, O'Hare, J P, Orchard, T J, Porta, M, Rema, M, Roy, M S, Sharma, T, Shaw, J, Taylor, H, Tielsch, J M, Varma, R, Wang, J J, Wang, N L, West, S, Xu, L, Yasuda, M, Zhang, X Z, Mitchell, P & Wong, T Y 2012, ' Global Prevalence and Major Risk Factors of Diabetic Retinopathy ', Diabetes Care, vol. 35, no. 3, pp. 556-564 . https://doi.org/10.2337/dc11-1909
Diabetes Care, 35(3), 556-564. American Diabetes Association Inc.
Yau, J W Y, Rogers, S L, Kawasaki, R, Lamoureux, E L, Kowalski, J W, Bek, T, Chen, S-J, Dekker, J M, Fletcher, A, Grauslund, J, Haffner, S, Hamman, R F, Ikram, M K, Kayama, T, Klein, B E K, Klein, R, Krishnaiah, S, Mayurasakorn, K, O'Hare, J P, Orchard, T J, Porta, M, Rema, M, Roy, M S, Sharma, T, Shaw, J, Taylor, H, Tielsch, J M, Varma, R, Wang, J J, Wang, N, West, S, Xu, L, Yasuda, M, Zhang, X, Mitchell, P, Wong, T Y & Meta-Analysis for Eye Disease (META-EYE) Study Group 2012, ' Global prevalence and major risk factors of diabetic retinopathy ', Diabetes Care, vol. 35, no. 3, pp. 556-64 . https://doi.org/10.2337/dc11-1909
Diabetes Care
Yau, J W Y, Rogers, S L, Kawasaki, R, Lamoureux, E L, Kowalski, J W, Bek, T, Chen, S J, Dekker, J M, Fletcher, A, Grauslund, J, Haffner, S, Hamman, R F, Ikram, M K, Kayama, T, Klein, B E K, Klein, R, Krishnaiah, S, Mayurasakorn, K, O'Hare, J P, Orchard, T J, Porta, M, Rema, M, Roy, M S, Sharma, T, Shaw, J, Taylor, H, Tielsch, J M, Varma, R, Wang, J J, Wang, N L, West, S, Xu, L, Yasuda, M, Zhang, X Z, Mitchell, P & Wong, T Y 2012, ' Global Prevalence and Major Risk Factors of Diabetic Retinopathy ', Diabetes Care, vol. 35, no. 3, pp. 556-564 . https://doi.org/10.2337/dc11-1909
OBJECTIVE To examine the global prevalence and major risk factors for diabetic retinopathy (DR) and vision-threatening diabetic retinopathy (VTDR) among people with diabetes. RESEARCH DESIGN AND METHODS A pooled analysis using individual participant
Autor:
Shaun Sabico, K. C. McGee, Antonio Ceriello, Nasser M. Al-Daghri, Ponnusamy Saravanan, J. P. O'Hare, Philip G. McTernan, Sudhesh Kumar, Alison L. Harte, Gyanendra Tripathi, Omar S. Al-Attas, Madhusudhan C. Varma
Publikováno v:
Diabetes Care
OBJECTIVE To evaluate the changes in circulating endotoxin after a high–saturated fat meal to determine whether these effects depend on metabolic disease state. RESEARCH DESIGN AND METHODS Subjects (n = 54) were given a high-fat meal (75 g fat, 5 g
Autor:
Tazeen H. Jafar, Srikanth Bellary, Anthony H. Barnett, M. A. Kelly, Sudhesh Kumar, Dharambir K. Sanghera, A. S. Shera, M. Z. I. Hydrie, Simon D. Rees, Muhammad Islam, Timothy M. Frayling, J. P. O'Hare, Nish Chaturvedi, B. K. Chaudhary, Abdul Basit, Michael N. Weedon, Shiraz Hashmi
Publikováno v:
Diabetic Medicine. 28:673-680
Aims - A common variant, rs9939609, in the FTO (fat mass and obesity) gene is associated with adiposity in Europeans, explaining its relationship with diabetes. However, data are inconsistent in South Asians. Our aim was to investigate the associatio