Zobrazeno 1 - 2
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pro vyhledávání: '"J. P. Godbout"'
Autor:
L. D. Otto‐Dobos, J. C. Santos, L. D. Strehle, C. V. Grant, L. A. Simon, B. Oliver, J. P. Godbout, J. F. Sheridan, R. M. Barrientos, E. R. Glasper, L. M. Pyter
Publikováno v:
Journal of Neurochemistry.
Publikováno v:
Cellular signalling. 11(1)
Activation of the caspase proteases by c-Jun N-terminal kinase 1 (JNK1) has been proposed as a mechanism of apoptotic cell death. Here we report that insulin activates caspase-3 by a pathway requiring phosphatidylinositol 3'-kinase (PI3-kinase). JNK1