Zobrazeno 1 - 10
of 52
pro vyhledávání: '"J. P. Filkins"'
Publikováno v:
The International journal of artificial organs. 15(11)
Peritoneal dialysis was performed on 7 end-stage renal failure patients using an I-lactate-containing solution sterilized by ultrafiltration through polyamide filters. The patients tolerated the procedure well while their metabolic acidosis and azote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::9c6ab871dd7ae958c3216db839b220dd
https://pubmed.ncbi.nlm.nih.gov/1490757
https://pubmed.ncbi.nlm.nih.gov/1490757
Publikováno v:
Circulatory shock. 38(2)
Endotoxin induces insulin hypersecretion in vivo, which results in hyperinsulinemia and glucose dyshomeostasis. Polymyxin-B (PMX-B), an inhibitor of protein kinase C (PKC), has been shown to ameliorate the consequences of endotoxin-induced hyperinsul
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::aba80f4ac86ac2bd87c47d9f3bc80793
https://pubmed.ncbi.nlm.nih.gov/1423925
https://pubmed.ncbi.nlm.nih.gov/1423925
Autor:
H, Inaba, J P, Filkins
Publikováno v:
Circulatory shock. 34(4)
Intravenous glucose tolerance tests (IVGTTs) using 1.2 g/kg of D-glucose in fasted, male rats were repeated twice, with an interval of 75 min, during early (2.5 hr) and late (26.5 hr) nonlethal endotoxicosis induced by Salmonella enteritidis endotoxi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::3b2033423b3a68842a56f6daa77d5a6a
https://pubmed.ncbi.nlm.nih.gov/1773482
https://pubmed.ncbi.nlm.nih.gov/1773482
Autor:
A W, Yu, F J, Manahan, J P, Filkins, M S, Mohammed, R, Soundararajan, A P, McShane, V C, Gandhi, T S, Ing
Publikováno v:
The International journal of artificial organs. 14(8)
We performed acute peritoneal dialysis on eight end-stage renal disease patients using a bicarbonate-containing solution sterilized by ultrafiltration through polyamide filters. The patients tolerated the procedure well; their azotemia and metabolic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f8b8e4a52dfd9c20fdf7e81572313fe4
https://pubmed.ncbi.nlm.nih.gov/1937936
https://pubmed.ncbi.nlm.nih.gov/1937936
Autor:
H. Inaba, J. P. Filkins
Publikováno v:
The American journal of physiology. 261(1 Pt 2)
Activation of protein kinase C (PKC) by bacterial lipopolysaccharide had recently been implicated in the pathogenetic sequence of gram-negative sepsis, endotoxicosis, hyperinsulinism, and the alterations in glucoregulation that eventuate in glucose d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::300f31f85481f60acdd7ba60dac017e9
https://pubmed.ncbi.nlm.nih.gov/1858953
https://pubmed.ncbi.nlm.nih.gov/1858953
Autor:
H. Inaba, J. P. Filkins
Publikováno v:
The American journal of physiology. 260(3 Pt 2)
To investigate the role of protein kinase C (PKC) activation in the pathogenesis of endotoxin (ETX) shock, the in vivo effects of phorbol 12-myristate 13-acetate (PMA) on ETX-induced lethality and glucose dyshomeostasis were determined. Fed rats (300
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fb79f01a5177eee21bb18d13cfb647f8
https://pubmed.ncbi.nlm.nih.gov/2000998
https://pubmed.ncbi.nlm.nih.gov/2000998
Publikováno v:
Circulatory shock. 33(2)
A comparative and interactive analysis of the effects of tumor necrosis factor alpha (TNF) and endotoxin (ETX) on selected hemodynamic and glucoregulatory alterations was performed in conscious, unrestrained, adult male Holtzman rats. Rats with indwe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a0ae45866ed2dd488e714ab270bb6d13
https://pubmed.ncbi.nlm.nih.gov/2049814
https://pubmed.ncbi.nlm.nih.gov/2049814
Autor:
J. L. Hunth, J. P. Filkins
Publikováno v:
Shock. 3:1-2
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de48e90cc44831eda2ff8d691e0adf8
https://doi.org/10.1097/00024382-199506002-00004
https://doi.org/10.1097/00024382-199506002-00004
Autor:
J. P. Filkins, M. R. Yelich
Publikováno v:
American Journal of Physiology-Endocrinology and Metabolism. 239:E156-E161
Hyperinsulinemia subsequent to endotoxemia is a key factor leading to the disturbance of glucose homeostasis in endotoxin shock. This study investigated the mechanism(s) of hyperinsulinemia during endotoxicosis in the rat. Two primary mechanisms for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5014e2bb949c72231bf8d75d39ed7525
https://doi.org/10.1152/ajpendo.1980.239.2.e156
https://doi.org/10.1152/ajpendo.1980.239.2.e156
Publikováno v:
The American journal of physiology. 249(5 Pt 2)
Fasted mongrel dogs were anesthetized with pentobarbital sodium and instrumented for the on-line measurement of blood glucose (BG), a lead II electrocardiogram, and pressures in the left ventricle and pulmonary and systemic artery concomitant with on
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7178ecb7990f0164c6ec500b3d41a0e5
https://pubmed.ncbi.nlm.nih.gov/3904485
https://pubmed.ncbi.nlm.nih.gov/3904485