Zobrazeno 1 - 9 of 9 pro vyhledávání: '"J. P. E. Spencer"'
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Sulforaphane Protects Cortical Neurons against Endogenous Neurotoxins in a Model of Parkinson’s Disease
Autor: Patrizia Hrelia, J. Chirafisi, David Vauzour, J. P. E. Spencer, Cristina Angeloni, Giulia Corona, Silvana Hrelia, Katerina Vafeiadou, M. Buonfiglio
Publikováno v: Scopus-Elsevier
The endogenous neurotoxin 5-S-cysteinyl-dopamine (CysDA) has been linked to the degeneration of dopaminergic neurons in the Substantia nigra. Sulforaphane (SFN) is an isothiocyanate derived from cruciferous vegetables that has been proposed as a pote
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf8d437a4a4a538e11af1a41f441070c
http://hdl.handle.net/11585/365518
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3
Hydrogen peroxide induces oxidative DNA damage in rat type II pulmonary epithelial cells
Autor: J. P. E. Spencer, G. K. Ostrander, D. E. Rannels, Danny R. Welch, E. T. Knobbe, William J. Meehan
Publikováno v: Environmental and Molecular Mutagenesis. 33:273-278
Type II epithelial cells, which line the alveolar surface of the lung, are exposed to a variety of potentially mutagenic and carcinogenic insults. The purpose of this study was to determine if type II cells are susceptible to oxidative DNA damage in
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::db3424a107686df07d4e1a30d654bdfe
https://doi.org/10.1002/(sici)1098-2280(1999)33:4<273::aid-em3>3.0.co
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4
‘CO2-ligated’ cytochrome c oxidase: characterization and comparison with the Cl- -ligated enzyme
Autor: J. P. E. Spencer, Peter R. Rich, Ulrich Brandt, A. J. Moody, M. Richardson
Publikováno v: Biochemical Journal. 302:821-826
A form of fully oxidized bovine heart cytochrome c oxidase that is induced by CO2/HCO3- is described. The ligand-binding properties of this form are similar to those of Cl(-)-ligated oxidase [Moody, Cooper and Rich (1991) Biochim. Biophys. Acta 1059,
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eba95e092ab1b0138a5f55b3d442c908
https://doi.org/10.1042/bj3020821
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5
Neuroprotective actions of astaxanthin in cultured cortical neurones
Autor: A. Bourquin, David Vauzour, P. Jauregi, X. Ou, X. Li, J. P. E. Spencer
Publikováno v: Proceedings of the Nutrition Society. 70
Abundant evidence exists to suggest that increased oxidative stress may contribute to the neuropathology of age-related brain disorders such as Alzheimer’s and Parkinson’s diseases. Recently there has been an increased interest in the potential o
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::a6eec826b95820760936ff89d6838175
https://doi.org/10.1017/s0029665111002035
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8
Sulforaphane protects primary cortical neurons against 5-S-cysteinyl-dopamine-induced neurotoxicity
Autor: D. Vauzour, J. P. E. Spencer, ANGELONI, CRISTINA, HRELIA, SILVANA, HRELIA, PATRIZIA
The degeneration of dopaminergic neurons in the Substantia nigra has been linked to the formation of the endogenous neurotoxin 5-S-cysteinyl-dopamine. Sulforaphane (SFN), an isothiocyanate derived from the corresponding precursor glucosinolate found
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=od______4094::8f4f4dd88f6e409223405b924357a3ca
http://hdl.handle.net/11585/83368
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