Výsledky vyhledávání - "J. P. Donahue"

Akademický článek

Heterogeneous repolarization creates ventricular tachycardia circuits in healed myocardial infarction scar

Autor: Kamilla Kelemen, Ian D. Greener, Xiaoping Wan, Shankar Parajuli, J. Kevin Donahue

Publikováno v: Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)

Ventricular arrhythmias after heart attack are a leading cause of death. Here the authors show, in a porcine model, that KCNE3 and KCNE4 upregulation and a unique pattern of repolarization heterogeneity in the scar facilitate reentrant ventricular ta

Externí odkaz: https://doaj.org/article/b266107708554e1cbe599481b6c4a68b

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Akademický článek

Relations between plasma microRNAs, echocardiographic markers of atrial remodeling, and atrial fibrillation: Data from the Framingham Offspring study.

Autor: Aditya Vaze, Khanh-Van Tran, Kahraman Tanriverdi, Mayank Sardana, Darleen Lessard, J Kevin Donahue, Bruce Barton, Gerard Aurigemma, Steven A Lubitz, Honghuang Lin, George H Nasr, Amiya Mandapati, Emelia J Benjamin, Ramachandran S Vasan, Jane E Freedman, David D McManus

Publikováno v: PLoS ONE, Vol 15, Iss 8, p e0236960 (2020)

BackgroundCirculating microRNAs may reflect or influence pathological cardiac remodeling and contribute to atrial fibrillation (AF).ObjectiveThe purpose of this study was to identify candidate plasma microRNAs that are associated with echocardiograph

Externí odkaz: https://doaj.org/article/2e02f92b382946e9a14035522a92cb3f

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Functional analysis of iceA1, a CATG-recognizing restriction endonuclease gene in Helicobacter pylori

Autor: Richard J. Roberts, Geraldine G. Miller, Martin J. Blaser, J. P. Donahue, Richard D. Morgan, Qing Xu, L. J. van Doorn, Shuang-yong Xu

Publikováno v: Nucleic Acids Research. 30:3839-3847

iceA1 in Helicobacter pylori is a homolog of nlaIIIR, which encodes the CATG-specific restriction endonuclease NlaIII in Neisseria lactamica. Analysis of iceA1 sequences from 49 H.pylori strains shows that a full-length NlaIII-like ORF is present in

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de4a94e2caf33853a3aeeacdd9efd3f5
https://doi.org/10.1093/nar/gkf504

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Nucleotide-specific transcriptional pausing in the pyrBI leader region of Escherichia coli K-12

Autor: J P Donahue, Charles L. Turnbough

Publikováno v: Journal of Biological Chemistry. 269:18185-18191

Expression of the pyrBI operon, which encodes the subunits of the pyrimidine biosynthetic enzyme aspartate transcarbamylase, is regulated primarily through a UTP-sensitive transcriptional attenuation control mechanism in Escherichia coli. In this mec

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::6709eff72c369033ad076c484712b31f
https://doi.org/10.1016/s0021-9258(17)32433-x

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Genetic analysis of low V beta 3 expression in humans

Autor: John W. Kappler, C E Behrendt, J P Donahue, Philippa Marrack, Brian L. Kotzin, C Rittershaus, S Calaman, N S Ricalton

Publikováno v: The Journal of Experimental Medicine

While studying the T cell receptor (TCR) repertoire of normal individuals, we found that more than 20% of adults have low levels of circulating V beta 3.1+ T cells in both CD4 and CD8 populations. A similar frequency was found in fetal cord blood sam

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::48cef9ccbf6eee149539f437a0f0b8c9
http://europepmc.org/articles/PMC2191502

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Characterization of transcriptional initiation from promoters P1 and P2 of the pyrBI operon of Escherichia coli K12

Autor: Charles L. Turnbough, J P Donahue

Publikováno v: Journal of Biological Chemistry. 265:19091-19099

Expression of the pyrBI operon of Escherichia coli K12, which encodes the pyrimidine biosynthetic enzyme aspartate transcarbamylase, is negatively regulated by pyrimidine availability, primarily through an attenuation control mechanism, and also appe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::5ebee5434a73630f947e097abde55a65
https://doi.org/10.1016/s0021-9258(17)30629-4

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Regulation of NF-kappa B, AP-1, NFAT, and STAT1 nuclear import in T lymphocytes by noninvasive delivery of peptide carrying the nuclear localization sequence of NF-kappa B p50

Autor: T R, Torgerson, A D, Colosia, J P, Donahue, Y Z, Lin, J, Hawiger

Publikováno v: Journal of immunology (Baltimore, Md. : 1950). 161(11)

Activation of T lymphocytes by Ags or cytokines results in translocation of the transcription factors NF-kappa B, AP-1, NFAT, and STAT from the cytoplasm into the nucleus. The first step in the nuclear import process is recognition of a nuclear local

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::571a539c6491f91dd40ee5ea610e6050
https://pubmed.ncbi.nlm.nih.gov/9834092

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Adherence to gastric epithelial cells induces expression of a Helicobacter pylori gene, iceA, that is associated with clinical outcome

Autor: R M, Peek, S A, Thompson, J P, Donahue, K T, Tham, J C, Atherton, M J, Blaser, G G, Miller

Publikováno v: Proceedings of the Association of American Physicians. 110(6)

Most persons infected with Helicobacter pylori strains that produce vacuolating cytotoxin and possess cytotoxin-associated gene A (cagA) genotype nonetheless remain asymptomatic, suggesting that additional genes are important in virulence. We hypothe

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::19abb7db9d49bdedb77bf774309131e4
https://pubmed.ncbi.nlm.nih.gov/9824536

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