Zobrazeno 1 - 10
of 73
pro vyhledávání: '"J. P. Allison"'
Publikováno v:
Philosophical Transactions of the Royal Society A: Mathematical, Physical and Engineering Sciences. 380
We present an active exterior cloak for flexural waves propagating in a Kirchhoff plate of infinite extent. The evanescent multipole devices are characterized by Macdonald functions K n of the required order, which, assuming time-harmonic vibrations,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8554fb87d9f411421eeb6b0860f4024
https://doi.org/10.1098/rsta.2022.0072
https://doi.org/10.1098/rsta.2022.0072
Publikováno v:
The Journal of Immunology. 151:597-609
Mice homozygous for lpr and gld develop lymphadenopathy characterized by the progressive accumulation of an unusual population of CD4-, CD8-, CD2-, IL-2R- double-negative (DN) T cells that express reduced levels of TCR-alpha/beta, high levels of CD45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c84e599da0579ae5237877f6559b2538
https://doi.org/10.4049/jimmunol.151.2.597
https://doi.org/10.4049/jimmunol.151.2.597
Autor:
D Nandi, J P Allison
Publikováno v:
The Journal of Immunology. 147:1773-1778
T cells expressing alpha beta- and gamma delta-TCR are associated with the murine vaginal epithelium. A combination of phenotypic analysis of cell surface Ag and molecular analysis of the gamma- and delta-genes was used to demonstrate that vaginal ga
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d968ec0909a71e3426af1b1ebb285d9e
https://doi.org/10.4049/jimmunol.147.6.1773
https://doi.org/10.4049/jimmunol.147.6.1773
Publikováno v:
The Journal of Immunology. 146:2095-2101
Mutant T cell lines that do not express the endogenous alpha- and/or beta-chain genes of the TCR were generated from the alpha beta TCR/CD3+ tumor cell line C6VL with a combination of classical mutagenesis methods and selection of somatic hybrid vari
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de9d973571e4f512fac2266fc56e7d12
https://doi.org/10.4049/jimmunol.146.7.2095
https://doi.org/10.4049/jimmunol.146.7.2095
Autor:
A, van Elsas, R P, Sutmuller, A A, Hurwitz, J, Ziskin, J, Villasenor, J P, Medema, W W, Overwijk, N P, Restifo, C J, Melief, R, Offringa, J P, Allison
Publikováno v:
The Journal of Experimental Medicine
We have previously shown that small B16 melanomas can be successfully treated using a combination of anti-cytotoxic T lymphocyte antigen (CTLA)-4 monoclonal antibody with a granulocyte/macrophage colony-stimulating factor (GM-CSF) producing irradiate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ee924dc178288b2ef8ce824b6d57eb64
https://pubmed.ncbi.nlm.nih.gov/11514604
https://pubmed.ncbi.nlm.nih.gov/11514604
Autor:
A A, Hurwitz, B A, Foster, E D, Kwon, T, Truong, E M, Choi, N M, Greenberg, M B, Burg, J P, Allison
Publikováno v:
Cancer research. 60(9)
We have previously shown that antibodies to CTLA-4, an inhibitory receptor on T cells, can be effective at inducing regression of transplantable murine tumors. In this study, we demonstrate that an effective immune response against primary prostate t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::05a22137b8acbdc902c7eecf0a64bad0
https://pubmed.ncbi.nlm.nih.gov/10811122
https://pubmed.ncbi.nlm.nih.gov/10811122
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 162(10)
CTLA-4 engagement by mAbs inhibits, while CD28 enhances, IL-2 production and proliferation upon T cell activation. Here, we have analyzed the mechanisms involved in CTLA-4-mediated inhibition of T cell activation of naive CD4+ T cells using Ab cross-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::29b7e9251790767c7ce2a77aa8c0d14b
https://pubmed.ncbi.nlm.nih.gov/10229815
https://pubmed.ncbi.nlm.nih.gov/10229815
Publikováno v:
European journal of immunology. 28(10)
Negative as well as positive co-stimulation appears to play an important role in controlling T cell activation. CTLA-4 has been proposed to negatively regulate T cell responses. CTLA-4-deficient mice develop a lymphoproliferative disorder, initiated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ac45a91fb7a6fa7b32438812d29a662e
https://pubmed.ncbi.nlm.nih.gov/9808182
https://pubmed.ncbi.nlm.nih.gov/9808182
Autor:
J P, Allison, C, Chambers, A, Hurwitz, T, Sullivan, B, Boitel, S, Fournier, M, Brunner, M, Krummel
Publikováno v:
Novartis Foundation symposium. 215
Occupancy of the antigen receptor is not sufficient for activation of naïve T cells--additional co-stimulatory signals are required that can be provided only by 'professional' antigen-presenting cells. This two-signal model for T cell activation has
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::460faecda0e210f2c710396dec962979
https://pubmed.ncbi.nlm.nih.gov/9760573
https://pubmed.ncbi.nlm.nih.gov/9760573
Publikováno v:
International journal of cancer. 77(1)
In recent years, tumor immunotherapy has begun to exploit the emerging knowledge of the mechanisms of T cell activation to enhance the immune responses to tumors. However, many tumors, despite genetic modification to express co-stimulatory molecules
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::67d4d8020850a510bf961996664760cd
https://pubmed.ncbi.nlm.nih.gov/9639401
https://pubmed.ncbi.nlm.nih.gov/9639401