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Autor:
J. P. A. Bews, Victor J. Dzau, C. H. Heusser, Richard E. Pratt, Wen Min Zuo, M. M. De Gasparo
Publikováno v:
Hypertension. 19:249-254
We have identified and characterized an anti-human renin monoclonal antibody R1-20-5 that is selective for human active renin. R1-20-5 binds active renin with a dissociation constant (Kd) of 2.5 x 10(-7) M/l and inhibits renin enzymatic activity with