Zobrazeno 1 - 10
of 432
pro vyhledávání: '"J. Ovens"'
Autor:
Di Salvatore, Priore
Publikováno v:
Revista Uruguaya de Enfermería; ene-jun2021, Vol. 16 Issue 1, p1-11, 11p
Akademický článek
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Autor:
BRUYN, J.
Publikováno v:
Oud Holland, 1988 Jan 01. 102(4), 322-333.
Externí odkaz:
https://www.jstor.org/stable/42717447
Autor:
Philipp Rhein, Eric M. Desjardins, Ping Rong, Danial Ahwazi, Nicolas Bonhoure, Jens Stolte, Matthieu D. Santos, Ashley J. Ovens, Amy M. Ehrlich, José L. Sanchez Garcia, Qian Ouyang, Julian M. Yabut, Mads Kjolby, Mathieu Membrez, Niels Jessen, Jonathan S. Oakhill, Jonas T. Treebak, Pascal Maire, John W. Scott, Matthew J. Sanders, Patrick Descombes, Shuai Chen, Gregory R. Steinberg, Kei Sakamoto
Publikováno v:
Molecular Metabolism, Vol 51, Iss , Pp 101228- (2021)
Objective: The metabolic master-switch AMP-activated protein kinase (AMPK) mediates insulin-independent glucose uptake in muscle and regulates the metabolic activity of brown and beige adipose tissue (BAT). The regulatory AMPKγ3 isoform is uniquely
Externí odkaz:
https://doaj.org/article/c0481e7493a4441682f49290f3acce6a
Publikováno v:
BMJ Case Rep
A 49-year-old man presented with a 1-week history of abdominal pain, distension, diarrhoea and fatigue. CT of the abdomen and pelvis revealed peritonitis with no identifiable cause. Diagnostic laparoscopy was performed, which excluded gastrointestina
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55d7611a101ae621b024cba65ce55372
https://pubmed.ncbi.nlm.nih.gov/33853816
https://pubmed.ncbi.nlm.nih.gov/33853816
Akademický článek
Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
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Autor:
Ashley J. Ovens, Yi Sing Gee, Naomi X.Y. Ling, Dingyi Yu, Justin P. Hardee, Jin D. Chung, Kevin R.W. Ngoei, Nicholas J. Waters, Nolan J. Hoffman, John W. Scott, Kim Loh, Katrin Spengler, Regine Heller, Michael W. Parker, Gordon S. Lynch, Fei Huang, Sandra Galic, Bruce E. Kemp, Jonathan B. Baell, Jonathan S. Oakhill, Christopher G. Langendorf
Publikováno v:
The Biochemical journal. 479(11)
The AMP-activated protein kinase (AMPK) αβγ heterotrimer is a primary cellular energy sensor and central regulator of energy homeostasis. Activating skeletal muscle AMPK with small molecule drugs improves glucose uptake and provides an opportunity
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4af622cb195c6973f7a65b699182f0e7
https://pubmed.ncbi.nlm.nih.gov/35552369
https://pubmed.ncbi.nlm.nih.gov/35552369
Autor:
Priyanka Gupta, Keehn Strange, Rahul Telange, Ailan Guo, Heather Hatch, Amin Sobh, Jonathan Elie, Angela M. Carter, John Totenhagen, Chunfeng Tan, Yogesh A. Sonawane, Jiri Neuzil, Amarnath Natarajan, Ashley J. Ovens, Jonathan S. Oakhill, Thorsten Wiederhold, Karel Pacak, Hans K. Ghayee, Laurent Meijer, Sushanth Reddy, James A. Bibb
Publikováno v:
Cell Rep
SUMMARYMetabolic dysfunction mutations can impair energy sensing and cause cancer. Loss of function of mitochondrial TCA cycle enzyme, succinate dehydrogenase B (SDHB) results in various forms of cancer typified by pheochromocytoma (PC). Here we deli
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cd56e70ddf59494d8509fea21a0a5641
https://doi.org/10.2139/ssrn.4018612
https://doi.org/10.2139/ssrn.4018612
Autor:
Katyayanee Neopane, Natalie Kozlov, Florentina Negoita, Lisa Murray-Segal, Robert Brink, Ashfaqul Hoque, Ashley J. Ovens, Gavin Tjin, Luke M. McAloon, Dingyi Yu, Naomi X.Y. Ling, Matthew J. Sanders, Jonathan S. Oakhill, John W. Scott, Gregory R. Steinberg, Kim Loh, Bruce E. Kemp, Kei Sakamoto, Sandra Galic
Publikováno v:
Neopane, K, Kozlov, N, Negoita, F, Murray-Segal, L, Brink, R, Hoque, A, Ovens, A J, Tjin, G, McAloon, L M, Yu, D, Ling, N X Y, Sanders, M J, Oakhill, J S, Scott, J W, Steinberg, G R, Loh, K, Kemp, B E, Sakamoto, K & Galic, S 2022, ' Blocking AMPK β1 myristoylation enhances AMPK activity and protects mice from high-fat diet-induced obesity and hepatic steatosis ', Cell Reports, vol. 41, no. 12, 111862 . https://doi.org/10.1016/j.celrep.2022.111862
AMP-activated protein kinase (AMPK) is a master regulator of cellular energy homeostasis and a therapeutic target for metabolic diseases. Co/post-translational N-myristoylation of glycine-2 (Gly2) of the AMPK β subunit has been suggested to regulate
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::785ffb05621c50ca77add3fec7ae522a
https://curis.ku.dk/ws/files/333631148/1_s2.0_S2211124722017582_main.pdf
https://curis.ku.dk/ws/files/333631148/1_s2.0_S2211124722017582_main.pdf
Autor:
Bruce E. Kemp, John W. Scott, Ashley J. Ovens, William J. Smiles, Christopher G. Langendorf, Naomi X.Y. Ling, Dingyi Yu, Ashfaqul Hoque, Kaitlin R. Morrison, Sandra Galic, Jonathan S. Oakhill, Janni Peterson
AMPK and mTORC1 are nutrient-sensitive protein kinases that form a fundamental negative feedback loop that governs cell growth and proliferation. AMPK is an αβγ heterotrimer that is directly phosphorylated by mTORC1 on α2S345 to suppress AMPK act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b2d19447c08856907488b14a7c4a5309
https://doi.org/10.1101/2021.10.20.462995
https://doi.org/10.1101/2021.10.20.462995