Zobrazeno 1 - 10
of 107
pro vyhledávání: '"J. Olnes"'
Autor:
Richard Apps, Angélique Biancotto, Julián Candia, Yuri Kotliarov, Shira Perl, Foo Cheung, Rohit Farmer, Matthew P. Mulè, Nicholas Rachmaninoff, Jinguo Chen, Andrew J. Martins, Rongye Shi, Huizhi Zhou, Neha Bansal, Paula Schum, Matthew J. Olnes, Pedro Milanez-Almeida, Kyu Lee Han, Brian Sellers, Mario Cortese, Thomas Hagan, Nadine Rouphael, Bali Pulendran, Lisa King, Jody Manischewitz, Surender Khurana, Hana Golding, Robbert G. van der Most, Howard B. Dickler, Ronald N. Germain, Pamela L. Schwartzberg, John S. Tsang
Publikováno v:
Cell Reports, Vol 43, Iss 9, Pp 114706- (2024)
Summary: To gain insight into how an adjuvant impacts vaccination responses, we use systems immunology to study human H5N1 influenza vaccination with or without the adjuvant AS03, longitudinally assessing 14 time points including multiple time points
Externí odkaz:
https://doaj.org/article/68501964c395404e9b87d185f2d87bdb
Autor:
Alana Vicente, Bhavisha A. Patel, Fernanda Gutierrez-Rodrigues, Emma Groarke, Valentina Giudice, Jennifer Lotter, Xingmin Feng, Sachiko Kajigaya, Barbara Weinstein, Evette Barranta, Matthew J. Olnes, Ankur R. Parikh, Maher Albitar, Colin O. Wu, Ruba Shalhoub, Katherine R. Calvo, Danielle M. Townsley, Phillip Scheinberg, Cynthia E. Dunbar, Neal S. Young, Thomas Winkler
Publikováno v:
Haematologica, Vol 105, Iss 12 (2020)
Myelodysplastic syndromes (MDS) are a group of clonal myeloid disorders characterized by cytopenia and a propensity to develop acute myeloid leukemia (AML). The management of lower-risk (LR) MDS with persistent cytopenias remains suboptimal. Eltrombo
Externí odkaz:
https://doaj.org/article/d39465a6ea80433faa1359329e4d1aed
Autor:
Lori T. Quakenbush, A. L. Von Duyke, Justin A. Crawford, John J. Citta, Greg A. Breed, J. Olnes, Matthew L. Druckenmiller
Publikováno v:
Marine Ecology Progress Series. 661:229-242
Significant reductions in sea ice in the Pacific Arctic have occurred over the last 2 decades. Comparing the results of similarly conducted studies, but from different time periods, can increase our understanding of how marine mammals are responding
Autor:
Matthew J. Olnes, Holly A. Martinson
Publikováno v:
Cancer gene therapy
Gastric cancer (GC) is an aggressive malignancy that is the third leading cause of cancer mortality worldwide. Localized GC can be cured with surgery, but most patients present with more advanced non-operable disease. Until recently, treatment option
Autor:
Justin A. Crawford, A. L. Von Duyke, Matthew L. Druckenmiller, Lori T. Quakenbush, John J. Citta, J. Olnes
Publikováno v:
Polar Biology. 43:1307-1320
Bearded seals (Erignathus barbatus) are abundant in the Pacific Arctic and are an important subsistence resource for many Alaska Native communities. The Pacific Arctic is warming rapidly with substantial consequences predicted for ice-associated mari
Publikováno v:
Cancers, Vol 13, Iss 5026, p 5026 (2021)
Cancers
Cancers
Simple Summary Myelodysplastic syndromes (MDS) and acute myeloid leukemia (AML) are bone marrow cancers that have a poor prognosis. They have traditionally been treated with chemotherapy with limited success, and stem cell transplant, which many pati
Autor:
Angelique Biancotto, Abigail Wank, Shira Perl, Wendell Cook, Matthew J Olnes, Pradeep K Dagur, J Christopher Fuchs, Marc Langweiler, Ena Wang, J Philip McCoy
Publikováno v:
PLoS ONE, Vol 10, Iss 7, p e0132870 (2015)
Externí odkaz:
https://doaj.org/article/57763547bf3a4f4d9d8bda3c2916798f
Autor:
Ronan Desmond, Julie Thompson, Matthew J. Olnes, Phillip Scheinberg, Catherine Lai, Colin Wu, Ankur R. Parikh, Vishal Ranpura, Aarthi Shenoy, Barbara Weinstein, A. John Barrett, Christopher S. Hourigan, Neal S. Young
Publikováno v:
Blood Advances. 3:980-983
TO THE EDITOR: Treatment of myelodysplastic syndrome (MDS) is suboptimal. Responses to hematopoietic growth factors, hypomethylating agents, and lenalidomide in 5q− syndromes are not sustained, and not all patients benefit. Allogeneic stem cell tra
Publikováno v:
Best practiceresearch. Clinical haematology. 34(2)
Bone marrow failure is characterized by a disruption of hematopoietic stem cell (HSC) homeostasis and function, which causes decreased blood counts. Germline and somatic mutations within HSCs and immune dysregulation contribute to the pathogenesis of
Autor:
Matthew J. Olnes
Publikováno v:
Cancers, Vol 13, Iss 295, p 295 (2021)
Cancers
Cancers
The era of immunotherapy for hematologic malignancies began with the first allogeneic hematopoietic stem cell transplant (HSCT) study published by E [...]