539. Impact of a Rapid Diagnostic Assay for the Detection of Bacterial and Viral Agents on Antimicrobial use in Critically Ill Patients with Pneumonia

Autor: Lionel K Sielatchom Noubissie, Zachary Ciochetto, Emily Willey, Deanna Olexia, Magdalena Wrzesinski, Blake W Buchan, J Njeri Wainaina, Allison Gibble

Publikováno v: Open Forum Infectious Diseases. 9

Background Conventional diagnostic methods for pneumonia have a long turnaround time, and a pathogen is isolated in only 33% of cases. As a result, empiric therapy with broad-spectrum antimicrobials often becomes definitive therapy. Rapid molecular d

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::f6c22c5fc3ac5c62ab8df752c3e32748
https://doi.org/10.1093/ofid/ofac492.592

Eruptive Xanthoma During Antiretroviral Therapy

Autor: Olushola L. Akinshemoyin Vaughn, Kenneth B. Gordon, J. Njeri Wainaina

Publikováno v: Volume: 09, Issue: 01 43-45
Journal of Microbiology and Infectious Diseases
Journal of Microbiology and Infectious Diseases, Vol 09, Iss 01, Pp 43-45 (2019)

We present a case of eruptive xanthoma in a man living with HIV after changing antiretroviral therapy. People living with HIV are at increased risk of dyslipidemia due to the infection itself and the use of antiretroviral medications. Prompt recognit

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3bb7b00d47a903465fe2b901ce09cf91
https://doi.org/10.5799/jmid.537168

A multicentre stewardship initiative to decrease excessive duration of antibiotic therapy for the treatment of community-acquired pneumonia

Autor: Gregory A. Eschenauer, Vincent D. Marshall, Sara Revolinski, Jerod Nagel, Tejal K. Gandhi, Lindsay Colyer, Twisha S Patel, Julius Li, Angela M. Huang, J Njeri Wainaina, Jessica Grieger, Megan Lim, Cynthia T Nguyen, Farnaz Foolad, Megan Mack

Publikováno v: The Journal of antimicrobial chemotherapy. 73(5)

Background The increased emphasis on pneumonia-related performance measures and patient outcomes has led hospitals to implement multifaceted approaches to quickly identify patients with community-acquired pneumonia (CAP), start timely therapy and red

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::21ae6abc406db524f93a296247bb7866
https://pubmed.ncbi.nlm.nih.gov/29462306

A Multicenter Stewardship Initiative to Decrease Excessive Duration of Antibiotic Therapy for the Treatment of Community-Acquired Pneumonia (CAP)

Autor: J Njeri Wainaina, Julius Li, Megan Lim, Tejal K. Gandhi, Sara Revolinski, Jessica Grieger, Cynthia Nguyen, Twisha S Patel, Angela Huang, Farnaz Foolad, Lindsay Colyer, Jerod Nagel, Vince Marshall, Megan Mack, Gregory A. Eschenauer

Publikováno v: Open Forum Infectious Diseases. 4:S63-S64

Background Hospitals have implemented multifaceted approaches to quickly identify CAP, start timely therapy, and reduce hospital readmission, yet there has been minimal focus on providing appropriate duration of therapy. The IDSA CAP guidelines recom

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c84db0d1916e75f3d5bd67c6f4c1973e
https://doi.org/10.1093/ofid/ofx162.151

A Single-center, Quasi-experimental Study to Evaluate the Impact of a Multiplex Polymerase Chain Reaction System Combined with Antimicrobial Stewardship Intervention on Time to Targeted Therapy in Patients with Suspected Central Nervous System Infection

Autor: Kelsey Powell, Sara Revolinski, Angela Huang, J Njeri Wainaina, Anne Daniels, Allison Gibble

Publikováno v: Open Forum Infectious Diseases

Background Empiric treatment for central nervous system (CNS) infections consists of coverage with multiple antimicrobial agents that may be continued until a pathogen can be identified. Identification may take significant time to result, leading to

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4c5beabf09f46a9fe58d4b8c75899e0
http://europepmc.org/articles/PMC5631901