Zobrazeno 1 - 10
of 77
pro vyhledávání: '"J. Niederhuber"'
Autor:
Alexander D. Naydich, Shannon N. Nangle, Johannes J. Bues, Disha Trivedi, Nabeel Nissar, Mara C. Inniss, Matthew J. Niederhuber, Jeffrey C. Way, Pamela A. Silver, David T. Riglar
Publikováno v:
mSystems, Vol 4, Iss 4 (2019)
ABSTRACT Engineering synthetic circuits into intestinal bacteria to sense, record, and respond to in vivo signals is a promising new approach for the diagnosis, treatment, and prevention of disease. However, because the design of disease-responsive c
Externí odkaz:
https://doaj.org/article/a670a59b6f6541ef8395330c64f5fd82
Autor:
S. Jordan Kerns, Jeffrey C. Way, David T. Riglar, Roderick T. Bronson, Jonathan W. Kotula, Pamela A. Silver, Matthew J. Niederhuber, Tobias W. Giessen, Michael H. Baym, Georg K. Gerber
Publikováno v:
Nature Biotechnology. 35:653-658
Bacteria can be engineered to function as diagnostics or therapeutics in the mammalian gut but commercial translation of technologies to accomplish this has been hindered by the susceptibility of synthetic genetic circuits to mutation and unpredictab
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd7b33f15de79d7c0a05737492e84214
https://doi.org/10.1038/nbt.3879
https://doi.org/10.1038/nbt.3879
How temporal cues combine with spatial inputs to control gene expression during development is poorly understood. Here, we test the hypothesis that theDrosophilatranscription factor E93 controls temporal gene expression by regulating chromatin access
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b5fee931d6333baa10254cb5d005e29c
Publikováno v:
Development
How temporal cues combine with spatial inputs to control gene expression during development is poorly understood. Here, we test the hypothesis that the Drosophila transcription factor E93 controls temporal gene expression by regulating chromatin acce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7de041ad3ea2a8306729694f57dc9982
https://pubmed.ncbi.nlm.nih.gov/32094114
https://pubmed.ncbi.nlm.nih.gov/32094114
Autor:
Spencer L. Nystrom, Daniel J. McKay, Yiqin Ma, Matthew J. Niederhuber, Laura Buttitta, Christopher M. Uyehara, Mary Leatham-Jensen
Publikováno v:
Genesdevelopment. 31(9)
Specification of tissue identity during development requires precise coordination of gene expression in both space and time. Spatially, master regulatory transcription factors are required to control tissue-specific gene expression programs. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3390cec41216a0d61880b9771ae8e02d
https://pubmed.ncbi.nlm.nih.gov/28566535
https://pubmed.ncbi.nlm.nih.gov/28566535
Publikováno v:
Molecular Biology of the Cell
Application of 3D-structured illumination microscopy to study the protein organization of the β-carboxysome in Synechococcus elongatus reveals new structural details of this bacterial microcompartment and the feasibility of using superresolution mic
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e56c379cf47bacfc5d42c7390d92254c
https://pubmed.ncbi.nlm.nih.gov/28963440
https://pubmed.ncbi.nlm.nih.gov/28963440
Carbon fixation in cyanobacteria makes a major contribution to the global carbon cycle. The cyanobacterial carboxysome is a proteinaceous microcompartment that protects and concentrates the carbon-fixing enzyme RuBisCO in a paracrystalline lattice, m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02e4ab973b83f3d19f70ce961eb73dde
Autor:
Pamela A. Silver, S. Jordan Kerns, Michael H. Baym, Roderick T. Bronson, David T. Riglar, Georg K. Gerber, Jonathan W. Kotula, Jeffrey C. Way, Matthew J. Niederhuber
Inflammation in the gut, caused by infection and autoimmunity, remains challenging to effectively detect, monitor, and treat. Here, we engineer a commensal mouse E. coli strain to record exposure to tetrathionate, a downstream product of reactive oxy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f805c54081f5c0df923683a8903675a6
Autor:
M. Malicdan, T. Vilboux, B. Ben-Zeev, J. Guo, A. Eliyahu, B. Pode-Shakked, A. Dori, S. Kakani, S. Chandrasekharappa, C. Ferreira, N. Shelestovich, D. Marek-Yagel, H. Pri-Chen, I. Blat, J. Niederhuber, C. Toro, J. Deeken, T. Yardeni, D. Wallace, W. Gahl, Y. Anikster
Publikováno v:
Neuromuscular Disorders. 27:S176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::888c25ce0b002b1ea13bb7a8dada2065
https://doi.org/10.1016/j.nmd.2017.06.302
https://doi.org/10.1016/j.nmd.2017.06.302
Publikováno v:
Geburtshilfe und Frauenheilkunde. 68
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::2c0635f107f06eee0204a6cfbe78deb8
https://doi.org/10.1055/s-0028-1089160
https://doi.org/10.1055/s-0028-1089160