Zobrazeno 1 - 10
of 3 889
pro vyhledávání: '"J. Nicholls"'
Saliva-derived DNA is suitable for the detection of clonal haematopoiesis of indeterminate potential
Autor:
Robert L. O’Reilly, Jared Burke, Philip Harraka, Paul Yeh, Kerryn Howlett, Kiarash Behrouzfar, Amanda Rewse, Helen Tsimiklis, Graham G. Giles, Kristen J. Bubb, Stephen J. Nicholls, Roger L. Milne, Melissa C. Southey
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Clonal haematopoiesis of indeterminate potential (CHIP) has been associated with many adverse health outcomes. However, further research is required to understand the critical genes and pathways relevant to CHIP subtypes, evaluate how CHIP c
Externí odkaz:
https://doaj.org/article/b2a9bf94ecc947d4b3110fe24a50ccfd
Autor:
Anna E. Williamson, Sanuri Liyanage, Mohammadhossein Hassanshahi, Malathi S. I. Dona, Deborah Toledo-Flores, Dang X. A. Tran, Catherine Dimasi, Nisha Schwarz, Sanuja Fernando, Thalia Salagaras, Aaron Long, Jan Kazenwadel, Natasha L. Harvey, Grant R. Drummond, Antony Vinh, Vashe Chandrakanthan, Ashish Misra, Zoltan Neufeld, Joanne T. M. Tan, Luciano Martelotto, Jose M. Polo, Claudine S. Bonder, Alexander R. Pinto, Shiwani Sharma, Stephen J. Nicholls, Christina A. Bursill, Peter J. Psaltis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-21 (2024)
Abstract Converging evidence indicates that extra-embryonic yolk sac is the source of both macrophages and endothelial cells in adult mouse tissues. Prevailing views are that these embryonically derived cells are maintained after birth by proliferati
Externí odkaz:
https://doaj.org/article/d2b62685f49a4c7f8deedee2fe7c08c9
Autor:
Yu Kataoka, Satoshi Kitahara, Sayaka Funabashi, Hisashi Makino, Masaki Matsubara, Miki Matsuo, Yoko Omura-Ohata, Ryo Koezuka, Mayu Tochiya, Tamiko Tamanaha, Tsutomu Tomita, Kyoko Honda-Kohmo, Michio Noguchi, Kota Murai, Kenichiro Sawada, Takamasa Iwai, Hideo Matama, Satoshi Honda, Masashi Fujino, Kazuhiro Nakao, Shuichi Yoneda, Kensuke Takagi, Fumiyuki Otsuka, Yasuhide Asaumi, Kiminori Hosoda, Stephen J. Nicholls, Satoshi Yasuda, Teruo Noguchi
Publikováno v:
Atherosclerosis Plus, Vol 56, Iss , Pp 1-6 (2024)
Background and aims: Randomized clinical trials have demonstrated the ability of glucagon-like peptide-1 analogues (GLP-1RAs) to reduce atherosclerotic cardiovascular disease events in patients with type 2 diabetes (T2D). How GLP-1RAs modulate diabet
Externí odkaz:
https://doaj.org/article/409a421a06d648bab589ebcb9fd6fd88
Autor:
Sarah R. Monagle, Ella Spear, Timothy Abrahams, Udit Thakur, Derk Pol, Karen Bellamy, Joanne Hickman, Stephen J. Nicholls, Adam J. Nelson
Publikováno v:
American Journal of Preventive Cardiology, Vol 19, Iss , Pp 100716- (2024)
Seasonal influenza immunization reduces the risk of cardiovascular events. Patients with established cardiovascular disease (CVD) derive a greater benefit than those without, yet up to 50 % do not take up the immunization. Patient perceptions and bel
Externí odkaz:
https://doaj.org/article/d3912409bcfd4b12bd892b7f5a9bbdf5
Autor:
Rémi Thiéblemont, Gonéri Le Cozannet, Robert J. Nicholls, Jérémy Rohmer, Guy Wöppelmann, Daniel Raucoules, Marcello deMichele, Alexandra Toimil, Daniel Lincke
Publikováno v:
Earth's Future, Vol 12, Iss 8, Pp n/a-n/a (2024)
Abstract Beside climate‐change‐induced sea‐level rise (SLR), land subsidence can strongly amplify coastal risk in flood‐prone areas. Mapping and quantifying contemporary vertical land motion (VLM) at continental scales has long been a challen
Externí odkaz:
https://doaj.org/article/199097f9c039421cb85c8ec41e4e7bdc
Autor:
Stephen T. Vernon, Stuart Brentnall, Danielle J Currie, Cindy Peng, Michael P. Gray, Giordano Botta, Deo Mujwara, Stephen J. Nicholls, Stuart M. Grieve, Julie Redfern, Clara Chow, Jean-Frederic Levesque, Peter J. Meikle, Garry Jennings, Zanfina Ademi, Andrew Wilson, Gemma A. Figtree
Publikováno v:
American Journal of Preventive Cardiology, Vol 18, Iss , Pp 100672- (2024)
Background: Primary prevention programs utilising traditional risk scores fail to identify all individuals who suffer acute cardiovascular events. We aimed to model the impact and cost effectiveness of incorporating a Polygenic risk scores (PRS) into
Externí odkaz:
https://doaj.org/article/b786deb82829480a8118d138be0a781e
Autor:
Paula Camus, Ivan D. Haigh, Niall Quinn, Thomas Wahl, Thomas Benson, Ben Gouldby, Ahmed A. Nasr, Md Mamunur Rashid, Alejandra R. Enríquez, Stephen E. Darby, Robert J. Nicholls, Norberto C. Nadal-Caraballo
Publikováno v:
Weather and Climate Extremes, Vol 44, Iss , Pp 100662- (2024)
Storm surges are the most important driver of flooding in many coastal areas. Understanding the spatial extent of storm surge events has important financial and practical implications for flood risk management, reinsurance, infrastructure reliability
Externí odkaz:
https://doaj.org/article/921034d371aa4a73bba47e75b95020da
Autor:
Stephen J. Nicholls, Santiago Tofé, Carel W. le Roux, David A. D’Alessio, Russell J. Wiese, Imre Pavo, Katelyn Brown, Govinda J. Weerakkody, Meltem Zeytinoglu, Irene C. Romera
Publikováno v:
Cardiovascular Diabetology, Vol 23, Iss 1, Pp 1-15 (2024)
Abstract Background Metabolic syndrome is characterized as the co-occurrence of interrelated cardiovascular risk factors, including insulin resistance, hyperinsulinemia, abdominal obesity, dyslipidemia and hypertension. Once weekly tirzepatide is app
Externí odkaz:
https://doaj.org/article/fe7b1924c64f4aba90d45911656869ae
Autor:
Daniella Hirschfeld, Ray Boyle, Robert J. Nicholls, David Behar, Miguel Esteban, Jochen Hinkel, Gordon Smith, David J. Hanslow
Publikováno v:
Climate Services, Vol 34, Iss , Pp 100452- (2024)
Climate-induced sea-level rise threatens the world’s coastal populations, critical infrastructure, and ecosystems. The science of sea-level rise (SLR) has developed to inform understanding of global climate mitigation and adaptation challenges, but
Externí odkaz:
https://doaj.org/article/dbd023dfc0db491ebc6a4cd8bddc4124
Autor:
Massimo Imazio, Allan L. Klein, Antonio Brucato, Antonio Abbate, Michael Arad, Paul C. Cremer, Antonella Insalaco, Martin M. LeWinter, Basil S. Lewis, David Lin, Sushil A. Luis, Stephen J. Nicholls, Paul Sutej, Yishay Wasserstrum, JoAnn Clair, Indra Agarwal, Sheldon Wang, John F. Paolini
Publikováno v:
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, Vol 13, Iss 6 (2024)
Background Rilonacept, a once‐weekly interleukin‐1 alpha and beta cytokine trap, reduced pericarditis recurrence in the phase 3 study, RHAPSODY (Rilonacept Inhibition of Interleukin‐1 Alpha and Beta for Recurrent Pericarditis: A Pivotal Symptom
Externí odkaz:
https://doaj.org/article/5b697727911f4cb89e0bb7e5b20b9221