Zobrazeno 1 - 10
of 85
pro vyhledávání: '"J. Newey"'
Autor:
Kate E Lines, Mahsa Javid, Anita A C Reed, Gerard V Walls, Mark Stevenson, Michelle Simon, Kreepa G Kooblall, Sian E Piret, Paul T Christie, Paul J Newey, Ann-Marie Mallon, Rajesh V Thakker
Publikováno v:
Endocrine Connections, Vol 9, Iss 5, Pp 426-437 (2020)
Multiple endocrine neoplasia type 1 (MEN1), an autosomal domina nt disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreati c and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroi dis
Externí odkaz:
https://doaj.org/article/a2653ed4f925427ab63aff57abcabec7
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
Context Previous studies, including our own, have demonstrated a highly variable incidence of primary hyperparathyroidism (PHPT) from year to year. Objective We planned to provide a current estimate of the incidence and prevalence of PHPT in a commun
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8123e694695c4ba0ce537491f74c89d9
https://doi.org/10.1210/clinem/dgad201
https://doi.org/10.1210/clinem/dgad201
Publikováno v:
Journal of Molecular Endocrinology. 70
The prolactin receptor (PRLR) signals predominantly through the JAK2-STAT5 pathway regulating multiple physiological functions relating to fertility, lactation, and metabolism. However, the molecular pathology and role of PRLR mutations and signallin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef6f24ff74193dfec778db1243c5a2bf
https://doi.org/10.1530/jme-22-0164
https://doi.org/10.1530/jme-22-0164
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism.
ContextPrimary hyperparathyroidism (PHPT) is associated with increased risk of morbidity and death, and vitamin D levels are a potentially confounding variable.ObjectiveThe aim of this study was to assess morbidity and mortality associated with prima
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34e8aad9e690284569e84ff91da28567
https://doi.org/10.1210/clinem/dgad103
https://doi.org/10.1210/clinem/dgad103
Autor:
Paul J. Newey
Publikováno v:
Endocrinology and Metabolism Clinics of North America. 50:663-681
Primary hyperparathyroidism (PHPT) is a commonly encountered clinical problem and occurs as part of an inherited disorder in ∼10% of patients. Several features may alert the clinician to the possibility of a hereditary PHPT disorder (eg, young age
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c29ec6ab2af9fe76338c93883680cf21
https://doi.org/10.1016/j.ecl.2021.08.003
https://doi.org/10.1016/j.ecl.2021.08.003
Autor:
Paul J. Newey
Publikováno v:
Medicine. 49:539-543
Multiple endocrine neoplasia (MEN) describes the occurrence of tumours affecting two or more endocrine glands in one patient. Two main forms are recognized: MEN type 1 (MEN1) and type 2 (MEN2). MEN1 is characterized by the combined occurrence of para
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8cf04867bca4d77e11edd6155287db3
https://doi.org/10.1016/j.mpmed.2021.06.003
https://doi.org/10.1016/j.mpmed.2021.06.003
Autor:
Enrique Soto-Pedre, Paul J Newey, Sundararajan Srinivasan, Moneeza K Siddiqui, Colin N A Palmer, Graham P Leese
Publikováno v:
The Journal of clinical endocrinology and metabolism. 107(12)
Context A hypothesis-free genetic association analysis has not been reported for patients with primary hyperparathyroidism (PHPT). Objective We aimed to investigate genetic associations with PHPT using both genome-wide association study (GWAS) and ca
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b799f75df2f0334a187b526fd294b432
https://pubmed.ncbi.nlm.nih.gov/36102151
https://pubmed.ncbi.nlm.nih.gov/36102151
Autor:
Anita A C Reed, Mahsa Javid, Mark Stevenson, Paul T. Christie, Rajesh V. Thakker, Paul J. Newey, Michelle Simon, Ann-Marie Mallon, Sian E. Piret, Kate E Lines, Gerard V Walls, Kreepa Kooblall
Publikováno v:
Endocrine Connections
Endocrine Connections, Vol 9, Iss 5, Pp 426-437 (2020)
Endocrine Connections, Vol 9, Iss 5, Pp 426-437 (2020)
Multiple endocrine neoplasia type 1 (MEN1), an autosomal dominant disorder caused by MEN1 germline mutations, is characterised by parathyroid, pancreatic and pituitary tumours. MEN1 mutations also cause familial isolated primary hyperparathyroidism (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::257952e5a3e0a58d82996a11600ae016
http://europepmc.org/articles/PMC7274560
http://europepmc.org/articles/PMC7274560
Publikováno v:
Clinical endocrinologyREFERENCES. 97(4)
Disorders of calcium homeostasis are the most frequent metabolic bone and mineral disease encountered by endocrinologists. These disorders usually manifest as primary hyperparathyroidism (PHPT) or hypoparathyroidism (HP), which have a monogenic aetio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ebe871ccadfc3fd93c29eec467b1cc12
https://pubmed.ncbi.nlm.nih.gov/34935164
https://pubmed.ncbi.nlm.nih.gov/34935164
Autor:
Paul J Newey, John Newell-Price
Publikováno v:
Journal of the Endocrine Society
Clinical practice guidelines for patients with multiple endocrine neoplasia type 1 (MEN1) recommend a variety of surveillance options. Given progress over the past decade in this area, it is timely to evaluate their ongoing utility. MEN1 is character
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::55b439d73a591d8a751000cc631c664f
https://pubmed.ncbi.nlm.nih.gov/35079671
https://pubmed.ncbi.nlm.nih.gov/35079671