Zobrazeno 1 - 10
of 563
pro vyhledávání: '"J. Nabel"'
Autor:
J. Wang, N. Zeng, M. Wang, F. Jiang, J. Chen, P. Friedlingstein, A. K. Jain, Z. Jiang, W. Ju, S. Lienert, J. Nabel, S. Sitch, N. Viovy, H. Wang, A. J. Wiltshire
Publikováno v:
Atmospheric Chemistry and Physics, Vol 18, Pp 10333-10345 (2018)
El Niño has two different flavors, eastern Pacific (EP) and central Pacific (CP) El Niños, with different global teleconnections. However, their different impacts on the interannual carbon cycle variability remain unclear. Here we compared the b
Externí odkaz:
https://doaj.org/article/290537c9694f474997580a429cc7a1db
Autor:
Wanwisa Promsote, Ling Xu, Jason Hataye, Giulia Fabozzi, Kylie March, Cassandra G. Almasri, Megan E. DeMouth, Sarah E. Lovelace, Chloe Adrienna Talana, Nicole A. Doria-Rose, Krisha McKee, Sabrina Helmold Hait, Joseph P. Casazza, David Ambrozak, Jochen Beninga, Ercole Rao, Norbert Furtmann, Joerg Birkenfeld, Elizabeth McCarthy, John-Paul Todd, Constantinos Petrovas, Mark Connors, Andrew T. Hebert, Jeremy Beck, Junqing Shen, Bailin Zhang, Mikhail Levit, Ronnie R. Wei, Zhi-yong Yang, Amarendra Pegu, John R. Mascola, Gary J. Nabel, Richard A. Koup
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Agents that can simultaneously activate latent HIV, increase immune activation and enhance the killing of latently-infected cells represent promising approaches for HIV cure. Here, we develop and evaluate a trispecific antibody (Ab), N6/αCD
Externí odkaz:
https://doaj.org/article/8e5eb98b4e8744a192139410ac1ac511
Autor:
Jennifer N. Rainho-Tomko, Vincent Pavot, Michael Kishko, Kurt Swanson, Darin Edwards, Heesik Yoon, Lilibeth Lanza, Judith Alamares-Sapuay, Robert Osei-Bonsu, Sophia T. Mundle, Dave A. Murison, Scott Gallichan, Simon Delagrave, Chih-Jen Wei, Linong Zhang, Gary J. Nabel
Publikováno v:
npj Vaccines, Vol 7, Iss 1, Pp 1-9 (2022)
Abstract Respiratory syncytial virus (RSV) G glycoprotein has recently reemerged as a vaccine antigen due to its ability to elicit potent neutralizing antibodies and ameliorate disease in animal models. Here we designed three constructs to display th
Externí odkaz:
https://doaj.org/article/ebfed4caf551425eb43d4a04f2b4e65f
Autor:
Jennifer Cable, Siddharth Balachandran, Lisa P. Daley‐Bauer, Arjun Rustagi, Ferrin Antony, Justin J. Frere, Jamie Strampe, Katherine Kedzierska, Judy L. Cannon, Maureen A. McGargill, Daniela Weiskopf, Robert C. Mettelman, Julia Niessl, Paul G. Thomas, Bryan Briney, Sophie A. Valkenburg, Jesse D. Bloom, Pamela J. Bjorkman, Sho Iketani, C. Garrett Rappazzo, Chelsea M. Crooks, Kali F. Crofts, Stefan Pöhlmann, Florian Krammer, Andrea J. Sant, Gary J. Nabel, Stacey Schultz‐Cherry
Publikováno v:
Annals of the New York Academy of Sciences. 1521:32-45
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::17ae512b46e8bbda4f04547ea661655b
https://doi.org/10.1111/nyas.14960
https://doi.org/10.1111/nyas.14960
Autor:
Kevin O. Saunders, Nathan I. Nicely, Kevin Wiehe, Mattia Bonsignori, R. Ryan Meyerhoff, Robert Parks, William E. Walkowicz, Baptiste Aussedat, Nelson R. Wu, Fangping Cai, Yusuf Vohra, Peter K. Park, Amanda Eaton, Eden P. Go, Laura L. Sutherland, Richard M. Scearce, Dan H. Barouch, Ruijun Zhang, Tarra Von Holle, R. Glenn Overman, Kara Anasti, Rogier W. Sanders, M. Anthony Moody, Thomas B. Kepler, Bette Korber, Heather Desaire, Sampa Santra, Norman L. Letvin, Gary J. Nabel, David C. Montefiori, Georgia D. Tomaras, Hua-Xin Liao, S. Munir Alam, Samuel J. Danishefsky, Barton F. Haynes
Publikováno v:
Cell Reports, Vol 18, Iss 9, Pp 2175-2188 (2017)
Summary: Induction of broadly neutralizing antibodies (bnAbs) that target HIV-1 envelope (Env) is a goal of HIV-1 vaccine development. A bnAb target is the Env third variable loop (V3)-glycan site. To determine whether immunization could induce antib
Externí odkaz:
https://doaj.org/article/f020d40e9877461f93e8d9d15c7fa9e4
Autor:
Bradford M Elmer, Kurt A Swanson, Dinesh S Bangari, Peter A Piepenhagen, Errin Roberts, Tatyana Taksir, Lei Guo, Maria-Carmen Obinu, Pascal Barneoud, Susan Ryan, Bailin Zhang, Laurent Pradier, Zhi-Yong Yang, Gary J Nabel
Publikováno v:
PLoS ONE, Vol 14, Iss 12, p e0226245 (2019)
Antibody therapies for Alzheimer's Disease (AD) hold promise but have been limited by the inability of these proteins to migrate efficiently across the blood brain barrier (BBB). Central nervous system (CNS) gene transfer by vectors like adeno-associ
Externí odkaz:
https://doaj.org/article/d3951a84b17a4191bede4dca1cb53655
Autor:
Edward Seung, Zhen Xing, Lan Wu, Ercole Rao, Virna Cortez-Retamozo, Beatriz Ospina, Liqing Chen, Christian Beil, Zhili Song, Bailin Zhang, Mikhail Levit, Gejing Deng, Andrew Hebert, Patrick Kirby, Aiqun Li, Emma-Jane Poulton, Rita Vicente, Audrey Garrigou, Peter Piepenhagen, Greg Ulinski, Michele Sanicola-Nadel, Dinesh S. Bangari, Huawei Qiu, Lily Pao, Dmitri Wiederschain, Ronnie Wei, Zhi-yong Yang, Gary J. Nabel
Publikováno v:
Nature. 603:328-334
Effective antitumour immunity depends on the orchestration of potent T cell responses against malignancies
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f3a13b2ddbf0dac11fa1c3a85d09c032
https://doi.org/10.1038/s41586-022-04439-0
https://doi.org/10.1038/s41586-022-04439-0
Autor:
Ruth Hunegnaw, Anna N. Honko, Lingshu Wang, Derick Carr, Tamar Murray, Wei Shi, Lam Nguyen, Nadia Storm, Caitlyn N. M. Dulan, Kathryn E. Foulds, Krystle N. Agans, Robert W. Cross, Joan B. Geisbert, Cheng Cheng, Aurélie Ploquin, Daphne A. Stanley, Thomas W. Geisbert, Gary J. Nabel, Nancy J. Sullivan
Publikováno v:
Science Translational Medicine. 14
Marburg virus (MARV) causes a severe hemorrhagic fever disease in primates with mortality rates in humans of up to 90%. MARV has been identified as a category A bioterrorism agent by the Centers for Disease Control and Prevention (CDC) and priority p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7b701e707f1a278a6977f19ea61a6dc2
https://doi.org/10.1126/scitranslmed.abq6364
https://doi.org/10.1126/scitranslmed.abq6364
Autor:
Devi SenGupta, Pottage John C, Moses Supercharger Nsubuga, Thumbi Ndung'u, Timothy Attoye, Mitchell Warren, David Ripin, Rowena Johnston, Karine Dubé, Brian P. Doehle, Izukanji Sikazwe, Mark Dybul, Joseph M. McCune, Sharon R Lewin, Rosanne Lamplough, Steven G. Deeks, Cathy Bansbach, James F. Rooney, Adam Jiang, Gary J Nabel
Publikováno v:
Lancet HIV
The Lancet. HIV
The Lancet. HIV
Summary Developing a cure for HIV is a global priority. Target product profiles are a tool commonly used throughout the drug development process to align interested parties around a clear set of goals or requirements for a potential product. Three di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::33c2cdfcacf051134bea836828eff520
https://doi.org/10.1016/s2352-3018(20)30234-4
https://doi.org/10.1016/s2352-3018(20)30234-4
Autor:
Chih-Jen Wei, Wei Bu, Laura A. Nguyen, Joseph D. Batchelor, JungHyun Kim, Stefania Pittaluga, James R. Fuller, Hanh Nguyen, Te-Hui Chou, Jeffrey I. Cohen, Gary J. Nabel
Publikováno v:
Science Translational Medicine. 14
Epstein-Barr virus (EBV) is the major cause of infectious mononucleosis and is associated with several human cancers and, more recently, multiple sclerosis. Despite its prevalence and health impact, there are currently no vaccines or treatments. Four
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b19f247013b9259892ddf5287eddc17c
https://doi.org/10.1126/scitranslmed.abf3685
https://doi.org/10.1126/scitranslmed.abf3685