Zobrazeno 1 - 10
of 14
pro vyhledávání: '"J. N. Staniforth"'
Autor:
S. A. MacGregor, L. B. Newnes, J. N. Staniforth, G. R. Kay, M. J. Tobyn, M. D. Horrill, R. C. Lamming, D. W. Hajee
Publikováno v:
Acta Polytechnica, Vol 40, Iss 4 (2000)
The use of solid oral dosage such as tablets accounts for approximately 60 % of the total frequency of all pharmaceutical dosage forms. In addition to this 90 % of all drugs supplied are in tablet form even if they are presented in other medicinal fo
Externí odkaz:
https://doaj.org/article/a415e991edaf42d59d749e435b1d98f8
Autor:
C. K. Lim, J Silvester, Andreas J. Gescher, U Pastorino, C Bowskill, Richard D. Verschoyle, P. Carthew, Stuart M Raleigh, J N Staniforth, F Steele, David Dinsdale
Publikováno v:
British Journal of Cancer
Scopus-Elsevier
Scopus-Elsevier
Repeated oral administration of chemopreventive retinoids such as isotretinoin over extended periods of time is associated with intolerable systemic toxicity. Here isotretinoin was formulated as a powder aerosol, and its delivery to the lungs of rats
Publikováno v:
Journal of pharmaceutical sciences. 90(2)
Nedocromil sodium trihydrate is not amenable to conventional methods of dry powder inhaler formulation, including the preparation of coarse carrier systems and aggregation of the pure drug powder. It is considered that the in vitro aerosol performanc
Publikováno v:
Pharmaceutical research. 16(10)
Publikováno v:
Pharmaceutical research. 15(4)
To evaluate the use of carrier-based dry powder aerosols for inhalation delivery of proteins and examine the effect of fine particle excipients as potential formulation performance modifiers.Bovine serum albumin (BSA) was co-processed with maltodextr
Publikováno v:
Pharmaceutical research. 14(6)
To evaluate the dependence of fine particle dose charge (FPD charge) generated from powder inhalers on physico-chemical properties of the inhalation powder, inhaler type, deaggregation mechanism, dose number and/or retained powder.Electrostatic charg
Autor:
M P, Grosvenor, J N, Staniforth
Publikováno v:
Pharmaceutical research. 13(11)
The electrostatic properties of five materials commonly used in tabletting were investigated to assess their suitability for the novel technique of powder coating of pharmaceutical compacts.Powder resistivity and compact voltage decay properties were
Autor:
A, D'Emanuele, J N, Staniforth
Publikováno v:
Pharmaceutical research. 9(3)
A number of factors affecting the stability of propranolol HCl during electrophoretic control were investigated. It was found that significant degradation of propranolol HCl and hydrolysis of water occurred when a current of 15 mA was used with plati
Autor:
A, D'Emanuele, J N, Staniforth
Publikováno v:
Pharmaceutical research. 9(2)
The effects of various physicochemical parameters on the changes in drug delivery rate produced by an electrophoretic current are examined using a model system. It was shown that ionic strength has an inverse relationship with the change in delivery
Autor:
A, D'Emanuele, J N, Staniforth
Publikováno v:
Pharmaceutical research. 8(7)
A controlled drug delivery device based on the principle of electrophoresis is described. A model system using propranolol HCl and PHEMA films was used to demonstrate how control over the release of a model drug may be achieved using low constant ele