Zobrazeno 1 - 10 of 25 pro vyhledávání: '"J. N. Narendra Sharath Chandra"'
1
Design, Synthesis, Anti-Cancer Activity, and in silico Studies of Novel Imidazo[1,2-a]pyridine Derivatives
Autor: Srinivas Endoori, Srinu Bodige, J. N. Narendra Sharath Chandra, Kali Charan Gulipalli, Nareshvarma Seelam
Publikováno v: Russian Journal of General Chemistry. 90:1727-1736
A novel series of imidazo [1,2-a]pyridine derivatives has been designed, synthesized and tested for the anti-proliferative activity against three different human cancer cell lines. Most of the synthesized compounds exhibit anti-proliferative activity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c825db58c3c737f739671efacdb73448
https://doi.org/10.1134/s1070363220090212
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2
Design, Synthesis, Antitubercular and Antibacterial Activities of 1,3,5-Triazinyl Carboxamide Derivatives and In Silico Docking Studies
Autor: Srinivas Endoori, K. Ch. Gulipalli, J. N. Narendra Sharath Chandra, Nareshvarma Seelam, Srinu Bodige, P. Koteswara Rao Cherukumalli, Parameshwar Ravula
Publikováno v: Russian Journal of General Chemistry. 90:1322-1330
A series of novel N-{2-fluoro-6-[(4,6-dimethoxy-1,3,5-triazin-2-yl)methyl]phenyl} carboxamide derivatives has been synthesized, and their molecular structures are confirmed by 1H and 13C NMR, and mass spectra. Screening of the products for their anti
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19dcfc5fef2b362189b9364d30164b80
https://doi.org/10.1134/s1070363220070208
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3
Synthesis and Anticancer Activity of Novel Urea and Thiourea Bearing Thiophene-2-carboxalate Derivatives
Autor: Parameshwar Ravula, P. Koteswara Rao Cherukumalli, Srinivas Endoori, Srinu Bodige, Nareshvarma Seelam, K. Ch. Gulipalli, J. N. Narendra Sharath Chandra
Publikováno v: Russian Journal of General Chemistry. 90:1336-1344
A new series of urea and thiourea bearing thiophene-2-carboxalate derivatives has been designed against protein tyrosine phosphatase 1B (PTP1B) active site, synthesized and charecterized by 1H and 13C NMR, and mass spectra. The compounds have been ev
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::fc3e3ee2edd8ba9d9787ccc54ae96c21
https://doi.org/10.1134/s1070363220070221
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4
Synthesis and Anticancer Activity of Thiophene-2-carboxamide Derivatives and In Silico Docking Studies
Autor: Srinivas Endoori, Srinu Bodige, Parameshwar Ravula, Kali Charan Gulipalli, Nareshvarma Seelam, Purna Koteswara Rao Cherukumalli, J. N. Narendra Sharath Chandra
Publikováno v: Russian Journal of General Chemistry. 89:1502-1512
A novel series of thiophene-2-carboxamide derivatives are designed and synthesized, and their structures are confirmed by 1H and 13C NMR, and mass spectra. The synthesized compounds are evaluated for their in vitro cytotoxic activity by MTT assay. Am
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::21cca3e120b77d7351faa97f8709ecac
https://doi.org/10.1134/s1070363219070211
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5
Synthesis, Antitubercular Activity, and Molecular Docking Studies of Novel 2-(4-Chlorobenzylamino)-4-(cyclohexylmethylamino)-pyrimidine-5-carboxamides
Autor: E. Srinivas, J. N. Narendra Sharath Chandra, B. Srinu, S. Naresh Varma, Ch. P. Koteswara Rao, G. Kali Charan, R. Parameshwar
Publikováno v: Russian Journal of General Chemistry. 89:836-843
A novel series of 2-(4-chlorobenzylamino)-4-(cyclohexylmethylamino)-pyrimidine-5-carboxamide derivatives are synthesized and their structures are confirmed by 1H and 13C NMR, and MS spectral data. The compounds are screened for their antitubercular a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::31f30386a5e34c80d6515b9ff908145b
https://doi.org/10.1134/s1070363219040327
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6
Design, Synthesis and Biological Evaluation of Novel Urea and Thiourea Bearing thieno[3,2-d]-pyrimidines as PI3 Kinase Inhibitors
Autor: Nareshvarma Seelam, Srinu Bodige, Parameshwar Ravula, J. N. Narendra Sharath Chandra, Kali Charan Gulipalli, Srinivas Endoori, Purna Koteswara Rao Cherukumalli, G.R. Vanaja
Publikováno v: Anti-Cancer Agents in Medicinal Chemistry. 18:891-902
Background: Phosphatidylinositol-3-kinase α (PI3Kα) is a ubiquitous intracellular enzyme, mainly involved in intracellular signaling pathways, promotes cellular growth, proliferation, and differentiation. Therefore, inhibition of PI3K can be a hots
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::76a50b660a6dce80d15db1d85b1d3610
https://doi.org/10.2174/1871520618666180209151018
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8
Design, synthesis, in silico and in vitro evaluation of thiophene derivatives: A potent tyrosine phosphatase 1B inhibitor and anticancer activity
Autor: G.R. Vanaja, Srinivas Endoori, Srinu Bodige, Kali Charan Gulipalli, Nareshvarma Seelam, J. N. Narendra Sharath Chandra, G. Suresh Babu, Parameshwar Ravula
Publikováno v: Bioorganic & Medicinal Chemistry Letters. 27:3558-3564
A series of novel methyl 4-(4-amidoaryl)-3-methoxythiophene-2-carboxylate derivatives were designed against the active site of protein tyrosine phosphatise 1B (PTP1B) enzyme using MOE.2008.10. These molecules are also subjected for in silico toxicity
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8fb3e6a1da3e3c49dca81a0a017523e2
https://doi.org/10.1016/j.bmcl.2017.05.047
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9
Synthesis of coumarin analogs appended with quinoline and thiazole moiety and their apoptogenic role against murine ascitic carcinoma
Autor: Prabhu Thirusangu, B.R. Vijay Avin, V. Lakshmi Ranganatha, J. N. Narendra Sharath Chandra, B.T. Prabhakar, Shaukath Ara Khanum, T. Prashanth
Publikováno v: Biomedicine & Pharmacotherapy, Vol 112, Iss, Pp-(2019)
The synthesis and antiproliferative effect of a series of quinoline and thiazole containing coumarin analogs 12a-d and 13a-f respectively, on mice leukemic cells was performed. The chemical structures of newly synthesized compounds were confirmed by
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3886eeea4ee898620fa8d02fc9d2346f
http://www.sciencedirect.com/science/article/pii/S0753332218381940
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10
A novel medium size lactam ring analoges as antibacterial agents: Synthesis, biological evaluation and molecular docking studies
Autor: Putcha A. N. V., Harita, Putcha, Seshi Kumar, Guduru, Shiva Krishna Reddy, Ravula, Parameshwar, J N, Narendra Sharath Chandra
Publikováno v: EXCLI Journal
A novel series of medium size (S)-3-alkyl-3,4,6,7-tetrahydro-1H-benzo[e][1,4]diazonine-2,5-dione (6a-f) analogues were synthesized from (E)-3-(2-nitrophenyl)acrylicacid (2) reacting with various amino acid esters using Di-isopropyl Carbodiimide as a
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::857700f3e7b04c663ad53f440262598b
https://pubmed.ncbi.nlm.nih.gov/29285005
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