Zobrazeno 1 - 10
of 66
pro vyhledávání: '"J. N. McDougal"'
Publikováno v:
Fundamental and Applied Toxicology. 22:51-57
Determination of Skin:Air Partition Coefficients for Volatile Chemicals: Experimental Method and Applications. Mattie, D. R., Bates, Jr., G. D., Jepson, G. W., Fisher, J. W., and McDougal, J. N. (1994). Fundam. Appl. Toxicol. 22, 51-57. The partition
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::39134bd0a36f0a3744b760b756c739c6
https://doi.org/10.1006/faat.1994.1007
https://doi.org/10.1006/faat.1994.1007
Organic solvents like xylene are recognized as skin irritants after dermal exposure. The molecular responses to organic solvents that result in acute irritation are not understood. In the present study, we compared and quantified the molecular respon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::a57cbfa83728ff5f0844614d761d2e6e
https://doi.org/10.21236/ada453214
https://doi.org/10.21236/ada453214
Autor:
J. N. McDougal, W. W. Brinkley, C. M. Garrett, M. B. Kabbur, P. G. Gunasekar, K. T. Geiss, J. V. Rogers
Organic chemicals such as jet fuels and solvents are recognized to cause skin irritation after dermal exposure. The molecular responses to these chemicals that result in acute irritation are not understood well enough to allow the establishment and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a4610cee86ad577d0c5a4e926cf947e
https://doi.org/10.21236/ada453179
https://doi.org/10.21236/ada453179
Publikováno v:
Microscopy research and technique. 37(3)
Skin samples from Fischer-344 rats and Hartley guinea pigs exposed dermally to 1,2-dichlorobenzene (DCB) and chloropentafluorobenzene (CPFB) for up to 4 h were examined for chemical-induced damage. Samples were stained with hematoxylin and eosin and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::75dd72536d1e94a511f925d722a051d3
https://pubmed.ncbi.nlm.nih.gov/9144633
https://pubmed.ncbi.nlm.nih.gov/9144633
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 30(1)
The goal of this study was to develop a human physiologically based pharmacokinetic (PBPK) model for the chemical HCFC-123 (2,2-dichloro-1,1,1-trifluoroethane) and its major metabolite, trifluoroacetic acid (TFA). No human kinetic data for HCFC-123 a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f875c5ded3e1b134714e663a48582f72
https://pubmed.ncbi.nlm.nih.gov/8812223
https://pubmed.ncbi.nlm.nih.gov/8812223
Publikováno v:
SAR and QSAR in environmental research. 5(3)
Dermal penetration of chemicals and drugs is of concern to both toxicologists and pharmacologists. Environmental professionals try to limit exposure to chemicals using protective clothing and gloves or barrier creams to trap chemicals. Drug developer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3370adc719cdb29d3a2caeaf36f3c287
https://pubmed.ncbi.nlm.nih.gov/9114511
https://pubmed.ncbi.nlm.nih.gov/9114511
Publikováno v:
Journal of pharmaceutical sciences. 83(5)
The kinetics of water vapor absorption-desorption was studied in the porcine stratum corneum (sc) at 25 degrees C. Dry sc samples were exposed to several relative humidities followed by exposure to dry air, and the change in weight was monitored over
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::0b09fd869908ff398afbe865b55f6126
https://pubmed.ncbi.nlm.nih.gov/8071823
https://pubmed.ncbi.nlm.nih.gov/8071823
Publikováno v:
Fundamental and applied toxicology : official journal of the Society of Toxicology. 14(2)
Quantitation of chemical vapor penetration through skin is necessary for assessment of health hazards involved in some occupational environments. Information on penetration of vapors through human skin is minimal because human exposures are not sanct
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::d48745b434f54fbfe3b40ff62ba9f15a
https://pubmed.ncbi.nlm.nih.gov/2318354
https://pubmed.ncbi.nlm.nih.gov/2318354
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 247:G542-G546
Aging in humans is associated with changes in gastrointestinal function. We wanted to determine whether a similar phenomenon occurs in rats and whether rats would be a suitable model to study changes in the gastrointestinal tract with age. Intestinal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2f57e69d417c580fee3a01c03c311070
https://doi.org/10.1152/ajpgi.1984.247.5.g542
https://doi.org/10.1152/ajpgi.1984.247.5.g542
Publikováno v:
Proceedings of the Western Pharmacology Society. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::a957d5f3640638869b5953af8abf0898
https://pubmed.ncbi.nlm.nih.gov/7255478
https://pubmed.ncbi.nlm.nih.gov/7255478